Large scale production of recombinant human lactoferrin in the milk of transgenic cows

Nature Biotechnology

Volumn 20, Issue 5, 2002, Pages 484-487

  Van Berkel, Patrick H C ^a   Welling, Mick M ^b   Geerts, Marlieke ^a   Van Veen, Harry A ^a   Ravensbergen, Bep ^c   Salaheddine, Mourad ^a   Pauwels, Ernest K J ^b   Pieper, Frank ^a,b   Nuijens, Jan H ^a   Nibbering, Peter H ^c  

^a Pharming Group NV   (Netherlands)

^b Division of Nuclear Medicine   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREACTORS; DAIRY PRODUCTS; DRUG PRODUCTS; PROTEINS;

TRANSGENIC CATTLES;

BIOTECHNOLOGY;

LACTOFERRIN; RECOMBINANT HUMAN LACTOFERRIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; COW; DRUG HALF LIFE; DRUG STRUCTURE; FEMALE; IMMUNOCOMPETENCE; INDUSTRIAL PRODUCTION; IRON KINETICS; LEUKOPENIA; MALE; MILK; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN SYNTHESIS; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BIOPHARMACEUTICS; BIOTECHNOLOGY; CATTLE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; IRON; LACTOFERRIN; MALE; MICE; MILK; MONOSACCHARIDES; RECOMBINANT PROTEINS; TIME FACTORS;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0036250985     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0502-484     Document Type: Article

References (16)

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