Human lysozyme expressed in the mammary gland of transgenic dairy goats can inhibit the growth of bacteria that cause mastitis and the cold-spoilage of milk

Foodborne Pathogens and Disease

Volumn 3, Issue 4, 2006, Pages 384-392

  Maga, Elizabeth A ^a   Cullor, James S ^a   Smith, Wayne ^a   Anderson, Gary B ^a   Murray, James D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOZYME;

ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIOSTASIS; BREAST MILK; CHEESEMAKING; CONTROLLED STUDY; DAIRY INDUSTRY; ESCHERICHIA COLI; GENETIC ENGINEERING; GOAT; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LACTOCOCCUS LACTIS; MAMMARY GLAND; MASTITIS; MILK; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS FRAGI; STAPHYLOCOCCUS AUREUS; TRANSGENIC GOAT; UDDER;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTI-BACTERIAL AGENTS; BACTERIA; CONSUMER PRODUCT SAFETY; ESCHERICHIA COLI; FEMALE; GOATS; HUMANS; LACTOCOCCUS LACTIS; MASTITIS; MILK; MURAMIDASE; PSEUDOMONAS; STAPHYLOCOCCUS AUREUS;

ANIMALIA; BACTERIA (MICROORGANISMS); CAPRA HIRCUS; ESCHERICHIA COLI; LACTOCOCCUS LACTIS; PSEUDOMONAS FRAGI; STAPHYLOCOCCUS AUREUS;

EID: 33846244198     PISSN: 15353141     EISSN: None     Source Type: Journal    
DOI: 10.1089/fpd.2006.3.384     Document Type: Article

References (30)

1. Arima H, Ibrahim HR, Kinoshita T, Kato A. Bactericidal action of lysozymes attached with various sizes of hydrophobic peptides to the C-terminus using genetic modification. FEBS Lett 1997;449:93-100.
2. Bester BH, Lombard SH. Influence of lysozyme on selected bacteria associated with Gouda cheese. J Food Protect 1990;53:306-311.
3. Cagri A, Ustunol Z, Ryser ET. Antimicrobial edible films and coatings. J Food Prot 2004;67:833-848.
4. Carlsson A, Bjorck L, Persson K. Lactoferrin and lysozyme in milk during acute mastitis and their effect in Delvotest P. J Dairy Sci 1989;72:3166-3175.
5. Chandan RC, Parry RM, Shahani KM. Lysozyme, lipase, and ribonuclease in milk of various species. J Dairy Sci 1968;51:606-607.
6. Chen PW, Chen WC, Mao FC. Increase of lactoferrin concentration in mastitic goat milk. J Vet Med Sci 2003;66:345-350.
7. Costerton JW, Ingram JM, Chang KJ. Structure and function of the cell envelope of G bacteria. Bacteriol Rev 1974;38:87-110.
8. Ibrahim HR, Kobayashi K, Kato A. Length of hydrocarbon chain and antimicrobial action to Gram-negative bacteria of fatty acylated lysozyme. J Agric Food Chem 1993;41:1164-1168.
9. Ibrahim HR, Yamada M, Matsushita K, Kobayashi K, Kato A. Enhanced bactericidal activity of lysozyme to Escherichia coli by inserting a hydrophobic pentapeptide into its C-terminus. J Biol Chem 1994;269:5059-5063.
10. Irwin DM. Evolution of cow nonstomach lysozyme genes. Genome 2004;47:1082-1090.
11. Jolles P, Jolles J. What's new in lysozyme research. Mol Cell Biochem 1984;63:165-189.
12. Kerr DE, Plant K, Bramley AJ, Williamson CM, Lax AJ, Moore K, Wells KD, Wall RJ. Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice. Nat Biotechnol 2001;19:66-70.
13. Maga EA, Anderson GB, Huang MC, Murray JD. Expression of human lysozyme mRNA in the mammary gland of transgenic mice. Trans Res 1994;3:36-42.
14. Maga EA, Anderson GB, Huang MC, Murray JD. The effect of mammary gland expression of human lysozyme on the properties of milk in transgenic mice. J Dairy Sci 1995;78:2645-2652.
15. Maga EA, Anderson GB, Cullor JS, Smith W, Murray JD. The antimicrobial properties of human lysozyme transgenic mouse milk. J Food Prot 1998;61:52-56.
16. Maga EA, Sargent RG, Zeng H, Pati S, Zarling DA, Oppenheim SM, Collette NMB, Moyer AL, Conrad-Brink JS, Rowe JD, BonDurant RH, Anderson GB, Murray JD. Increased efficiency of transgenic livestock production. Trans Res 2003;12:485-196.
17. Maga EA, Shoemaker CF, Rowe JD, BonDurant RH, Anderson GB, Murray JD. Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland. J Dairy Sci 2006a;89:518-524.
18. Maga EA, Walker RK, Anderson GB, Murray JD. Consumption of milk from transgenic goats expressing human lysozyme in the mammary gland results in the modulation of intestinal microflora. Trans Res 2006b;15:515-519.
19. Masschalck B, Michiels CW. Antimicrobial properties of lysozyme in relation to foodborne vegetative bacteria. Crit Rev Microbiol 2003;29:191-214.
20. Neviani E, Gatti M, Tarelli MT, Divizia R. Lysozyme resistance of lactic acid bacteria. Latte 1996;3:90-91.
21. Osserman EF, Klockars M, Halper J, Fischel RE. Effects of lysozyme on normal and transformed cells. Nature 1973;243:331.
22. Phillips DC. The 3-dimensional structure of an enzyme molecule. Sci Am 1966;215:78-90.
23. Prieur DJ. Tissue specific deficiency of lysozyme in ruminants. Comp Biochem Physiol 1986;85:349-353.
24. Proctor VA, Cunningham FE. The chemistry of lysozyme and it use as a food preservative and pharmaceutical. Crit Rev Food Sci Nutr 1988;26:359-395.
25. Salton MRJ. The bacterial cell envelope: a historical perspective. In J. M. Ghuysen JM and Hakenbeck R (eds.): Bacterial Cell Wall. Amsterdam:Elsevier Science, 1994:1.
26. Schukken YH, Wilson DJ, Welcome F, Garrison-Tikofsky L, Gonzalez RN. Monitoring udder health and milk quality using somatic cell counts. Vet Res 2003;34:579-596.
27. Shahani KM, Chandan RC, Kelly PL, MacQuiddy EL. 1962. Determination of lysozyme in milk and factors affecting its concentration and properties. Proc 16th Intern Dairy Congr 1962;8:285-293.
28. Wall RJ, Powell AM, Paape MJ, Kerr DE, Bannerman DD, Pursel VG, Wells KD, Talbot N, Hawk HW. Genetically enhanced cows resist intramammary Staphylococcus aureus infection. Nat Biotech 2005;23:445-451.
29. White FH, McKenzie HA, Shaw DC, Pearce RJ. Studies on a partially purified bovine milk lysozyme. Biochem Int 1998;16:521-528.
30. Wilkins KM, Board RG. 1989. Natural antimicrobial systems. In Gould GW (ed.): Mechanisms of Action of Food Preservation Procedures. London: Elsevier, 1989:285-362.