28-Day repeated dose oral toxicity of recombinant human holo-lactoferrin in rats

Regulatory Toxicology and Pharmacology

Volumn 52, Issue 2, 2008, Pages 174-179

  Cerven, D ^a   DeGeorge, G ^a   Bethell, D ^b  

^a MB Research Laboratories   (United States)

^b Clinical Development   (United States)

Author keywords

Holo lactoferrin; Oral toxicity rat; Recombinant human lactoferrin; Short term toxicity

Indexed keywords

HOLO LACTOFERRIN; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; LACTOFERRIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BODY GROWTH; CLINICAL CHEMISTRY; CONTROLLED STUDY; FEMALE; FOOD INTAKE; HEMATOLOGY; HISTOPATHOLOGY; IRON BINDING CAPACITY; MALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; TOXICITY;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IRON; LACTOFERRIN; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; ORYZA SATIVA; RATS; RATS, WISTAR; SEX FACTORS; TOXICITY TESTS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 55949117486     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2008.07.003     Document Type: Article

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