c-Src/Jak2/PDGFR/PKCδ-dependent MMP-9 induction is required for thrombin-stimulated rat brain astrocytes migration

Molecular Neurobiology

Volumn 49, Issue 2, 2014, Pages 658-672

  Lin, Chih Chung ^a   Lee, I Ta ^a,b   Chi, Pei Ling ^b   Hsieh, Hsi Lung ^c   Cheng, Shin Ei ^b   Hsiao, Li Der ^b   Liu, Chiung Ju ^b   Yang, Chuen Mao ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Astrocytes; Matrix metalloproteinase 9; Neurodegeneration; Signaling pathway; Thrombin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; ACTIVATING TRANSCRIPTION FACTOR 2; CYTOMEGALOVIRUS ANTIGEN PP65; GELATINASE B; GENISTEIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; JANUS KINASE 2; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN TYROSINE KINASE; ROTTLERIN; SMALL INTERFERING RNA; THROMBIN; JAK2 PROTEIN, RAT; MMP9 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE TRANSLOCATION; GENETIC TRANSFECTION; NONHUMAN; ONCOGENE SRC; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG EFFECTS; ENZYME INDUCTION; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; BRAIN; CELL MOVEMENT; CELLS, CULTURED; ENZYME INDUCTION; GENES, SRC; JANUS KINASE 2; MATRIX METALLOPROTEINASE 9; PROTEIN KINASE C-DELTA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; THROMBIN;

EID: 84896542221     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8547-y     Document Type: Article

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