|
|
Volumn 77, Issue , 2014, Pages 185-192
|
|
Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: Identification of a lead for anti-inflammatory drug
a
a
a
a
a
a
|
|
Author keywords
Chromone; Cyclooxygenase 2; Indole; Inhibitors; Interactions; Pyrazole
|
|
Indexed keywords
1 (2,6 DICHLOROPHENYL) 3 (4 OXO 4H CHROMEN 3 YLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE;
1 (2,6 DICHLOROPHENYL) 3 (6 ISOPROPYL 4 OXO 4H CHROMEN 3 YLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE;
2 (3 CHLOROPHENYL) 4 (6 FLUORO 8 NITRO 4 OXO 4H CHROMEN 3 YLMETHYLENE) 5 METHYL 2,4 DIHYDROPYRAZOL 3 ONE;
3 (4 OXO 4H CHROMEN 3 YLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE;
3 (6 BROMO 4 OXO 4H CHROMEN 3 YLMETHYLENE) 1 (2,6 DICHLOROPHENYL) 1,3 DIHYDROINDOL 2 ONE;
3 (6 BROMO 4 OXO 4H CHROMEN 3 YLMETHYLENE) 1,3 DIHYDROINDOL 2 ONE;
ACETYLSALICYLIC ACID;
ANTIINFLAMMATORY AGENT;
ARACHIDONATE 5 LIPOXYGENASE;
ARACHIDONIC ACID;
CAPSAICIN;
CELECOXIB;
CHROMONE DERIVATIVE;
CYCLOOXYGENASE 1;
CYCLOOXYGENASE 2;
DICLOFENAC;
INDOLE DERIVATIVE;
INDOMETACIN;
PYRAZOLE DERIVATIVE;
UNCLASSIFIED DRUG;
WOGONIN;
INDOLE;
NONSTEROID ANTIINFLAMMATORY AGENT;
PROSTAGLANDIN SYNTHASE INHIBITOR;
PYRAZOLE;
ANALGESIC ACTIVITY;
ANIMAL EXPERIMENT;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
CONJUGATE;
CONTROLLED STUDY;
DRUG BIOAVAILABILITY;
DRUG DESIGN;
DRUG SCREENING;
DRUG SYNTHESIS;
ENZYME INHIBITION;
FEMALE;
IC 50;
MALE;
MASS SPECTROMETRY;
MOLECULAR DOCKING;
MOLECULAR MODEL;
MOUSE;
NONHUMAN;
NUCLEAR MAGNETIC RESONANCE;
PHYSICAL CHEMISTRY;
ANIMAL;
CHEMICAL STRUCTURE;
CHEMICALLY INDUCED;
CHEMISTRY;
DOSE RESPONSE;
METABOLISM;
PAIN;
PAIN MEASUREMENT;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ANIMALS;
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL;
CAPSAICIN;
CHROMONES;
CYCLOOXYGENASE 1;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE INHIBITORS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DESIGN;
INDOLES;
MICE;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
PAIN;
PAIN MEASUREMENT;
PYRAZOLES;
STRUCTURE-ACTIVITY RELATIONSHIP;
|
|
EID: 84896506393
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2014.03.003 Document Type: Article |
|
Times cited : (78)
|
|
References (37)
|
