Effect of wogonin, a plant flavone from scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells

Biochemical Pharmacology

Volumn 61, Issue 10, 2001, Pages 1195-1203

  Sook Chi, Yeon ^a   Sun Cheon, Bong ^a   Pyo Kim, Hyun ^a  

^a Kangwon National University   (South Korea)

Author keywords

Cyclooxygenase 2; Flavonoid; Inducible nitric oxide synthase; Nitric oxide; Prostaglandin; RAW 264.7; Wogonin

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 2; FLAVONE DERIVATIVE; LIPOPOLYSACCHARIDE; MIFEPRISTONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHOLIPASE A2; PREDNISOLONE; PROSTAGLANDIN E2; SCUTELLARIAE RADIX; STEROID RECEPTOR; WOGONIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; INHIBITION KINETICS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DRUG INTERACTIONS; ENZYME INDUCTION; FLAVANONES; FLAVONOIDS; GENE SILENCING; ISOENZYMES; LIPOPOLYSACCHARIDES; MICE; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0035873932     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00597-4     Document Type: Article

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