메뉴 건너뛰기




Volumn 50, Issue 1, 2014, Pages 82-92

Potentiation of Tbx5-mediated transactivation by SUMO conjugation and protein inhibitor of activated STAT 1 (PIAS1)

Author keywords

PIAS; SUMO; SUMO E3 ligase; TBX5

Indexed keywords

PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN INHIBITOR OF ACTIVATED STAT 1; SUMO PROTEIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TBX5; UNCLASSIFIED DRUG; STAT1 PROTEIN; SUMO 1 PROTEIN; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR 5;

EID: 84896505444     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.02.007     Document Type: Article
Times cited : (19)

References (51)
  • 2
    • 84859941402 scopus 로고    scopus 로고
    • PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation
    • N.S. Belaguli, M. Zhang, A.H. Garcia, and D.H. Berger PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation PLoS One 7 2012 e35717
    • (2012) PLoS One , vol.7 , pp. 35717
    • Belaguli, N.S.1    Zhang, M.2    Garcia, A.H.3    Berger, D.H.4
  • 5
    • 84856505104 scopus 로고    scopus 로고
    • Conditional ablation of ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival
    • L. Chen, Y. Ma, E.Y. Kim, W. Yu, R.J. Schwartz, and L. Qian et al. Conditional ablation of ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival PLoS One 7 2012 e31005
    • (2012) PLoS One , vol.7 , pp. 31005
    • Chen, L.1    Ma, Y.2    Kim, E.Y.3    Yu, W.4    Schwartz, R.J.5    Qian, L.6
  • 6
    • 84882770264 scopus 로고    scopus 로고
    • Sumoylation regulates nuclear localization and function of zinc finger transcription factor ZIC3
    • L. Chen, Y. Ma, L. Qian, and J. Wang Sumoylation regulates nuclear localization and function of zinc finger transcription factor ZIC3 Biochim Biophys Acta 1833 2013 2725 2733
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 2725-2733
    • Chen, L.1    Ma, Y.2    Qian, L.3    Wang, J.4
  • 7
    • 0030725378 scopus 로고    scopus 로고
    • Specific inhibition of Stat3 signal transduction by PIAS3
    • DOI 10.1126/science.278.5344.1803
    • C.D. Chung, J. Liao, B. Liu, X. Rao, P. Jay, and P. Berta et al. Specific inhibition of Stat3 signal transduction by PIAS3 Science 278 1997 1803 1805 (Pubitemid 27527648)
    • (1997) Science , vol.278 , Issue.5344 , pp. 1803-1805
    • Chung, C.D.1    Liao, J.2    Liu, B.3    Rao, X.4    Jay, P.5    Berta, P.6    Shuai, K.7
  • 8
    • 83755181571 scopus 로고    scopus 로고
    • SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function
    • L. Cong, S.B. Pakala, K. Ohshiro, D.Q. Li, and R. Kumar SUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor function J Biol Chem 286 2011 43793 43808
    • (2011) J Biol Chem , vol.286 , pp. 43793-43808
    • Cong, L.1    Pakala, S.B.2    Ohshiro, K.3    Li, D.Q.4    Kumar, R.5
  • 10
    • 0037424497 scopus 로고    scopus 로고
    • Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome
    • DOI 10.1074/jbc.M208120200
    • C. Fan, M. Liu, and Q. Wang Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome J Biol Chem 278 2003 8780 8785 (Pubitemid 36800635)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 8780-8785
    • Fan, C.1    Liu, M.2    Wang, Q.3
  • 11
    • 70350543964 scopus 로고    scopus 로고
    • SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle
    • C. Figueroa-Romero, J.A. Iniguez-Lluhi, J. Stadler, C.R. Chang, D. Arnoult, and P.J. Keller et al. SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle FASEB J 23 2009 3917 3927
    • (2009) FASEB J , vol.23 , pp. 3917-3927
    • Figueroa-Romero, C.1    Iniguez-Lluhi, J.A.2    Stadler, J.3    Chang, C.R.4    Arnoult, D.5    Keller, P.J.6
  • 13
    • 44949133142 scopus 로고    scopus 로고
    • Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation
    • R. Georges, G. Nemer, M. Morin, C. Lefebvre, and M. Nemer Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation Mol Cell Biol 28 2008 4052 4067
    • (2008) Mol Cell Biol , vol.28 , pp. 4052-4067
    • Georges, R.1    Nemer, G.2    Morin, M.3    Lefebvre, C.4    Nemer, M.5
  • 14
    • 0035445835 scopus 로고    scopus 로고
    • Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
    • T.K. Ghosh, E.A. Packham, A.J. Bonser, T.E. Robinson, S.J. Cross, and J.D. Brook Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome Hum Mol Genet 10 2001 1983 1994 (Pubitemid 32910543)
    • (2001) Human Molecular Genetics , vol.10 , Issue.18 , pp. 1983-1994
    • Ghosh, T.K.1    Packham, E.A.2    Bonser, A.J.3    Robinson, T.E.4    Cross, S.J.5    Brook, J.D.6
  • 15
    • 64649085563 scopus 로고    scopus 로고
    • Physical interaction between TBX5 and MEF2C is required for early heart development
    • T.K. Ghosh, F.F. Song, E.A. Packham, S. Buxton, T.E. Robinson, and J. Ronksley et al. Physical interaction between TBX5 and MEF2C is required for early heart development Mol Cell Biol 29 2009 2205 2218
    • (2009) Mol Cell Biol , vol.29 , pp. 2205-2218
    • Ghosh, T.K.1    Song, F.F.2    Packham, E.A.3    Buxton, S.4    Robinson, T.E.5    Ronksley, J.6
  • 18
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • DOI 10.1038/90123
    • Y. Hiroi, S. Kudoh, K. Monzen, Y. Ikeda, Y. Yazaki, and R. Nagai et al. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation Nat Genet 28 2001 276 280 (Pubitemid 32626032)
    • (2001) Nature Genetics , vol.28 , Issue.3 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6    Komuro, I.7
  • 21
    • 77956518725 scopus 로고    scopus 로고
    • PIAS1 regulates CP2c localization and active promoter complex formation in erythroid cell-specific alpha-globin expression
    • H.C. Kang, J.H. Chae, J. Jeon, W. Kim, D.H. Ha, and J.H. Shin et al. PIAS1 regulates CP2c localization and active promoter complex formation in erythroid cell-specific alpha-globin expression Nucleic Acids Res 38 2010 5456 5471
    • (2010) Nucleic Acids Res , vol.38 , pp. 5456-5471
    • Kang, H.C.1    Chae, J.H.2    Jeon, J.3    Kim, W.4    Ha, D.H.5    Shin, J.H.6
  • 22
    • 79958198042 scopus 로고    scopus 로고
    • Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects
    • E.Y. Kim, L. Chen, Y. Ma, W. Yu, J. Chang, and I.P. Moskowitz et al. Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects PLoS One 6 2011 e20803
    • (2011) PLoS One , vol.6 , pp. 20803
    • Kim, E.Y.1    Chen, L.2    Ma, Y.3    Yu, W.4    Chang, J.5    Moskowitz, I.P.6
  • 23
    • 84857626547 scopus 로고    scopus 로고
    • Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction
    • E.Y. Kim, L. Chen, Y. Ma, W. Yu, J. Chang, and I.P. Moskowitz et al. Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction J Mol Cell Cardiol 52 2012 638 649
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 638-649
    • Kim, E.Y.1    Chen, L.2    Ma, Y.3    Yu, W.4    Chang, J.5    Moskowitz, I.P.6
  • 25
    • 0033977682 scopus 로고    scopus 로고
    • Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies
    • DOI 10.1128/MCB.20.3.1072-1082.2000
    • F. Lehembre, P. Badenhorst, S. Muller, A. Travers, F. Schweisguth, and A. Dejean Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies Mol Cell Biol 20 2000 1072 1082 (Pubitemid 30044244)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.3 , pp. 1072-1082
    • Lehembre, F.1    Badenhorst, P.2    Muller, S.3    Travers, A.4    Schweisguth, F.5    Dejean, A.6
  • 26
    • 80053900364 scopus 로고    scopus 로고
    • The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death
    • B.B. Leitao, M.C. Jones, and J.J. Brosens The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death FASEB J 25 2011 3416 3425
    • (2011) FASEB J , vol.25 , pp. 3416-3425
    • Leitao, B.B.1    Jones, M.C.2    Brosens, J.J.3
  • 27
    • 2542489214 scopus 로고    scopus 로고
    • Regulation of Smad4 sumoylation and transforming growth factor-β signaling by protein inhibitor of activated STAT1
    • DOI 10.1074/jbc.M401554200
    • M. Liang, F. Melchior, X.H. Feng, and X. Lin Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1 J Biol Chem 279 2004 22857 22865 (Pubitemid 38685586)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.22 , pp. 22857-22865
    • Liang, M.1    Melchior, F.2    Feng, X.-H.3    Lin, X.4
  • 28
    • 0034234753 scopus 로고    scopus 로고
    • Ventricular expression of tbx5 inhibits normal heart chamber development
    • DOI 10.1006/dbio.2000.9748
    • C.M. Liberatore, R.D. Searcy-Schrick, and K.E. Yutzey Ventricular expression of tbx5 inhibits normal heart chamber development Dev Biol 223 2000 169 180 (Pubitemid 30439527)
    • (2000) Developmental Biology , vol.223 , Issue.1 , pp. 169-180
    • Liberatore, C.M.1    Searcy-Schrick, R.D.2    Yutzey, K.E.3
  • 30
    • 4644367257 scopus 로고    scopus 로고
    • PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity
    • DOI 10.1038/ni1104
    • B. Liu, S. Mink, K.A. Wong, N. Stein, C. Getman, and P.W. Dempsey et al. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity Nat Immunol 5 2004 891 898 (Pubitemid 39276233)
    • (2004) Nature Immunology , vol.5 , Issue.9 , pp. 891-898
    • Liu, B.1    Mink, S.2    Wong, K.A.3    Stein, N.4    Getman, C.5    Dempsey, P.W.6    Wu, H.7    Shuai, K.8
  • 31
  • 33
    • 84869091913 scopus 로고    scopus 로고
    • Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair
    • I. Psakhye, and S. Jentsch Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair Cell 151 2012 807 820
    • (2012) Cell , vol.151 , pp. 807-820
    • Psakhye, I.1    Jentsch, S.2
  • 34
    • 0035918226 scopus 로고    scopus 로고
    • SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting
    • M.S. Rodriguez, C. Dargemont, and R.T. Hay SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting J Biol Chem 276 2001 12654 12659
    • (2001) J Biol Chem , vol.276 , pp. 12654-12659
    • Rodriguez, M.S.1    Dargemont, C.2    Hay, R.T.3
  • 35
    • 33745227290 scopus 로고    scopus 로고
    • The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. Elegans
    • DOI 10.1016/j.ydbio.2006.04.001, PII S0012160606002521
    • S. Roy Chowdhuri, T. Crum, A. Woollard, S. Aslam, and P.G. Okkema The T-box factor TBX-2 and the SUMO conjugating enzyme UBC-9 are required for ABa-derived pharyngeal muscle in C. elegans Dev Biol 295 2006 664 677 (Pubitemid 43927702)
    • (2006) Developmental Biology , vol.295 , Issue.2 , pp. 664-677
    • Roy Chowdhuri, S.1    Crum, T.2    Woollard, A.3    Aslam, S.4    Okkema, P.G.5
  • 37
    • 33645514646 scopus 로고    scopus 로고
    • PIAS proteins and transcriptional regulation - More than just SUMO E3 ligases?
    • A.D. Sharrocks PIAS proteins and transcriptional regulation - more than just SUMO E3 ligases? Genes Dev 20 2006 754 758
    • (2006) Genes Dev , vol.20 , pp. 754-758
    • Sharrocks, A.D.1
  • 38
    • 32644459132 scopus 로고    scopus 로고
    • Regulation of cytokine signaling pathways by PIAS proteins
    • DOI 10.1038/sj.cr.7310027, PII 7310027
    • K. Shuai Regulation of cytokine signaling pathways by PIAS proteins Cell Res 16 2006 196 202 (Pubitemid 43247977)
    • (2006) Cell Research , vol.16 , Issue.2 , pp. 196-202
    • Shuai, K.1
  • 39
    • 34147208064 scopus 로고    scopus 로고
    • An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved ψKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity
    • DOI 10.1128/MCB.01098-06
    • N. Stankovic-Valentin, S. Deltour, J. Seeler, S. Pinte, G. Vergoten, and C. Guerardel et al. An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity Mol Cell Biol 27 2007 2661 2675 (Pubitemid 46581356)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.7 , pp. 2661-2675
    • Stankovic-Valentin, N.1    Deltour, S.2    Seeler, J.3    Pinte, S.4    Vergoten, G.5    Guerardel, C.6    Dejean, A.7    Leprince, D.8
  • 40
    • 77953689090 scopus 로고    scopus 로고
    • Structural basis of TBX5-DNA recognition: The T-box domain in its DNA-bound and -unbound form
    • C.U. Stirnimann, D. Ptchelkine, C. Grimm, and C.W. Muller Structural basis of TBX5-DNA recognition: the T-box domain in its DNA-bound and -unbound form J Mol Biol 400 2010 71 81
    • (2010) J Mol Biol , vol.400 , pp. 71-81
    • Stirnimann, C.U.1    Ptchelkine, D.2    Grimm, C.3    Muller, C.W.4
  • 41
    • 33846019234 scopus 로고    scopus 로고
    • Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics
    • DOI 10.1074/mcp.M600212-MCP200
    • A.C. Vertegaal, J.S. Andersen, S.C. Ogg, R.T. Hay, M. Mann, and A.I. Lamond Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics Mol Cell Proteomics 5 2006 2298 2310 (Pubitemid 46040634)
    • (2006) Molecular and Cellular Proteomics , vol.5 , Issue.12 , pp. 2298-2310
    • Vertegaal, A.C.O.1    Andersen, J.S.2    Ogg, S.C.3    Hay, R.T.4    Mann, M.5    Lamond, A.I.6
  • 42
    • 80052282066 scopus 로고    scopus 로고
    • Synergistic activation of cardiac genes by myocardin and Tbx5
    • C. Wang, D. Cao, Q. Wang, and D.Z. Wang Synergistic activation of cardiac genes by myocardin and Tbx5 PLoS One 6 2011 e24242
    • (2011) PLoS One , vol.6 , pp. 24242
    • Wang, C.1    Cao, D.2    Wang, Q.3    Wang, D.Z.4
  • 44
    • 10344252331 scopus 로고    scopus 로고
    • SUMO-1 modification activated GATA4-dependent cardiogenic gene activity
    • DOI 10.1074/jbc.M407494200
    • J. Wang, X.H. Feng, and R.J. Schwartz SUMO-1 modification activated GATA4-dependent cardiogenic gene activity J Biol Chem 279 2004 49091 49098 (Pubitemid 39625791)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49091-49098
    • Wang, J.1    Feng, X.-H.2    Schwartz, R.J.3
  • 45
    • 33846182262 scopus 로고    scopus 로고
    • Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts
    • DOI 10.1128/MCB.01160-06
    • J. Wang, A. Li, Z. Wang, X. Feng, E.N. Olson, and R.J. Schwartz Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts Mol Cell Biol 27 2007 622 632 (Pubitemid 46080129)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.2 , pp. 622-632
    • Wang, J.1    Li, A.2    Wang, Z.3    Feng, X.4    Olson, E.N.5    Schwartz, R.J.6
  • 46
    • 27644591989 scopus 로고    scopus 로고
    • Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4
    • DOI 10.1128/MCB.25.22.9829-9844.2005
    • J. Wang, P. Paradis, A. Aries, H. Komati, C. Lefebvre, and H. Wang et al. Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4 Mol Cell Biol 25 2005 9829 9844 (Pubitemid 41572733)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.22 , pp. 9829-9844
    • Wang, J.1    Paradis, P.2    Aries, A.3    Komati, H.4    Lefebvre, C.5    Wang, H.6    Nemer, M.7
  • 47
    • 77954729858 scopus 로고    scopus 로고
    • Sumoylation and regulation of cardiac gene expression
    • J. Wang, and R.J. Schwartz Sumoylation and regulation of cardiac gene expression Circ Res 107 2010 19 29
    • (2010) Circ Res , vol.107 , pp. 19-29
    • Wang, J.1    Schwartz, R.J.2
  • 48
    • 84877133485 scopus 로고    scopus 로고
    • Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity
    • J. Wang, Z. Sun, Z. Zhang, I. Saadi, X. Li, and S. Gao et al. Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity J Biol Chem 288 2013 12580 12595
    • (2013) J Biol Chem , vol.288 , pp. 12580-12595
    • Wang, J.1    Sun, Z.2    Zhang, Z.3    Saadi, I.4    Li, X.5    Gao, S.6
  • 49
    • 53149119958 scopus 로고    scopus 로고
    • Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier
    • J. Wang, H. Zhang, D. Iyer, X.H. Feng, and R.J. Schwartz Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier J Biol Chem 283 2008 23235 23243
    • (2008) J Biol Chem , vol.283 , pp. 23235-23243
    • Wang, J.1    Zhang, H.2    Iyer, D.3    Feng, X.H.4    Schwartz, R.J.5
  • 50
    • 1842839997 scopus 로고    scopus 로고
    • Identification of the TBX5 transactivating domain and the nuclear localization signal
    • DOI 10.1016/j.gene.2004.01.017, PII S0378111904000381
    • M.V. Zaragoza, L.E. Lewis, G. Sun, E. Wang, L. Li, and I. Said-Salman et al. Identification of the TBX5 transactivating domain and the nuclear localization signal Gene 330 2004 9 18 (Pubitemid 38490413)
    • (2004) Gene , vol.330 , Issue.1-2 , pp. 9-18
    • Zaragoza, M.V.1    Lewis, L.E.2    Sun, G.3    Wang, E.4    Li, L.5    Said-Salman, I.6    Feucht, L.7    Huang, T.8
  • 51
    • 84868322244 scopus 로고    scopus 로고
    • A role for protein inhibitor of activated STAT 1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors
    • Y. Zhang, Z. Gan, P. Huang, L. Zhou, T. Mao, and M. Shao et al. A role for protein inhibitor of activated STAT 1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors J Biol Chem 287 2012 37973 37985
    • (2012) J Biol Chem , vol.287 , pp. 37973-37985
    • Zhang, Y.1    Gan, Z.2    Huang, P.3    Zhou, L.4    Mao, T.5    Shao, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.