-
1
-
-
33749361499
-
Gene regulatory networks in the evolution and development of the heart
-
Olson EN, (2006) Gene regulatory networks in the evolution and development of the heart. Science 313: 1922-1927.
-
(2006)
Science
, vol.313
, pp. 1922-1927
-
-
Olson, E.N.1
-
2
-
-
33748621746
-
Making or breaking the heart: from lineage determination to morphogenesis
-
Srivastava D, (2006) Making or breaking the heart: from lineage determination to morphogenesis. Cell 126: 1037-1048.
-
(2006)
Cell
, vol.126
, pp. 1037-1048
-
-
Srivastava, D.1
-
4
-
-
2442648749
-
TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed
-
Mori AD, Bruneau BG, (2004) TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed. Curr Opin Cardiol 19: 211-215.
-
(2004)
Curr Opin Cardiol
, vol.19
, pp. 211-215
-
-
Mori, A.D.1
Bruneau, B.G.2
-
5
-
-
0030636780
-
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome
-
Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, et al. (1997) Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet 15: 30-35.
-
(1997)
Nat Genet
, vol.15
, pp. 30-35
-
-
Basson, C.T.1
Bachinsky, D.R.2
Lin, R.C.3
Levi, T.4
Elkins, J.A.5
-
6
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
Li QY, Newbury-Ecob RA, Terrett JA, Wilson DI, Curtis AR, et al. (1997) Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet 15: 21-29.
-
(1997)
Nat Genet
, vol.15
, pp. 21-29
-
-
Li, Q.Y.1
Newbury-Ecob, R.A.2
Terrett, J.A.3
Wilson, D.I.4
Curtis, A.R.5
-
7
-
-
33745076019
-
The human TBX5 gene mutation database
-
Heinritz W, Shou L, Moschik A, Froster UG, (2005) The human TBX5 gene mutation database. Hum Mutat 26: 397.
-
(2005)
Hum Mutat
, vol.26
, pp. 397
-
-
Heinritz, W.1
Shou, L.2
Moschik, A.3
Froster, U.G.4
-
8
-
-
28844438924
-
T-box transcription factors and their roles in regulatory hierarchies in the developing heart
-
Stennard FA, Harvey RP, (2005) T-box transcription factors and their roles in regulatory hierarchies in the developing heart. Development 132: 4897-4910.
-
(2005)
Development
, vol.132
, pp. 4897-4910
-
-
Stennard, F.A.1
Harvey, R.P.2
-
9
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, et al. (2001) A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 106: 709-721.
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
Charron, F.4
Robitaille, L.5
-
10
-
-
0035445835
-
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
-
Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, et al. (2001) Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet 10: 1983-1994.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1983-1994
-
-
Ghosh, T.K.1
Packham, E.A.2
Bonser, A.J.3
Robinson, T.E.4
Cross, S.J.5
-
11
-
-
0034234753
-
Ventricular expression of tbx5 inhibits normal heart chamber development
-
Liberatore CM, Searcy-Schrick RD, Yutzey KE, (2000) Ventricular expression of tbx5 inhibits normal heart chamber development. Dev Biol 223: 169-180.
-
(2000)
Dev Biol
, vol.223
, pp. 169-180
-
-
Liberatore, C.M.1
Searcy-Schrick, R.D.2
Yutzey, K.E.3
-
12
-
-
0019835945
-
Malformation syndrome of duplication 12q24.1 leads to qter
-
Melnyk AR, Weiss L, Van Dyke DL, Jarvi P, (1981) Malformation syndrome of duplication 12q24.1 leads to qter. Am J Med Genet 10: 357-365.
-
(1981)
Am J Med Genet
, vol.10
, pp. 357-365
-
-
Melnyk, A.R.1
Weiss, L.2
van Dyke, D.L.3
Jarvi, P.4
-
13
-
-
0027499058
-
Mosaicism for duplication 12q (12q13-->q24.2) in a dysmorphic male infant
-
Dixon JW, Costa T, Teshima IE, (1993) Mosaicism for duplication 12q (12q13-->q24.2) in a dysmorphic male infant. J Med Genet 30: 70-72.
-
(1993)
J Med Genet
, vol.30
, pp. 70-72
-
-
Dixon, J.W.1
Costa, T.2
Teshima, I.E.3
-
14
-
-
0034931034
-
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
-
Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, et al. (2001) Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet 28: 276-280.
-
(2001)
Nat Genet
, vol.28
, pp. 276-280
-
-
Hiroi, Y.1
Kudoh, S.2
Monzen, K.3
Ikeda, Y.4
Yazaki, Y.5
-
15
-
-
34250754981
-
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development
-
Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, et al. (2007) A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell 129: 1365-1376.
-
(2007)
Cell
, vol.129
, pp. 1365-1376
-
-
Moskowitz, I.P.1
Kim, J.B.2
Moore, M.L.3
Wolf, C.M.4
Peterson, M.A.5
-
16
-
-
0043267988
-
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
-
Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, et al. (2003) GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424: 443-447.
-
(2003)
Nature
, vol.424
, pp. 443-447
-
-
Garg, V.1
Kathiriya, I.S.2
Barnes, R.3
Schluterman, M.K.4
King, I.N.5
-
17
-
-
64649085563
-
Physical interaction between TBX5 and MEF2C is required for early heart development
-
Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, et al. (2009) Physical interaction between TBX5 and MEF2C is required for early heart development. Mol Cell Biol 29: 2205-2218.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2205-2218
-
-
Ghosh, T.K.1
Song, F.F.2
Packham, E.A.3
Buxton, S.4
Robinson, T.E.5
-
18
-
-
0141615095
-
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
-
Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, et al. (2003) Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol 262: 206-224.
-
(2003)
Dev Biol
, vol.262
, pp. 206-224
-
-
Stennard, F.A.1
Costa, M.W.2
Elliott, D.A.3
Rankin, S.4
Haast, S.J.5
-
19
-
-
58649091740
-
Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development
-
Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, et al. (2009) Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol 326: 368-377.
-
(2009)
Dev Biol
, vol.326
, pp. 368-377
-
-
Maitra, M.1
Schluterman, M.K.2
Nichols, H.A.3
Richardson, J.A.4
Lo, C.W.5
-
20
-
-
44449162472
-
Tbx5-dependent pathway regulating diastolic function in congenital heart disease
-
Zhu Y, Gramolini AO, Walsh MA, Zhou YQ, Slorach C, et al. (2008) Tbx5-dependent pathway regulating diastolic function in congenital heart disease. Proc Natl Acad Sci U S A 105: 5519-5524.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5519-5524
-
-
Zhu, Y.1
Gramolini, A.O.2
Walsh, M.A.3
Zhou, Y.Q.4
Slorach, C.5
-
21
-
-
31744444444
-
Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart
-
Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, et al. (2006) Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet 38: 175-183.
-
(2006)
Nat Genet
, vol.38
, pp. 175-183
-
-
Koshiba-Takeuchi, K.1
Takeuchi, J.K.2
Arruda, E.P.3
Kathiriya, I.S.4
Mo, R.5
-
22
-
-
0037424497
-
Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome
-
Fan C, Liu M, Wang Q, (2003) Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome. J Biol Chem 278: 8780-8785.
-
(2003)
J Biol Chem
, vol.278
, pp. 8780-8785
-
-
Fan, C.1
Liu, M.2
Wang, Q.3
-
23
-
-
0035967868
-
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor
-
Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, et al. (2001) Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105: 851-862.
-
(2001)
Cell
, vol.105
, pp. 851-862
-
-
Wang, D.1
Chang, P.S.2
Wang, Z.3
Sutherland, L.4
Richardson, J.A.5
-
24
-
-
5444235587
-
Control of smooth muscle development by the myocardin family of transcriptional coactivators
-
Wang DZ, Olson EN, (2004) Control of smooth muscle development by the myocardin family of transcriptional coactivators. Curr Opin Genet Dev 14: 558-566.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 558-566
-
-
Wang, D.Z.1
Olson, E.N.2
-
25
-
-
33745152386
-
The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis
-
Pipes GC, Creemers EE, Olson EN, (2006) The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev 20: 1545-1556.
-
(2006)
Genes Dev
, vol.20
, pp. 1545-1556
-
-
Pipes, G.C.1
Creemers, E.E.2
Olson, E.N.3
-
26
-
-
0041422285
-
The serum response factor coactivator myocardin is required for vascular smooth muscle development
-
Li S, Wang DZ, Wang Z, Richardson JA, Olson EN, (2003) The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A 100: 9366-9370.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9366-9370
-
-
Li, S.1
Wang, D.Z.2
Wang, Z.3
Richardson, J.A.4
Olson, E.N.5
-
27
-
-
0037069365
-
Potentiation of serum response factor activity by a family of myocardin-related transcription factors
-
Wang DZ, Li S, Hockemeyer D, Sutherland L, Wang Z, et al. (2002) Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A 99: 14855-14860.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14855-14860
-
-
Wang, D.Z.1
Li, S.2
Hockemeyer, D.3
Sutherland, L.4
Wang, Z.5
-
28
-
-
21144455710
-
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development
-
Li J, Zhu X, Chen M, Cheng L, Zhou D, et al. (2005) Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A 102: 8916-8921.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8916-8921
-
-
Li, J.1
Zhu, X.2
Chen, M.3
Cheng, L.4
Zhou, D.5
-
29
-
-
27244437468
-
Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation
-
Oh J, Richardson JA, Olson EN, (2005) Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proc Natl Acad Sci U S A 102: 15122-15127.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15122-15127
-
-
Oh, J.1
Richardson, J.A.2
Olson, E.N.3
-
30
-
-
33746505444
-
Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function
-
Sun Y, Boyd K, Xu W, Ma J, Jackson CW, et al. (2006) Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function. Mol Cell Biol 26: 5809-5826.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5809-5826
-
-
Sun, Y.1
Boyd, K.2
Xu, W.3
Ma, J.4
Jackson, C.W.5
-
31
-
-
33947727502
-
Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation
-
Parmacek MS, (2007) Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation. Circ Res 100: 633-644.
-
(2007)
Circ Res
, vol.100
, pp. 633-644
-
-
Parmacek, M.S.1
-
32
-
-
73249136731
-
Myocardin is required for cardiomyocyte survival and maintenance of heart function
-
Huang J, Min Lu M, Cheng L, Yuan LJ, Zhu X, et al. (2009) Myocardin is required for cardiomyocyte survival and maintenance of heart function. Proc Natl Acad Sci U S A 106: 18734-18739.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18734-18739
-
-
Huang, J.1
Min Lu, M.2
Cheng, L.3
Yuan, L.J.4
Zhu, X.5
-
33
-
-
4544224539
-
Target gene-specific modulation of myocardin activity by GATA transcription factors
-
Oh J, Wang Z, Wang DZ, Lien CL, Xing W, et al. (2004) Target gene-specific modulation of myocardin activity by GATA transcription factors. Mol Cell Biol 24: 8519-8528.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8519-8528
-
-
Oh, J.1
Wang, Z.2
Wang, D.Z.3
Lien, C.L.4
Xing, W.5
-
34
-
-
1642297200
-
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression
-
Wang Z, Wang DZ, Hockemeyer D, McAnally J, Nordheim A, et al. (2004) Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature 428: 185-189.
-
(2004)
Nature
, vol.428
, pp. 185-189
-
-
Wang, Z.1
Wang, D.Z.2
Hockemeyer, D.3
McAnally, J.4
Nordheim, A.5
-
35
-
-
11144250262
-
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin
-
Cao D, Wang Z, Zhang CL, Oh J, Xing W, et al. (2005) Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol 25: 364-376.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 364-376
-
-
Cao, D.1
Wang, Z.2
Zhang, C.L.3
Oh, J.4
Xing, W.5
-
36
-
-
27944454815
-
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes
-
Callis TE, Cao D, Wang DZ, (2005) Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circ Res 97: 992-1000.
-
(2005)
Circ Res
, vol.97
, pp. 992-1000
-
-
Callis, T.E.1
Cao, D.2
Wang, D.Z.3
-
37
-
-
42149168469
-
Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression
-
Tang RH, Zheng XL, Callis TE, Stansfield WE, He J, et al. (2008) Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proc Natl Acad Sci U S A 105: 3362-3367.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3362-3367
-
-
Tang, R.H.1
Zheng, X.L.2
Callis, T.E.3
Stansfield, W.E.4
He, J.5
-
38
-
-
22944451474
-
Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin
-
Liu ZP, Wang Z, Yanagisawa H, Olson EN, (2005) Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Dev Cell 9: 261-270.
-
(2005)
Dev Cell
, vol.9
, pp. 261-270
-
-
Liu, Z.P.1
Wang, Z.2
Yanagisawa, H.3
Olson, E.N.4
-
39
-
-
0036773632
-
Myocardin: a component of a molecular switch for smooth muscle differentiation
-
Chen J, Kitchen CM, Streb JW, Miano JM, (2002) Myocardin: a component of a molecular switch for smooth muscle differentiation. J Mol Cell Cardiol 34: 1345-1356.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 1345-1356
-
-
Chen, J.1
Kitchen, C.M.2
Streb, J.W.3
Miano, J.M.4
-
40
-
-
33748489726
-
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis
-
Mori AD, Zhu Y, Vahora I, Nieman B, Koshiba-Takeuchi K, et al. (2006) Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Dev Biol 297: 566-586.
-
(2006)
Dev Biol
, vol.297
, pp. 566-586
-
-
Mori, A.D.1
Zhu, Y.2
Vahora, I.3
Nieman, B.4
Koshiba-Takeuchi, K.5
-
41
-
-
33846232336
-
Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development
-
Bimber B, Dettman RW, Simon HG, (2007) Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development. Dev Biol 302: 230-242.
-
(2007)
Dev Biol
, vol.302
, pp. 230-242
-
-
Bimber, B.1
Dettman, R.W.2
Simon, H.G.3
-
42
-
-
33746633394
-
LMP4 regulates Tbx5 protein subcellular localization and activity
-
Camarata T, Bimber B, Kulisz A, Chew TL, Yeung J, et al. (2006) LMP4 regulates Tbx5 protein subcellular localization and activity. J Cell Biol 174: 339-348.
-
(2006)
J Cell Biol
, vol.174
, pp. 339-348
-
-
Camarata, T.1
Bimber, B.2
Kulisz, A.3
Chew, T.L.4
Yeung, J.5
-
43
-
-
0037093383
-
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation
-
Habets PE, Moorman AF, Clout DE, van Roon MA, Lingbeek M, et al. (2002) Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev 16: 1234-1246.
-
(2002)
Genes Dev
, vol.16
, pp. 1234-1246
-
-
Habets, P.E.1
Moorman, A.F.2
Clout, D.E.3
van Roon, M.A.4
Lingbeek, M.5
-
44
-
-
14044260623
-
Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis
-
Brown DD, Martz SN, Binder O, Goetz SC, Price BM, et al. (2005) Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis. Development 132: 553-563.
-
(2005)
Development
, vol.132
, pp. 553-563
-
-
Brown, D.D.1
Martz, S.N.2
Binder, O.3
Goetz, S.C.4
Price, B.M.5
-
45
-
-
21044446280
-
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation
-
Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, et al. (2005) Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development 132: 2451-2462.
-
(2005)
Development
, vol.132
, pp. 2451-2462
-
-
Stennard, F.A.1
Costa, M.W.2
Lai, D.3
Biben, C.4
Furtado, M.B.5
|