Structural basis of TBX5-DNA recognition: The T-box domain in Its DNA-bound and -unbound form

Journal of Molecular Biology

Volumn 400, Issue 1, 2010, Pages 71-81

  Stirnimann, Christian U ^a   Ptchelkine, Denis ^a,b,c   Grimm, Clemens ^b,d   Müller, Christoph W ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^c CEA SACLAY   (France)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Crystal structure; DNA binding affinities; Holt Oram syndrome; Protein DNA interaction; TBX5

Indexed keywords

DNA; MUTANT PROTEIN; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX5;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA PROTEIN COMPLEX; DNA SEQUENCE; GENE DELETION; GENE EXPRESSION REGULATION; HEART DEVELOPMENT; HOLT ORAM SYNDROME; ISOTHERMAL TITRATION CALORIMETRY; LIMB DEVELOPMENT; LIMB MALFORMATION; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; THERMOSTABILITY;

EID: 77953689090     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.04.052     Document Type: Article

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