-
2
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
DOI 10.1038/nature04444, PII NATURE04444
-
Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R (2006) Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439(7077):682-687 (Pubitemid 43237609)
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
3
-
-
0027211058
-
Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules
-
Baskar S, Ostrand Rosenberg S, Nabavi N, Nadler LM, Freeman GJ, Glimcher LH (1993) Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules. Proc Natl Acad Sci USA 90(12):5687-5690 (Pubitemid 23176226)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.12
, pp. 5687-5690
-
-
Baskar, S.1
Ostrand-Rosenberg, S.2
Nabavi, N.3
Nadler, L.M.4
Freeman, G.J.5
Glimcher, L.H.6
-
4
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, Chen S, Salay TM, Alaparthy S, Grosso JF, Korman AJ, Parker SM, Agrawal S, Goldberg SM, Pardoll DM, Gupta A, Wigginton JM (2012) Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 366(26):2455-2465
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
Pitot, H.C.11
Hamid, O.12
Bhatia, S.13
Martins, R.14
Eaton, K.15
Chen, S.16
Salay, T.M.17
Alaparthy, S.18
Grosso, J.F.19
Korman, A.J.20
Parker, S.M.21
Agrawal, S.22
Goldberg, S.M.23
Pardoll, D.M.24
Gupta, A.25
Wigginton, J.M.26
more..
-
5
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
DOI 10.1038/nm863
-
Curiel TJ, Wei S, Dong H, Alvarez X, Cheng P, Mottram P, Krzysiek R, Knutson KL, Daniel B, Zimmermann MC, David O, Burow M, Gordon A, Dhurandhar N, Myers L, Berggren R, Hemminki A, Alvarez RD, Emilie D, Curiel DT, Chen L, Zou W (2003) Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med 9(5):562-567 (Pubitemid 36597102)
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Krzysiek, R.7
Knutson, K.L.8
Daniel, B.9
Zimmermann, M.C.10
David, O.11
Burow, M.12
Gordon, A.13
Dhurandhar, N.14
Myers, L.15
Berggren, R.16
Hemminki, A.17
Alvarez, R.D.18
Emilie, D.19
Curiel, D.T.20
Chen, L.21
Zou, W.22
more..
-
6
-
-
30144444279
-
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
-
DOI 10.1172/JCI25947
-
Dannull J, Su Z, Rizzieri D, Yang BK, Coleman D, Yancey D, Zhang A, Dahm P, Chao N, Gilboa E, Vieweg J (2005) Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 115(12):3623-3633 (Pubitemid 43121851)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3623-3633
-
-
Dannull, J.1
Su, Z.2
Rizzieri, D.3
Yang, B.K.4
Coleman, D.5
Yancey, D.6
Zhang, A.7
Dahm, P.8
Chao, N.9
Gilboa, E.10
Vieweg, J.11
-
7
-
-
84864645131
-
Programmed elimination of cells by caspase-independent cell extrusion in C. elegans
-
Denning DP, Hatch V, Horvitz HR (2012) Programmed elimination of cells by caspase-independent cell extrusion in C. elegans. Nature 488(7410):226-230
-
(2012)
Nature
, vol.488
, Issue.7410
, pp. 226-230
-
-
Denning, D.P.1
Hatch, V.2
Horvitz, H.R.3
-
8
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, Lennon VA, Celis E, Chen L (2002) Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 8(8): 793-800
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
Lennon, V.A.11
Celis, E.12
Chen, L.13
-
9
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K, Chen L (1999) B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 5(12):1365-1369
-
(1999)
Nat Med
, vol.5
, Issue.12
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
10
-
-
49249089425
-
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
-
Fife BT, Bluestone JA (2008) Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev 224(8):166-182
-
(2008)
Immunol Rev
, vol.224
, Issue.8
, pp. 166-182
-
-
Fife, B.T.1
Bluestone, J.A.2
-
11
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 192(7):1027-1034
-
(2000)
J Exp Med
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
12
-
-
79953306651
-
Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma
-
Frigola X, Inman BA, Lohse CM, Krco CJ, Cheville JC, Thompson RH, Leibovich B, Blute ML, Dong H, Kwon ED (2011) Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clin Cancer Res 17(7):1915-1923
-
(2011)
Clin Cancer Res
, vol.17
, Issue.7
, pp. 1915-1923
-
-
Frigola, X.1
Inman, B.A.2
Lohse, C.M.3
Krco, C.J.4
Cheville, J.C.5
Thompson, R.H.6
Leibovich, B.7
Blute, M.L.8
Dong, H.9
Kwon, E.D.10
-
13
-
-
37849028844
-
Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
-
Furset G, Floisand Y, Sioud M (2008) Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands. Immunology 123(2):263-271
-
(2008)
Immunology
, vol.123
, Issue.2
, pp. 263-271
-
-
Furset, G.1
Floisand, Y.2
Sioud, M.3
-
14
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646-674
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
15
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
DOI 10.1126/science.1079490
-
Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299(5609):1057-1061 (Pubitemid 36222930)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
16
-
-
84856731500
-
Immune suppression in the tumor microenvironment: A role for dendritic cell-mediated tolerization of T cells
-
Hurwitz AA, Watkins SK (2012) Immune suppression in the tumor microenvironment: a role for dendritic cell-mediated tolerization of T cells. Cancer Immunol Immunother 61(2):289-293
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.2
, pp. 289-293
-
-
Hurwitz, A.A.1
Watkins, S.K.2
-
17
-
-
0032843875
-
Tumor-induced immune dysfunction
-
DOI 10.1007/s002620050586
-
Kiessling R, Wasserman K, Horiguchi S, Kono K, Sjoberg J, Pisa P, Petersson M (1999) Tumor-induced immune dysfunction. Cancer Immunol Immunother 48(7):353-362 (Pubitemid 29461387)
-
(1999)
Cancer Immunology Immunotherapy
, vol.48
, Issue.7
, pp. 353-362
-
-
Kiessling, R.1
Wasserman, K.2
Horiguchi, S.3
Kono, K.4
Sjoberg, J.5
Pisa, P.6
Petersson, M.7
-
18
-
-
78049276260
-
+ regulatory T cells improves effective therapeutic vaccination against established melanoma
-
+ regulatory T cells improves effective therapeutic vaccination against established melanoma. Cancer Res 70(20):7788-7799
-
(2010)
Cancer Res
, vol.70
, Issue.20
, pp. 7788-7799
-
-
Klages, K.1
Mayer, C.T.2
Lahl, K.3
Loddenkemper, C.4
Teng, M.W.5
Ngiow, S.F.6
Smyth, M.J.7
Hamann, A.8
Huehn, J.9
Sparwasser, T.10
-
19
-
-
84890430223
-
Functional characterization of Foxp3-specific spontaneous immune responses
-
Jul 1 doi: 10.1038/leu.2013.196
-
Larsen SK, Munir S, Woetmann A, Froesig TM, Odum N, Svane IM, Becker JC, Andersen MH (2013) Functional characterization of Foxp3-specific spontaneous immune responses. Leukemia Jul 1. doi: 10.1038/leu.2013.196
-
(2013)
Leukemia
-
-
Larsen, S.K.1
Munir, S.2
Woetmann, A.3
Froesig, T.M.4
Odum, N.5
Svane, I.M.6
Becker, J.C.7
Andersen, M.H.8
-
20
-
-
84863924314
-
Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: A current perspective
-
Le DT, Jaffee EM (2012) Regulatory T-cell modulation using cyclophosphamide in vaccine approaches: a current perspective. Cancer Res 72(14):3439-3444
-
(2012)
Cancer Res
, vol.72
, Issue.14
, pp. 3439-3444
-
-
Le, D.T.1
Jaffee, E.M.2
-
21
-
-
77958039494
-
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion
-
Muller AJ, DuHadaway JB, Chang MY, Ramalingam A, Sutanto-Ward E, Boulden J, Soler AP, Mandik-Nayak L, Gilmour SK, Prendergast GC (2010) Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion. Cancer Immunol Immunother 59(11):1655-1663
-
(2010)
Cancer Immunol Immunother
, vol.59
, Issue.11
, pp. 1655-1663
-
-
Muller, A.J.1
DuHadaway, J.B.2
Chang, M.Y.3
Ramalingam, A.4
Sutanto-Ward, E.5
Boulden, J.6
Soler, A.P.7
Mandik-Nayak, L.8
Gilmour, S.K.9
Prendergast, G.C.10
-
22
-
-
84875442610
-
HLA-restricted cytotoxic T cells that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients
-
Munir S, Andersen GH, Met O, Donia M, Frosig TM, Larsen SK, Klausen TW, Svane IM, Andersen MH (2013) HLA-restricted cytotoxic T cells that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients. Cancer Res 73(6):1674-1776
-
(2013)
Cancer Res
, vol.73
, Issue.6
, pp. 1674-1776
-
-
Munir, S.1
Andersen, G.H.2
Met, O.3
Donia, M.4
Frosig, T.M.5
Larsen, S.K.6
Klausen, T.W.7
Svane, I.M.8
Andersen, M.H.9
-
24
-
-
84887316694
-
Cutaneous T cell lymphoma cells are targets for immune checkpoint ligand PD-L1-specific, cytotoxic T cells
-
doi:10.1038/leu.2013.118
-
Munir S, Andersen GH, Woetmann A, Odum N, Becker JC, Andersen MH (2013) Cutaneous T cell lymphoma cells are targets for immune checkpoint ligand PD-L1-specific, cytotoxic T cells. Leukemia 27(11):2251-2253. doi:10.1038/leu.2013.118
-
(2013)
Leukemia
, vol.27
, Issue.11
, pp. 2251-2253
-
-
Munir, S.1
Andersen, G.H.2
Woetmann, A.3
Odum, N.4
Becker, J.C.5
Andersen, M.H.6
-
25
-
-
84859990707
-
+ T-cell responses against indoleamine 2,3-dioxygenase
-
doi:10.1371/journal.pone.0034568
-
+ T-cell responses against indoleamine 2,3-dioxygenase. PLoS One 7(4):e34568. doi:10.1371/journal.pone. 0034568
-
(2012)
PLoS One
, vol.7
, Issue.4
-
-
Munir, S.1
Larsen, S.K.2
Iversen, T.Z.3
Donia, M.4
Klausen, T.W.5
Svane, I.M.6
Thor Straten, P.7
Andersen, M.H.8
-
26
-
-
34248173331
-
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
-
DOI 10.1172/JCI31178
-
Munn DH, Mellor AL (2007) Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 117(5):1147-1154 (Pubitemid 46718399)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1147-1154
-
-
Munn, D.H.1
Mellor, A.L.2
-
27
-
-
33846519492
-
Vaccination against the forkhead family transcription factor Foxp3 enhances tumor immunity
-
DOI 10.1158/0008-5472.CAN-06-2903
-
Nair S, Boczkowski D, Fassnacht M, Pisetsky D, Gilboa E (2007) Vaccination against the forkhead family transcription factor Foxp3 enhances tumor immunity. Cancer Res 67(1):371-380 (Pubitemid 46150755)
-
(2007)
Cancer Research
, vol.67
, Issue.1
, pp. 371-380
-
-
Nair, S.1
Boczkowski, D.2
Fassnacht, M.3
Pisetsky, D.4
Gilboa, E.5
-
28
-
-
0034045874
-
Receptor selection in B and T lymphocytes
-
Nemazee D (2000) Receptor selection in B and T lymphocytes. Annu Rev Immunol 18:19-51
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 19-51
-
-
Nemazee, D.1
-
29
-
-
0035525739
-
+ cells: A naturally occurring population of regulatory T cells
-
+ cells: a naturally occurring population of regulatory T cells. Blood 98(9):2736-2744
-
(2001)
Blood
, vol.98
, Issue.9
, pp. 2736-2744
-
-
Ng, W.F.1
Duggan, P.J.2
Ponchel, F.3
Matarese, G.4
Lombardi, G.5
Edwards, A.D.6
Isaacs, J.D.7
Lechler, R.I.8
-
30
-
-
79954465132
-
Molecular mechanisms of T-cell tolerance
-
Nurieva RI, Liu X, Dong C (2011) Molecular mechanisms of T-cell tolerance. Immunol Rev 241(1):133-144
-
(2011)
Immunol Rev
, vol.241
, Issue.1
, pp. 133-144
-
-
Nurieva, R.I.1
Liu, X.2
Dong, C.3
-
31
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, Schumacher T, Jestaedt L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Daimling A, Wick W, Platten M (2011) An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478(7368):197-203
-
(2011)
Nature
, vol.478
, Issue.7368
, pp. 197-203
-
-
Opitz, C.A.1
Litzenburger, U.M.2
Sahm, F.3
Ott, M.4
Tritschler, I.5
Trump, S.6
Schumacher, T.7
Jestaedt, L.8
Schrenk, D.9
Weller, M.10
Jugold, M.11
Guillemin, G.J.12
Miller, C.L.13
Lutz, C.14
Radlwimmer, B.15
Lehmann, I.16
Von Daimling, A.17
Wick, W.18
Platten, M.19
-
32
-
-
84865760928
-
Regulating the suppressors: Apoptosis and inflammation govern the survival of tumor-induced myeloid-derived suppressor cells (MDSC)
-
Ostrand-Rosenberg S, Sinha P, Chornoguz O, Ecker C (2012) Regulating the suppressors: apoptosis and inflammation govern the survival of tumor-induced myeloid-derived suppressor cells (MDSC). Cancer Immunol Immunother 61(8):1319-1325
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.8
, pp. 1319-1325
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
Chornoguz, O.3
Ecker, C.4
-
33
-
-
33846295218
-
FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis
-
DOI 10.1016/j.cell.2006.12.029, PII S0092867407000475
-
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA (2007) FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 128(2):309-323 (Pubitemid 46123514)
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 309-323
-
-
Paik, J.-H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
Miao, L.7
Tothova, Z.8
Horner, J.W.9
Carrasco, D.R.10
Jiang, S.11
Gilliland, D.G.12
Chin, L.13
Wong, W.H.14
Castrillon, D.H.15
DePinho, R.A.16
-
34
-
-
80052020183
-
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
-
Pallotta MT, Orabona C, Volpi C, Vacca C, Belladonna ML, Bianchi R, Servillo G, Brunacci C, Calvitti M, Bicciato S, Mazza EM, Boon L, Grassi F, Fioretti MC, Fallarino F, Puccetti P, Grohmann U (2011) Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol 12(9):870-878
-
(2011)
Nat Immunol
, vol.12
, Issue.9
, pp. 870-878
-
-
Pallotta, M.T.1
Orabona, C.2
Volpi, C.3
Vacca, C.4
Belladonna, M.L.5
Bianchi, R.6
Servillo, G.7
Brunacci, C.8
Calvitti, M.9
Bicciato, S.10
Mazza, E.M.11
Boon, L.12
Grassi, F.13
Fioretti, M.C.14
Fallarino, F.15
Puccetti, P.16
Grohmann, U.17
-
35
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12(4):252-264
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
-
36
-
-
38649107388
-
IDO-expressing regulatory dendritic cells in cancer and chronic infection
-
DOI 10.1007/s00109-007-0262-6
-
Popov A, Schultze JL (2008) IDO-expressing regulatory dendritic cells in cancer and chronic infection. J Mol Med 86(2):145-160 (Pubitemid 351172124)
-
(2008)
Journal of Molecular Medicine
, vol.86
, Issue.2
, pp. 145-160
-
-
Popov, A.1
Schultze, J.L.2
-
37
-
-
43549095276
-
HO-1 underlies resistance of AML cells to TNF-induced apoptosis
-
Rushworth SA, MacEwan DJ (2008) HO-1 underlies resistance of AML cells to TNF-induced apoptosis. Blood 111(7):3793-3801
-
(2008)
Blood
, vol.111
, Issue.7
, pp. 3793-3801
-
-
Rushworth, S.A.1
MacEwan, D.J.2
-
40
-
-
38349011021
-
Indoleamine 2,3-dioxygenase (IDO): The antagonist of type I interferon-driven skin inflammation?
-
Scheler M, Wenzel J, Tuting T, Takikawa O, Bieber T, von Bubnoff D (2007) Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? Am J Pathol 171(6):1936-1943
-
(2007)
Am J Pathol
, vol.171
, Issue.6
, pp. 1936-1943
-
-
Scheler, M.1
Wenzel, J.2
Tuting, T.3
Takikawa, O.4
Bieber, T.5
Von Bubnoff, D.6
-
41
-
-
84878589185
-
Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma
-
Sevko A, Sade-Feldman M, Kanterman J, Michels T, Falk CS, Umansky L, Ramacher M, Kato M, Schadendorf D, Baniyash M, Umansky V (2013) Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma. J Invest Dermatol 133(6):1610-1619
-
(2013)
J Invest Dermatol
, vol.133
, Issue.6
, pp. 1610-1619
-
-
Sevko, A.1
Sade-Feldman, M.2
Kanterman, J.3
Michels, T.4
Falk, C.S.5
Umansky, L.6
Ramacher, M.7
Kato, M.8
Schadendorf, D.9
Baniyash, M.10
Umansky, V.11
-
42
-
-
84866242667
-
IDO is a nodal pathogenic driver of lung cancer and metastasis development
-
Smith C, Chang MY, Parker KH, Beury DW, DuHadaway JB, Flick HE, Boulden J, Sutanto-Ward E, Soler AP, Laury-Kleintop LD, Mandik-Nayak L, Metz R, Ostrand-Rosenberg S, Prendergast GC, Muller AJ (2012) IDO is a nodal pathogenic driver of lung cancer and metastasis development. Cancer Discov 2(8):722-735
-
(2012)
Cancer Discov
, vol.2
, Issue.8
, pp. 722-735
-
-
Smith, C.1
Chang, M.Y.2
Parker, K.H.3
Beury, D.W.4
DuHadaway, J.B.5
Flick, H.E.6
Boulden, J.7
Sutanto-Ward, E.8
Soler, A.P.9
Laury-Kleintop, L.D.10
Mandik-Nayak, L.11
Metz, R.12
Ostrand-Rosenberg, S.13
Prendergast, G.C.14
Muller, A.J.15
-
43
-
-
70249098095
-
The immune system strikes back: Cellular immune responses against indoleamine 2,3-dioxygenase
-
doi:10.1371/journal.pone.0006910
-
Sorensen RB, Berge-Hansen L, Junker N, Hansen CA, Hadrup SR, Schumacher TN, Svane IM, Becker JC, Thor SP, Andersen MH (2009) The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase. PLoS One 4(9):e6910. doi:10.1371/journal.pone.0006910
-
(2009)
PLoS One
, vol.4
, Issue.9
-
-
Sorensen, R.B.1
Berge-Hansen, L.2
Junker, N.3
Hansen, C.A.4
Hadrup, S.R.5
Schumacher, T.N.6
Svane, I.M.7
Becker, J.C.8
Thor, S.P.9
Andersen, M.H.10
-
44
-
-
79951820132
-
Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators
-
Sorensen RB, Hadrup SR, Svane IM, Hjortso MC, thor Straten P, Andersen MH (2011) Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators. Blood 117(7):2200-2210
-
(2011)
Blood
, vol.117
, Issue.7
, pp. 2200-2210
-
-
Sorensen, R.B.1
Hadrup, S.R.2
Svane, I.M.3
Hjortso, M.C.4
Thor Straten, P.5
Andersen, M.H.6
-
45
-
-
79952762101
-
Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2
-
Sorensen RB, Kollgaard T, Andersen RS, van den Berg JH, Svane IM, thor Straten P, Andersen MH (2011) Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2. Cancer Res 71(6):2038-2044
-
(2011)
Cancer Res
, vol.71
, Issue.6
, pp. 2038-2044
-
-
Sorensen, R.B.1
Kollgaard, T.2
Andersen, R.S.3
Van Den Berg, J.H.4
Svane, I.M.5
Thor Straten, P.6
Andersen, M.H.7
-
47
-
-
24344489044
-
+ T cells dominate the memory compartments of exposed subjects
-
+ T cells dominate the memory compartments of exposed subjects. J Exp Med 202(5):673-685
-
(2005)
J Exp Med
, vol.202
, Issue.5
, pp. 673-685
-
-
Sylwester, A.W.1
Mitchell, B.L.2
Edgar, J.B.3
Taormina, C.4
Pelte, C.5
Ruchti, F.6
Sleath, P.R.7
Grabstein, K.H.8
Hosken, N.A.9
Kern, F.10
Nelson, J.A.11
Picker, L.J.12
-
48
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M (2012) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 366(26):2443-2453
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2453
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
Horn, L.14
Drake, C.G.15
Pardoll, D.M.16
Chen, L.17
Sharfman, W.H.18
Anders, R.A.19
Taube, J.M.20
McMiller, T.L.21
Xu, H.22
Korman, A.J.23
Jure-Kunkel, M.24
Agrawal, S.25
McDonald, D.26
Kollia, G.D.27
Gupta, A.28
Wigginton, J.M.29
Sznol, M.30
more..
-
49
-
-
79953323468
-
FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer
-
Watkins SK, Zhu Z, Riboldi E, Shafer-Weaver KA, Stagliano KE, Sklavos MM, Ambs S, Yagita H, Hurwitz AA (2011) FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer. J Clin Invest 121(4):1361-1372
-
(2011)
J Clin Invest
, vol.121
, Issue.4
, pp. 1361-1372
-
-
Watkins, S.K.1
Zhu, Z.2
Riboldi, E.3
Shafer-Weaver, K.A.4
Stagliano, K.E.5
Sklavos, M.M.6
Ambs, S.7
Yagita, H.8
Hurwitz, A.A.9
-
50
-
-
34247561382
-
Dendritic cell based antitumor vaccination: Impact of functional indoleamine 2,3-dioxygenase expression
-
DOI 10.1007/s00262-006-0256-1
-
Wobser M, Voigt H, Houben R, Eggert AO, Freiwald M, Kaemmerer U, Kaempgen E, Schrama D, Becker JC (2007) Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression. Cancer Immunol Immunother 56(7):1017-1024 (Pubitemid 46675300)
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.7
, pp. 1017-1024
-
-
Wobser, M.1
Voigt, H.2
Houben, R.3
Eggert, A.O.4
Freiwald, M.5
Kaemmerer, U.6
Kaempgen, E.7
Schrama, D.8
Becker, J.C.9
-
51
-
-
0037111483
-
Expression of programmed death 1 ligands by murine T cells and APC
-
Yamazaki T, Akiba H, Iwai H, Matsuda H, Aoki M, Tanno Y, Shin T, Tsuchiya H, Pardoll DM, Okumura K, Azuma M, Yagita H (2002) Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 169(10):5538-5545 (Pubitemid 35291652)
-
(2002)
Journal of Immunology
, vol.169
, Issue.10
, pp. 5538-5545
-
-
Yamazaki, T.1
Akiba, H.2
Iwai, H.3
Matsuda, H.4
Aoki, M.5
Tanno, Y.6
Shin, T.7
Tsuchiya, H.8
Pardoll, D.M.9
Okumura, K.10
Azuma, M.11
Yagita, H.12
-
52
-
-
84875462761
-
Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer
-
Yu J, Du W, Yan F, Wang Y, Li H, Cao S, Yu W, Shen C, Liu J, Ren X (2013) Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer. J Immunol 190(7):3783-3797
-
(2013)
J Immunol
, vol.190
, Issue.7
, pp. 3783-3797
-
-
Yu, J.1
Du, W.2
Yan, F.3
Wang, Y.4
Li, H.5
Cao, S.6
Yu, W.7
Shen, C.8
Liu, J.9
Ren, X.10
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