Cytotoxicity of mutant huntingtin fragment in yeast can be modulated by the expression level of wild type huntingtin fragment

ACS Chemical Neuroscience

Volumn 5, Issue 3, 2014, Pages 205-215

  Saleh, Aliabbas Ahmedbhai ^a   Bhadra, Ankan Kumar ^a   Roy, Ipsita ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Chaperone; gene dosage; huntingtin; Huntington's disease; protein misfolding

Indexed keywords

GALACTOSE; HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; HTT PROTEIN, HUMAN; NERVE PROTEIN; PEPTIDE;

ALLELE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE DOSAGE; GENE EXPRESSION; HUNTINGTON CHOREA; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; REDUCTION; SACCHAROMYCES CEREVISIAE; SOLUBILITY; WILD TYPE; YEAST CELL; CELL SURVIVAL; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOBLOTTING; METABOLISM; MUTATION; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS;

CELL SURVIVAL; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; IMMUNOBLOTTING; MUTATION; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; PEPTIDES; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SOLUBILITY; TRANSFECTION;

EID: 84896459033     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn400171d     Document Type: Article

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