메뉴 건너뛰기




Volumn 114, Issue 3, 2008, Pages 161-170

Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: Effect of starvation

Author keywords

Carnitine palmitoyltransferase I; Contact sites; Malonyl CoA; Mitochondria; Outer membranes; Starvation

Indexed keywords

CARNITINE; CARNITINE PALMITOYLTRANSFERASE; MALONYL COENZYME A;

EID: 47549108272     PISSN: 13813455     EISSN: 17444160     Source Type: Journal    
DOI: 10.1080/13813450802181062     Document Type: Article
Times cited : (9)

References (47)
  • 1
    • 0037232725 scopus 로고    scopus 로고
    • Relative importance of malonyl-CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart
    • Besikci AO, Campbell FM, Hopkins TA, Dyck JRB, Lopaschuk GD. 2003. Relative importance of malonyl-CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart. Am J Physiol 284:H283-9.
    • (2003) Am J Physiol , vol.284
    • Besikci, A.O.1    Campbell, F.M.2    Hopkins, T.A.3    Dyck, J.R.B.4    Lopaschuk, G.D.5
  • 2
    • 0022382089 scopus 로고
    • Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation
    • Brady LJ, Silverstein LJ, Hoppel CL, Brady PS. 1985. Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. Biochem J 232:445-50.
    • (1985) Biochem J , vol.232 , pp. 445-450
    • Brady, L.J.1    Silverstein, L.J.2    Hoppel, C.L.3    Brady, P.S.4
  • 3
    • 0017876814 scopus 로고
    • Carnitine metabolism in the fasting rat
    • Brass EP, Hoppel CL. 1978. Carnitine metabolism in the fasting rat. J Biol Chem 253:2688-93.
    • (1978) J Biol Chem , vol.253 , pp. 2688-2693
    • Brass, E.P.1    Hoppel, C.L.2
  • 4
    • 0019798351 scopus 로고
    • The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA
    • Bremer J. 1981. The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. Biochim Biophys Acta 665:628-31.
    • (1981) Biochim Biophys Acta , vol.665 , pp. 628-631
    • Bremer, J.1
  • 5
    • 0026549217 scopus 로고
    • Regulation of the expression of the mitochondrial 3-hydroxy-3- methylglutaryl-CoA synthase gene. Its role in the control of ketogenesis
    • Casals N, Roca N, Guerrero M, Gil-Gomez G, Ayte J, Ciudad CJ, Hegardt FG. 1992. Regulation of the expression of the mitochondrial 3-hydroxy-3- methylglutaryl-CoA synthase gene. Its role in the control of ketogenesis. Biochem J 283:261-4.
    • (1992) Biochem J , vol.283 , pp. 261-264
    • Casals, N.1    Roca, N.2    Guerrero, M.3    Gil-Gomez, G.4    Ayte, J.5    Ciudad, C.J.6    Hegardt, F.G.7
  • 6
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng YC, Prusoff WH. 1973. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22:3099-108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.C.1    Prusoff, W.H.2
  • 7
    • 0033850969 scopus 로고    scopus 로고
    • Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo
    • Chien D, Dean D, Saha AK, Flatt JP, Ruderman NB. 2000. Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. Am J Physiol 279:E259-65.
    • (2000) Am J Physiol , vol.279
    • Chien, D.1    Dean, D.2    Saha, A.K.3    Flatt, J.P.4    Ruderman, N.B.5
  • 8
    • 0017839019 scopus 로고
    • Ketogenesis and malonyl coenzyme A content of isolated rat hepatocytes
    • Cook GA, King MT, Veech RL. 1978. Ketogenesis and malonyl coenzyme A content of isolated rat hepatocytes. J Biol Chem 253:2529-31.
    • (1978) J Biol Chem , vol.253 , pp. 2529-2531
    • Cook, G.A.1    King, M.T.2    Veech, R.L.3
  • 9
    • 0021193646 scopus 로고
    • Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in Ki values
    • Cook GA. 1984. Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in Ki values. J Biol Chem 259:12030-33.
    • (1984) J Biol Chem , vol.259 , pp. 12030-12033
    • Cook, G.A.1
  • 10
    • 0034972285 scopus 로고    scopus 로고
    • Differential regulation of carnitine palmitoyltransferase-I gene isoforms (CPT-I alpha and CPT-I beta) in the rat heart
    • Cook GA, Edwards TL, Jansen MS, Bahouth SW, Wilcox HG, Park EA. 2001. Differential regulation of carnitine palmitoyltransferase-I gene isoforms (CPT-I alpha and CPT-I beta) in the rat heart. J Mol Cell Cardiol 33:317-29.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 317-329
    • Cook, G.A.1    Edwards, T.L.2    Jansen, M.S.3    Bahouth, S.W.4    Wilcox, H.G.5    Park, E.A.6
  • 11
    • 0016582509 scopus 로고
    • Hepatic mitochondrial function in ketogenic states
    • DiMarco JP, Hoppel C. 1975. Hepatic mitochondrial function in ketogenic states. J Clin Invest 55:1237-44.
    • (1975) J Clin Invest , vol.55 , pp. 1237-1244
    • DiMarco, J.P.1    Hoppel, C.2
  • 12
    • 77049143386 scopus 로고
    • The determination of enzyme inhibitor constants
    • Dixon M. 1953. The determination of enzyme inhibitor constants. Biochem J 55:170-1.
    • (1953) Biochem J , vol.55 , pp. 170-171
    • Dixon, M.1
  • 13
    • 0029793298 scopus 로고    scopus 로고
    • Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over β-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states
    • Drynan L, Quant PA, Zammit VA. 1996. Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over β-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states. Biochem J 317:791-5.
    • (1996) Biochem J , vol.317 , pp. 791-795
    • Drynan, L.1    Quant, P.A.2    Zammit, V.A.3
  • 14
    • 17144389851 scopus 로고    scopus 로고
    • Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity
    • Faye A, Borthwick K, Esnous C, Price NT, Gobin S, Jackson VN, Zammit VA, Girard J, Prip-Buus C. 2005. Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity. Biochem J 387:67-76.
    • (2005) Biochem J , vol.387 , pp. 67-76
    • Faye, A.1    Borthwick, K.2    Esnous, C.3    Price, N.T.4    Gobin, S.5    Jackson, V.N.6    Zammit, V.A.7    Girard, J.8    Prip-Buus, C.9
  • 15
    • 0032518861 scopus 로고    scopus 로고
    • Enrichment of carnitine palmitoyltransferases I and II in the contact sites of rat liver mitochondria
    • Fraser F, Zammit VA. 1998. Enrichment of carnitine palmitoyltransferases I and II in the contact sites of rat liver mitochondria. Biochem J 329:225-9.
    • (1998) Biochem J , vol.329 , pp. 225-229
    • Fraser, F.1    Zammit, V.A.2
  • 16
    • 0035827646 scopus 로고    scopus 로고
    • Distinct kinetics of carnitine palmitoyltransferase I in contact sites and outer membranes of rat liver mitochondria
    • Fraser F, Padovese R, Zammit VA. 2001. Distinct kinetics of carnitine palmitoyltransferase I in contact sites and outer membranes of rat liver mitochondria. J Biol Chem 276:20182-5.
    • (2001) J Biol Chem , vol.276 , pp. 20182-20185
    • Fraser, F.1    Padovese, R.2    Zammit, V.A.3
  • 17
    • 0028818499 scopus 로고
    • Flexibility of zonation of fatty acid oxidation in rat liver
    • Guzman M, Bijleveld C, Geelen MJH. 1995. Flexibility of zonation of fatty acid oxidation in rat liver. Biochem J 311:853-60.
    • (1995) Biochem J , vol.311 , pp. 853-860
    • Guzman, M.1    Bijleveld, C.2    Geelen, M.J.H.3
  • 18
    • 0032483331 scopus 로고    scopus 로고
    • The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria
    • Hoppel CL, Kerner J, Turkaly P, Turkaly J, Tandler B. 1998. The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria. J Biol Chem 273:23495-503.
    • (1998) J Biol Chem , vol.273 , pp. 23495-23503
    • Hoppel, C.L.1    Kerner, J.2    Turkaly, P.3    Turkaly, J.4    Tandler, B.5
  • 19
    • 0035881548 scopus 로고    scopus 로고
    • Rat liver mitochondrial contact sites and carnitine palmitoyltransferase-I
    • Hoppel C, Kerner J, Turkaly P, Tandler B. 2001. Rat liver mitochondrial contact sites and carnitine palmitoyltransferase-I. Arch Biochem Biophys 392:321-5.
    • (2001) Arch Biochem Biophys , vol.392 , pp. 321-325
    • Hoppel, C.1    Kerner, J.2    Turkaly, P.3    Tandler, B.4
  • 20
    • 0036498771 scopus 로고    scopus 로고
    • Isolation of hepatic mitochondrial contact sites: Previously unrecognized inner membrane components
    • Hoppel C, Kerner J, Turkaly P, Minkler P, Tandler B. 2002. Isolation of hepatic mitochondrial contact sites: previously unrecognized inner membrane components. Anal Biochem 302:60-9.
    • (2002) Anal Biochem , vol.302 , pp. 60-69
    • Hoppel, C.1    Kerner, J.2    Turkaly, P.3    Minkler, P.4    Tandler, B.5
  • 22
    • 0034717940 scopus 로고    scopus 로고
    • Fatty acid import into mitochondria
    • Kerner J, Hoppel C. 2000. Fatty acid import into mitochondria. Biochim Biophys Acta 1486:1-17.
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 1-17
    • Kerner, J.1    Hoppel, C.2
  • 23
    • 4444277089 scopus 로고    scopus 로고
    • Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: Effect on the kinetic properties of the enzyme
    • Kerner J, Distler AM, Parland W, Peterman SM, Hoppel CL. 2004. Phosphorylation of rat liver mitochondrial carnitine palmitoyltransferase-I: effect on the kinetic properties of the enzyme. J Biol Chem 279:41104-13.
    • (2004) J Biol Chem , vol.279 , pp. 41104-41113
    • Kerner, J.1    Distler, A.M.2    Parland, W.3    Peterman, S.M.4    Hoppel, C.L.5
  • 24
    • 0026596855 scopus 로고
    • Development and characterization of a polyclonal antibody against rat liver mitochondrial overt carnitine palmitoyltransferase (CPT I). Distinction of CPT I from CPT II and of isoforms of CPT I in different tissues
    • Kolodziej MP, Crilly PJ, Corstorphine CG, Zammit VA. 1992. Development and characterization of a polyclonal antibody against rat liver mitochondrial overt carnitine palmitoyltransferase (CPT I). Distinction of CPT I from CPT II and of isoforms of CPT I in different tissues. Biochem J 282:415-21.
    • (1992) Biochem J , vol.282 , pp. 415-421
    • Kolodziej, M.P.1    Crilly, P.J.2    Corstorphine, C.G.3    Zammit, V.A.4
  • 25
    • 0014516051 scopus 로고
    • Rates of ketone body formation in the perfused rat liver
    • Krebs HA, Wallace PG, Hems R, Freeland RA. 1969. Rates of ketone body formation in the perfused rat liver. Biochem J 112:595-600.
    • (1969) Biochem J , vol.112 , pp. 595-600
    • Krebs, H.A.1    Wallace, P.G.2    Hems, R.3    Freeland, R.A.4
  • 26
    • 0842308112 scopus 로고    scopus 로고
    • Expression of three carnitine palmitoyltransferase-I isoforms in 10 regions of the rat brain during feeding, fasting, and diabetes
    • Lavrentyev EN, Matta SG, Cook GA. 2004. Expression of three carnitine palmitoyltransferase-I isoforms in 10 regions of the rat brain during feeding, fasting, and diabetes. Biochem Biophys Res Commun 315:174-8.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 174-178
    • Lavrentyev, E.N.1    Matta, S.G.2    Cook, G.A.3
  • 27
    • 0035865496 scopus 로고    scopus 로고
    • Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome- proliferator-activated receptor alpha (PPARalpha)-independent pathway
    • Louet JF, Chatelain F, Decaux JF, Park EA, Kohl C, Pineau T, Girard J, Pegorier JP. 2001. Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome- proliferator-activated receptor alpha (PPARalpha)-independent pathway. Biochem J 354:189-97.
    • (2001) Biochem J , vol.354 , pp. 189-197
    • Louet, J.F.1    Chatelain, F.2    Decaux, J.F.3    Park, E.A.4    Kohl, C.5    Pineau, T.6    Girard, J.7    Pegorier, J.P.8
  • 29
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
    • McGarry JD, Brown NF. 1997. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur J Biochem 244:11-14.
    • (1997) Eur J Biochem , vol.244 , pp. 11-14
    • McGarry, J.D.1    Brown, N.F.2
  • 30
    • 0015240314 scopus 로고
    • The regulation of ketogenesis from oleic acid and the influence of antiketogenic agents
    • McGarry JD, Foster DW. 1971. The regulation of ketogenesis from oleic acid and the influence of antiketogenic agents. J Biol Chem 246:6247-53.
    • (1971) J Biol Chem , vol.246 , pp. 6247-6253
    • McGarry, J.D.1    Foster, D.W.2
  • 31
    • 0015918936 scopus 로고
    • The effects of starvation and refeeding on carbohydrate and lipid metabolism in vivo and in the perfused rat liver
    • McGarry JD, Meier JM, Foster DW. 1973. The effects of starvation and refeeding on carbohydrate and lipid metabolism in vivo and in the perfused rat liver. J Biol Chem 248:270-8.
    • (1973) J Biol Chem , vol.248 , pp. 270-278
    • McGarry, J.D.1    Meier, J.M.2    Foster, D.W.3
  • 32
    • 0018126246 scopus 로고
    • Characteristics of fatty acid oxidation in rat liver homogenates and the inhibitory effect of malonyl-CoA
    • McGarry JD, Mannaerts GP, Foster DW. 1978a. Characteristics of fatty acid oxidation in rat liver homogenates and the inhibitory effect of malonyl-CoA. Biochim Biophys Acta 530:305-13.
    • (1978) Biochim Biophys Acta , vol.530 , pp. 305-313
    • McGarry, J.D.1    Mannaerts, G.P.2    Foster, D.W.3
  • 34
    • 0018129113 scopus 로고
    • Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay
    • McGarry JD, Stark M, Foster DW. 1978c. Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay. J Biol Chem 253:8291-3.
    • (1978) J Biol Chem , vol.253 , pp. 8291-8293
    • McGarry, J.D.1    Stark, M.2    Foster, D.W.3
  • 35
    • 14744267691 scopus 로고    scopus 로고
    • Strategy for isolation, derivatization, chromatographic separation, and detection of carnitine and acylcarnitine
    • Minkler PE, Ingalls ST, Hoppel CL. 2005. Strategy for isolation, derivatization, chromatographic separation, and detection of carnitine and acylcarnitine. Anal Chem 77:1448-57.
    • (2005) Anal Chem , vol.77 , pp. 1448-1457
    • Minkler, P.E.1    Ingalls, S.T.2    Hoppel, C.L.3
  • 36
    • 33646062887 scopus 로고    scopus 로고
    • Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry
    • Minkler PE, Kerner J, Kasumov T, Parland W, Hoppel CL. 2006. Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry. Anal Biochem 352:24-32.
    • (2006) Anal Biochem , vol.352 , pp. 24-32
    • Minkler, P.E.1    Kerner, J.2    Kasumov, T.3    Parland, W.4    Hoppel, C.L.5
  • 38
    • 0026646565 scopus 로고
    • Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation
    • Orellana M, Fuentes O, Rosenbluth H, Lara M, Valdes E. 1992. Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation. FEBS Lett 310:193-96.
    • (1992) FEBS Lett , vol.310 , pp. 193-196
    • Orellana, M.1    Fuentes, O.2    Rosenbluth, H.3    Lara, M.4    Valdes, E.5
  • 39
    • 0029166078 scopus 로고
    • Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I
    • Park EA, Mynatt RL, Cook GA, Kashfi K. 1995. Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I. Biochem J 310:853-8.
    • (1995) Biochem J , vol.310 , pp. 853-858
    • Park, E.A.1    Mynatt, R.L.2    Cook, G.A.3    Kashfi, K.4
  • 41
    • 0020483684 scopus 로고
    • Sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo
    • Robinson N, Zammit VA. 1982. Sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo. Biochem J 206:177-9.
    • (1982) Biochem J , vol.206 , pp. 177-179
    • Robinson, N.1    Zammit, V.A.2
  • 42
    • 0018800384 scopus 로고
    • Rate-limiting steps in metabolic pathways
    • Rognstad R. 1978. Rate-limiting steps in metabolic pathways. J Biol Chem 254:1875-8.
    • (1978) J Biol Chem , vol.254 , pp. 1875-1878
    • Rognstad, R.1
  • 43
    • 0019465834 scopus 로고
    • Effects of fasting, adrenalectomy and streptozotocin-diabetes on sensitivity of hepatic carnitine acyltransferase to malonyl CoA
    • Saggerson ED, Carpenter CA. 1981. Effects of fasting, adrenalectomy and streptozotocin-diabetes on sensitivity of hepatic carnitine acyltransferase to malonyl CoA. FEBS Lett 129:225-8.
    • (1981) FEBS Lett , vol.129 , pp. 225-228
    • Saggerson, E.D.1    Carpenter, C.A.2
  • 44
    • 0027365446 scopus 로고
    • Regulation of mitochondrial 3-hydroxy-3-methylglutaryl coenzyme - A synthase protein by starvation, fat feeding, and diabetes
    • Serra D, Casals N, Asino G, Royo T, Ciudad CJ, Hegardt FG. 1993. Regulation of mitochondrial 3-hydroxy-3-methylglutaryl coenzyme - A synthase protein by starvation, fat feeding, and diabetes. Arch Biochem Biophys 307:40-5.
    • (1993) Arch Biochem Biophys , vol.307 , pp. 40-45
    • Serra, D.1    Casals, N.2    Asino, G.3    Royo, T.4    Ciudad, C.J.5    Hegardt, F.G.6
  • 45
    • 0023221166 scopus 로고
    • Effect of starvation and diabetes on the sensitivity of carnitine palmitoyltransferase I to inhibition by 4-hydroxyphenylglyoxylate
    • Stephens TW, Harris RA. 1987. Effect of starvation and diabetes on the sensitivity of carnitine palmitoyltransferase I to inhibition by 4-hydroxyphenylglyoxylate. Biochem J 243:405-12.
    • (1987) Biochem J , vol.243 , pp. 405-412
    • Stephens, T.W.1    Harris, R.A.2
  • 47
    • 0022207618 scopus 로고
    • Extraction of tissue long-chain acyl-CoA esters and measurement by reverse-phase high-performance liquid chromatography
    • Woldegiorgis G, Spennetta T, Corkey BE, Williamson JR, Shrago E. 1985. Extraction of tissue long-chain acyl-CoA esters and measurement by reverse-phase high-performance liquid chromatography. Anal Biochem 150:8-12.
    • (1985) Anal Biochem , vol.150 , pp. 8-12
    • Woldegiorgis, G.1    Spennetta, T.2    Corkey, B.E.3    Williamson, J.R.4    Shrago, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.