Hydrogel-based nanocomposites and mesenchymal stem cells: A promising synergistic strategy for neurodegenerative disorders therapy

The Scientific World Journal

Volumn 2013, Issue , 2013, Pages

  Albani, Diego ^a   Gloria, Antonio ^b   Giordano, Carmen ^c   Rodilossi, Serena ^a   Russo, Teresa ^b   D'Amora, Ugo ^b   Tunesi, Marta ^c   Cigada, Alberto ^c   Ambrosio, Luigi ^b   Forloni, Gianluigi ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b CNR   (Italy)

^c POLITECNICO DI MILANO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; HORSERADISH PEROXIDASE; HYALURONIC ACID; HYDROGEN PEROXIDE; MATRIX METALLOPROTEINASE; NANOCOMPOSITE; POLYMACON; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; BIOMATERIAL;

ALZHEIMER DISEASE; BLOOD RHEOLOGY; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; FLOW MEASUREMENT; HUMAN; HYDRAULIC PERMEABILITY; HYDROGEL; IN VIVO STUDY; MESENCHYMAL STEM CELL; NERVE FIBER; NERVE REGENERATION; NERVOUS TISSUE; NEURAL STEM CELL; NEUROFILAMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGOCYTOSIS; REVIEW; YOUNG MODULUS; ANIMAL; CHEMISTRY; ELASTICITY; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; PATHOLOGY;

ANIMALS; BIOCOMPATIBLE MATERIALS; ELASTICITY; HUMANS; HYDROGELS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; NANOCOMPOSITES; NEURODEGENERATIVE DISEASES;

EID: 84896379852     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2013/270260     Document Type: Review

References (55)

1. Goya R. L., Kuan W., Barker R. A., The future of cell therapies in the treatment of Parkinson's disease. Expert Opinion on Biological Therapy 2007 7 10 1487 1498 2-s2.0-35348920028 10.1517/14712598.7.10.1487 (Pubitemid 47597138)
2. Payne N., Siatskas C., Barnard A., Bernard C. C. A., The prospect of stem cells as multi-faceted purveyors of immune modulation, repair and regeneration in multiple sclerosis. Current Stem Cell Research and Therapy 2011 6 1 50 62 2-s2.0-79551656899 10.2174/157488811794480735
3. Dadon-Nachum M., Melamed E., Offen D., Stem cells treatment for sciatic nerve injury. Expert Opinion on Biological Therapy 2011 11 12 1591 1597 2-s2.0-80555127347 10.1517/14712598.2011.628933
4. Giordano C., Albani D., Gloria A., Tunesi M., Batelli S., Russo T., Forloni G., Ambrosio L., Cigada A., Multidisciplinary perspectives for Alzheimer's and Parkinson's diseases: hydrogels for protein delivery and cell-based drug delivery as therapeutic strategies. International Journal of Artificial Organs 2009 32 12 836 850 2-s2.0-74349090263
5. Giordano C., Albani D., Gloria A., Tunesi M., Rodilossi S., Russo T., Forloni G., Ambrosio L., Cigada A., Nanocomposites for neurodegenerative diseases: hydrogel-nanoparticle combinations for a challenging drug delivery. International Journal of Artificial Organs 2011 34 12 1115 1127 2-s2.0-84455195432 10.5301/ijao.2011.8915
6. Munarin F., Petrini P., Bozzini S., Tanzi M. C., New perspectives in cell delivery systems for tissue regeneration: natural-derived injectable hydrogels. Journal of Applied Biomaterials & Functional Materials 2012 10 2 67 81
7. Tartivel L., Behl M., Schroeter M., Lendlein A., Hydrogel networks based on ABA triblock copolymers. Journal of Applied Biomaterials & Functional Materials 2012 10 3 243 248
8. Cirillo V., Guarino V., Ambrosio L., Design of bioactive electrospun scaffolds for bone tissue engineering. Journal of Applied Biomaterials & Functional Materials 2012 10 3 223 228
9. Pescosolido L., Miatto S., Di Meo C., Cencetti C., Coviello T., Alhaique F., Matricardi P., Injectable and in situ gelling hydrogels for modified protein release. European Biophysics Journal 2010 39 6 903 909 2-s2.0-77952097669 10.1007/s00249-009-0440-2
10. Li X., Katsanevakis E., Liu X., Zhang N., Wen X., Engineering neural stem cell fates with hydrogel design for central nervous system regeneration. Progress in Polymer Science 2012 37 8 1105 1129 2-s2.0-84859219975 10.1016/j.progpolymsci.2012.02.004
11. Michalek A. J., Buckley M. R., Bonassar L. J., Cohen I., Iatridis J. C., The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus. Spine Journal 2010 10 12 1098 1105 2-s2.0-78649279988 10.1016/j.spinee.2010.09.015
12. Martin J. T., Gorth D. J., Beattie E. E., Harfe B. D., Smith L. J., Elliott D. M., Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of intervertebral disc degeneration. Journal of Orthopaedic Research 2013 31 8 1276 1282
13. Singh K., Masuda K., An H. S., Animal models for human disc degeneration. Spine Journal 2005 5 6 supplement 267S 279S 2-s2.0-28244497107 10.1016/j.spinee.2005.02.016 (Pubitemid 41700071)
14. Silva-Correia J., Miranda-Gonçalves V., Salgado A. J., Angiogenic potential of gellan-gum-based hydrogels for application in nucleus pulposus regeneration: in vivo study. Tissue Engineering A 2012 18 11-12 1203 1212
15. Benz K., Stippich C., Osswald C., Gaissmaier C., Lembert N., Badke A., Steck E., Aicher W. K., Mollenhauer J. A., Rheological and biological properties of a hydrogel support for cells intended for intervertebral disc repair. BMC Musculoskeletal Disorders 2012 13, article 54 2-s2.0-84859480315 10.1186/1471-2474-13-54
16. Reitmaier S., Wolfram U., Ignatius A., Hydrogels for nucleus replacement: facing the biomechanical challenge. Journal of the Mechanical Behavior of Biomedical Materials 2012 14 67 77
17. Jansen K. A., Bacabac R. G., Piechocka I. K., Koenderink G. H., Cells actively stiffen fibrin networks by generating contractile stress. Biophysical Journal 2013 105 10 2240 2251
18. Galie P. A., Stegemann J. P., Simultaneous application of interstitial flow and cyclic mechanical strain to a three-dimensional cell-seeded hydrogel. Tissue Engineering C 2011 17 5 527 536 2-s2.0-79955446671 10.1089/ten.tec.2010. 0547
19. Kesselman D., Kossover O., Mironi-Harpaz I., Seliktar D., Time-dependent cellular morphogenesis and matrix stiffening in proteolytically responsive hydrogels. Acta Biomaterials 2013 9 8 7630 7639
20. Silva-Correia J., Gloria A., Oliveira M. B., Rheological and mechanical properties of acellular and cell-laden methacrylated gellan gum hydrogels. Journal of Biomedical Materials Research A 2013 101 12 3438 3446
21. Russo T., D'Amora U., Gloria A., Systematic analysis of injectable materials and 3D rapid prototyped magnetic scaffolds: from CNS applications to soft and hard tissue repair/regeneration. Procedia Engineering 2013 59 233 239
22. Gloria A., Borzacchiello A., Causa F., Ambrosio L., Rheological characterization of hyaluronic acid derivatives as injectable materials toward nucleus pulposus regeneration. Journal of Biomaterials Applications 2012 26 6 745 759 2-s2.0-84856304727 10.1177/0885328210387174
23. Nicolais L., Gloria A., Ambrosio L., Ambrosio L., The mechanics of biocomposites. Biomedical Composites 2010 London, UK CRC Press 411 440
24. Fischer H., Polymer nanocomposites: from fundamental research to specific applications. Materials Science and Engineering C 2003 23 6-8 763 772 2-s2.0-0345118962 10.1016/j.msec.2003.09.148 (Pubitemid 37507272)
25. Borzacchiello A., Gloria A., Mayol L., Dickinson S., Miot S., Martin I., Ambrosio L., Natural/synthetic porous scaffold designs and properties for fibro-cartilaginous tissue engineering. Journal of Bioactive and Compatible Polymers 2011 26 5 437 451 2-s2.0-80052739214 10.1177/0883911511420149
26. Koudehi M. F., Fooladi A. A., Mansoori K., Jamalpoor Z., Amiri A., Nourani M. R., Preparation and evaluation of novel nano-bioglass/gelatin conduit for peripheral nerve regeneration. Journal of Materials Science 2013 10.1007/s10856-013-5076-1
27. Rides M., Allen C. R. G., Sims G. D., Rheological characterisation of a highly filled curing system using a disposable extrusion rheometer. Polymer Testing 2010 29 2 164 169 2-s2.0-75749108845 10.1016/j.polymertesting.2009.10. 006
28. Collyer A. A., Clegg D. W., Rheological Measurement 1998 London, UK Chapman & Hall
29. Ateshian G. A., Warden W. H., Kim J. J., Grelsamer R. P., Mow V. C., Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments. Journal of Biomechanics 1997 30 11-12 1157 1164 2-s2.0-0031279438 10.1016/S0021-9290(97)85606-0 (Pubitemid 28032473)
30. Williamson A. K., Chen A. C., Sah R. L., Compressive properties and function-composition relationships of developing bovine articular cartilage. Journal of Orthopaedic Research 2001 19 6 1113 1121 2-s2.0-0035216630 10.1016/S0736-0266(01)00052-3 (Pubitemid 33150189)
31. Holmes M. H., Mow V. C., The nonlinear characteristics of soft gels and hydrated connective tissus in ultrafiltration. Journal of Biomechanics 1990 23 11 1145 1156 2-s2.0-0025241673 10.1016/0021-9290(90)90007-P
32. Freudenberg U., Hermann A., Welzel P. B., Stirl K., Schwarz S. C., Grimmer M., Zieris A., Panyanuwat W., Zschoche S., Meinhold D., Storch A., Werner C., A star-PEG-heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases. Biomaterials 2009 30 28 5049 5060 2-s2.0-67849094098 10.1016/j.biomaterials.2009.06.002
33. Mooney R., Haeger S., Lawal R., Mason M., Shrestha N., Laperle A., Bjugstad K., Mahoney M., Control of neural cell composition in poly(ethylene glycol) hydrogel culture with soluble factors. Tissue Engineering A 2011 17 21-22 2805 2815 2-s2.0-80155149906 10.1089/ten.tea.2010.0654
34. Zhou Z., Yu P., Geller H. M., Ober C. K., The role of hydrogels with tethered acetylcholine functionality on the adhesion and viability of hippocampal neurons and glial cells. Biomaterials 2012 33 8 2473 2481 2-s2.0-84855858023 10.1016/j.biomaterials.2011.12.005
35. Lindvall O., Kokaia Z., Martinez-Serrano A., Stem cell therapy for human neurodegenerative disorders-how to make it work. Nature Medicine 2004 10 supplement S42 S50 2-s2.0-3142521479 10.1038/nm1064 (Pubitemid 38901866)
36. Ghoreishian M., Rezaei M., Beni B. H., Javanmard S. H., Attar B. M., Zalzali H., Facial nerve repair with Gore-Tex tube and adipose-derived stem cells: an animal study in dogs. Journal of Oral and Maxillofacial Surgery 2013 71 3 577 587
37. Kubinová A. Š., Horák D., Hejčl A., Plichta Z., Kotek J., Syková E., Highly superporous cholesterol-modified poly(2-hydroxyethyl methacrylate) scaffolds for spinal cord injury repair. Journal of Biomedical Materials Research A 2011 99 4 618 629 2-s2.0-80255132113 10.1002/jbm.a.33221
38. Perale G., Giordano C., Bianco F., Rossi F., Tunesi M., Daniele F., Crivelli F., Matteoli M., Masi M., Hydrogel for cell housing in the brain and in the spinal cord. International Journal of Artificial Organs 2011 34 3 295 303 2-s2.0-79955736661 10.5301/IJAO.2011.6488
39. Gu H., Yue Z., Leong W. S., Nugraha B., Tan L. P., Control of in vitro neural differentiation of mesenchymal stem cells in 3D macroporous, cellulosic hydrogels. Regenerative Medicine 2010 5 2 245 253 2-s2.0-77949368511 10.2217/rme.09.89
40. Wang L., Chung J. E., Chan P., Kurisawa M., Injectable biodegradable hydrogels with tunable mechanical properties for the stimulation of neurogenesic differentiation of human mesenchymal stem cells in 3D culture. Biomaterials 2010 31 6 1148 1157 2-s2.0-72449191201 10.1016/j.biomaterials.2009.10.042
41. Hejčl A., Šedý J., Kapcalová M., Toro D. A., Amemori T., Lesný P., Likavčanová- Mašínová K., Krumbholcová E., Přá dný M., Michálek J., Burian M., Hájek M., Jendelová P., Syková E., HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic spinal cord injury. Stem Cells and Development 2010 19 10 1535 1546 2-s2.0-77949655518 10.1089/scd.2009.0378
42. Park J., Lim E., Back S., Na H., Park Y., Sun K., Nerve regeneration following spinal cord injury using matrix metalloproteinase-sensitive, hyaluronic acid-based biomimetic hydrogel scaffold containing brain-derived neurotrophic factor. Journal of Biomedical Materials Research A 2010 93 3 1091 1099 2-s2.0-77950641715 10.1002/jbm.a.32519
43. Sykové E., Jendelová P., Migration, fate and in vivo imaging of adult stem cells in the CNS. Cell Death and Differentiation 2007 14 7 1336 1342 2-s2.0-34250747913 10.1038/sj.cdd.4402140 (Pubitemid 46965263)
44. Zeng G., Wang G., Guan F., Chang K., Jiao H., Gao W., Xi S., Yang B., Human amniotic membrane-derived mesenchymal stem cells labeled with superparamagnetic iron oxide nanoparticles: the effect on neuron-like differentiation in vitro. Molecular and Cellular Biochemistry 2011 357 1-2 331 341 2-s2.0-84857384962
45. Jae K. L., Man K. L., Hye J. J., Kim D., Yoon S. Y., Oh W., Yang S., Tae S. P., Soo Y. L., Kim B., Jeun S., Efficient intracytoplasmic labeling of human umbilical cord blood mesenchymal stromal cells with ferumoxides. Cell Transplantation 2007 16 8 849 857 2-s2.0-41349104676 (Pubitemid 351448260)
46. Lee J. K., Schuchman E. H., Jin H. K., Bae J. S., Soluble CCL5 derived from bone marrow-derived mesenchymal stem cells and activated by amyloid β ameliorates Alzheimer's disease in mice by recruiting bone marrow-induced microglia immune responses. Stem Cells 2012 30 7 1544 1555
47. Kim J.-Y., Kim D. H., Kim J. H., Lee D., Jeon H. B., Kwon S.-J., Kim S. M., Yoo Y. J., Lee E. H., Choi S. J., Seo S. W., Lee J. I., Na D. L., Yang Y. S., Oh W., Chang J. W., Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid- Β plaques. Cell Death and Differentiation 2012 19 4 680 691 2-s2.0-84858158543 10.1038/cdd.2011.140
48. Whone A. L., Kemp K., Sun M., Wilkins A., Scolding N. J., Human bone marrow mesenchymal stem cells protect catecholaminergic and serotonergic neuronal perikarya and transporter function from oxidative stress by the secretion of glial-derived neurotrophic factor. Brain Research 2012 1431 86 96 2-s2.0-84855682242 10.1016/j.brainres.2011.10.038
49. Caicco M. J., Cooke M. J., Wang Y., Tuladhar A., Morshead C. M., Shoichet M. S., A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke. Journal of Controlled Release 2013 166 3 197 202
50. Albani D., Peverelli E., Rametta R., Batelli S., Veschini L., Negro A., Forloni G., Protective effect of TAT-delivered α -synuclein: relevance of the C-terminal domain and involvement of HSP70. The FASEB Journal 2004 18 14 1713 1715 2-s2.0-9444272812 10.1096/fj.04-1621fje (Pubitemid 39561660)
51. Batelli S., Albani D., Rametta R., Polito L., Prato F., Pesaresi M., Negro A., Forloni G., DJ-1 modulates α -synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70. PLoS ONE 2008 3 4 2-s2.0-44849093321 10.1371/journal.pone. 0001884 e1884 (Pubitemid 351943824)
52. Jinwal U. K., Akoury E., Abisambra J. F., Imbalance of Hsp70 family variants fosters tau accumulation. The FASEB Journal 2013 27 4 1450 1459
53. Cui J., Wang Y., Dong Q., Wu S., Xiao X., Hu J., Chai Z., Zhang Y., Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70. Journal of Neuroscience 2011 31 45 16227 16240 2-s2.0-80755168028 10.1523/JNEUROSCI.3915-11.2011
54. Baino F., Fiorilli S., Mortera R., Mesoporous bioactive glass as a multifunctional system for bone regeneration and controlled drug release. Journal of Applied Biomaterials & Functional Materials 2012 1 10 12 21
55. Venkataramana N. K., Pal R., Rao S. A. V., Naik A. L., Jan M., Nair R., Sanjeev C. C., Kamble R. B., Murthy D. P., Chaitanya K., Bilateral transplantation of allogenic adult human bone marrow-derived mesenchymal stem cells into the subventricular zone of Parkinson's disease: a pilot clinical study. Stem Cells International 2012 2012 12 2-s2.0-84859786092 10.1155/2012/931902 931902