Design of bioactive electrospun scaffolds for bone tissue engineering

Journal of Applied Biomaterials and Functional Materials

Volumn 10, Issue 3, 2012, Pages 223-228

  Cirillo, Valentina ^a   Guarino, Vincenzo ^a   Ambrosio, Luigi ^a  

^a CNR   (Italy)

Author keywords

Bilayered structures; Bone regeneration; Electrospinning; Flat membranes; Gelatin; Polycaprolactone

Indexed keywords

BONE; MECHANICAL STABILITY; POLYCAPROLACTONE; SCAFFOLDS (BIOLOGY); TISSUE REGENERATION;

BI-LAYERED STRUCTURE; BILAYERED; BIOACTIVES; BONE REGENERATION; BONE TISSUE ENGINEERING; ELECTROSPUN SCAFFOLDS; FIBROUS SCAFFOLDS; FLAT MEMBRANE; GELATIN; NATURAL TISSUES;

ELECTROSPINNING;

GELATIN; POLYCAPROLACTONE; POLYMER; TISSUE SCAFFOLD;

ARTICLE; BILAYER MEMBRANE; BIOLOGICAL ACTIVITY; BONE REGENERATION; CHEMICAL STRUCTURE; COMPOSITE MATERIAL; ELECTROSPINNING; EXTRACELLULAR MATRIX; FIBER; MOLECULAR STABILITY; NANOBIOTECHNOLOGY; SOLVENT EFFECT; SYNTHESIS; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING;

EID: 84874259870     PISSN: None     EISSN: 22808000     Source Type: Journal    
DOI: 10.5301/JABFM.2012.10343     Document Type: Article

References (34)

1. Gupta D, Venugopal J, Mitra S, Giri Dev VR, Ramakrishna S. Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts. Biomaterials. 2009;30:2085-2094.
2. Song J, Bertozzi CR. Functional polymers for bone tissue engineering applications. In: Hari Singh Nalwa, ed. Handbook of nanostructured biomaterials and their applications in nanobiotechnology. J Nanosci Nanotechnol. USA: American Scienific Publishers 2005; vol 2: 371-392.
3. Kokubo T, Kim HM, Kawashita M. Novel bioactive materials with different mechanical properties. Biomaterials. 2003;24:2161-2165.
4. Guarino V, Lewandowska M, Bil M, Polak B, Ambrosio L. Morphology and degradation properties of PCL/HYAFF11 composite scaffolds with multi-scale degradation rate. Compos Sci Technol. 2010;70:1826-1837.
5. Bishop A, Balàzsi C, Yang JH, Gouma PI. Biopolymerhydroxyapatite composite coatings prepared by electrospinning. Polym Adv Technol. 2006;17:902-906.
6. Borriello A, Guarino V, Schiavo L, Alvarez-Perez MA, Ambrosio L. Optimizing PANi doped electroactive substrates as patches for the regeneration of cardiac muscle. J Mater Sci Mater Med. 2011;22:1053-1062.
7. Sharma B, Elisseeff JH. Engineering structurally organized cartilage and bone tissues. Ann Biomed Eng. 2004;32:148-159.
8. Mastrogiacomo M, Muraglia A, Komlev V, et al. Tissue engineering of bone: search for a better scaffold. Orthod Craniofac Res. 2005;8(4):277-284.
9. Guarino V, Alvarez-Perez MA, Cirillo V, Ambrosio L. hMSC interaction with PCL and PCL/gelatin platforms: a comparative study on films and electrospun membranes. J Bioact Comp Pol. 2011;26(2):144-160.
10. Lavenus S, Pilet P, Guicheux J, Weiss P, Louarn G, Layrolle P. Behaviour of mesenchymal stem cells, fibroblasts and osteoblasts on smooth surfaces. Acta Biomater. 2011;7(4):1525-1534.
11. Guarino V, Cirillo V, Taddei P, Alvarez-Perez MA, Ambrosio L. Tuning size scale and crystallinity of PCL electrospun fibres via solvent permittivity to address hMSC response. Macromol Biosci. 2011;11(12):1694-1705.
12. Shields KJ, Beckman MJ, Bowlin GL, Wayne JS. Mechanical properties and cellular proliferation of electrospun collagen type II. Tissue Eng. 2004;10:1510-1517.
13. Telemeco TA, Ayres C, Bowlin GL, et al. Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning. Acta Biomater. 2005;1:377-385.
14. Huang L, Nagapudi K, Apkarian RP, Chaikof EL. Engineered collagen-PEO nanofibers and fabrics. J Biomater Sci Polym. 2001;12(9):979-993.
15. Tampieri A, Sandri M, Landi E, et al. Design of graded biomimetic osteochondral composite scaffolds. Biomaterials. 2008;29:3539-3546.
16. Papenburg BJ, Liu J, Higuera GA, et al. Development and analysis of multilayer scaffolds for tissue engineering. Biomaterials. 2009;30(31):6228-6239.
17. Guarino V, Causa F, Salerno A, Ambrosio L, Netti PA. Design and manufacture of microporous polymeric materials with hierarchal complex structure for biomedical application. Mater Sci Technol. 2008;24:1111-1117.
18. Guarino V, Causa F, Taddei P, et al. Polylactic acid fibrereinforced polycaprolactone scaffolds for bone tissue engineering. Biomaterials. 2008;29:3662-3670.
19. Guaccio A, Guarino V, Alvarez-Perez MA, Cirillo V, Netti PA, Ambrosio L. Influence of electrospun fiber mesh size on hMSC oxygen metabolism in 3D collagen matrices: experimental and theoretical evidences. Biotechnol Bioeng. 2011;108(8):1965-1976.
20. Liu X, Smith LA, Hu J, Maa PX. Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering. Biomaterials. 2009;30:2252-2258.
21. Abrams GA, Goodman SL, Nealey PF, Franco M, Murphy CJ. Nanoscale topography of the basement membrane underlying the corneal epithelium of the rhesus macaque. Cell Tissue Res. 2000;209:39-46.
22. Flemming RG, Murphy CJ, Abrams GA, Goodman SL, Nealey PF. Effect of synthetic micro and nanostructured surfaces on cell behaviour. Biomaterials. 1999;20:573-588.
23. Maniglio D, Bonani W, Bortoluzzi G, Servoli E, Motta A, Migliaresi CA. Electrodeposition of silk fibroin on metal substrates. J Bioact Compat Polym. 2010;25:441-454.
24. Liao S, Chan CK, Ramakrishna S. Electrospun nanofibers: work for medicine? Front Mater Sci China. 2010;4(1):29-33.
25. Kadler KE, Holmes DF, Trotter JA, Chapman JA. Collagen fibril formation. Biochem J. 1996;316:1-11.
26. Harrington WF, Vonhippel PH. The structure of collagen and gelatin. Adv Protein Chem. 1961;16:1-138.
27. Kang HW, Tabata Y, Ikada Y. Fabrication of porous gelatin scaffolds for tissue engineering. Biomaterials. 1999;20:1339-1344.
28. Alvarez-Perez MA, Guarino V, Cirillo V, Ambrosio L. Influence of gelatin cues in PCL electrospun membranes on nerve outgrowth. Biomacromolecules. 2010;11(9):2238-2246.
29. Zeugolis DI, Khew ST, Yew ES, et al. Electro-spinning of pure collagen nano-fibres: just an expensive way to make gelatin? Biomaterials. 2008;29:2293-2305.
30. Zang S, Huang Y, Yang X, et al. Gelatin nanofibrous membrane fabricated by electrospinning of aqueous gelatin solution for guided tissue regeneration. J Biomed Mater Res Part A. 2009;90:671-679.
31. Guarino V, Taddei P, Di Foggia M, Fagnano C, Ciapetti G, Ambrosio L. The influence of hydroxyapatite particles on in vitro degradation behavior of poly e-caprolactone-based composite scaffolds. Tissue Eng Part A. 2009;15(11):3655-3668.
32. Alvarez Perez MA, Guarino V, Cirillo V, Ambrosio L. In vitro mineralization and bone osteogenesis in poly(ε-caprolactone)/gelatin nanofibers. J Biomed Mater Res Part A. 2012;100(11):3008-3019 DOI:10.1002/jbm.a.34233.
33. Guarino V, Guaccio A, Ambrosio L. Manipulating cocontinuous polymer blends to create PCL scaffolds with fully interconnected and anisotropic pore architecture. J Appl Biomater Biomech. 2011;9(1):34-39.
34. Agarwal S, Wendorff JH, Greiner A. Use of electrospinning technique for biomedical applications. Polymer. 2008;49(26):5603-5621.