-
1
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001; 107: 137-48.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
-
2
-
-
0035913903
-
hsir2 (SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng Eaton E et al. hsir2 (SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001; 107: 149-59.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
-
3
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303: 2011-5.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
4
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305: 390-2.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
-
5
-
-
0242322010
-
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF) -interacting protein 2-mediated transcriptional repression
-
Senawong T, Peterson VJ, Avram D et al. Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF) -interacting protein 2-mediated transcriptional repression. J. Biol. Chem. 2003; 278: 041-50.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 041-50
-
-
Senawong, T.1
Peterson, V.J.2
Avram, D.3
-
6
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol. Cell 2007; 28: 91-106.
-
(2007)
Mol. Cell
, vol.28
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
7
-
-
33750367457
-
Hormonal control of androgen receptor function through SIRT1
-
Fu M, Liu M, Sauve AA et al. Hormonal control of androgen receptor function through SIRT1. Mol. Cell. Biol. 2006; 26: 8122-35.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8122-8135
-
-
Fu, M.1
Liu, M.2
Sauve, A.A.3
-
8
-
-
77951211562
-
SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages
-
Zhang R, Chen HZ, Liu JJ et al. SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. J. Biol. Chem. 2010; 285: 7097-110.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7097-7110
-
-
Zhang, R.1
Chen, H.Z.2
Liu, J.J.3
-
9
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 2004; 23: 2369-80.
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
-
10
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005; 434: 113-8.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
11
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
Nemoto S, Fergusson MM, Finkel T. SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J. Biol. Chem. 2005; 280: 456-60.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 456-460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
12
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000; 289: 2126-8.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
13
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410: 227-30.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
14
-
-
0030466371
-
The retardation of aging by caloric restriction: Studies in rodents and primates
-
Weindruch R. The retardation of aging by caloric restriction: Studies in rodents and primates. Toxicol. Pathol. 1996; 24: 742-5.
-
(1996)
Toxicol. Pathol.
, vol.24
, pp. 742-745
-
-
Weindruch, R.1
-
15
-
-
77949539030
-
JNK1 phosphorylates SIRT1 and promotes its enzymatic activity
-
Nasrin N, Kaushik VK, Fortier E et al. JNK1 phosphorylates SIRT1 and promotes its enzymatic activity. PLoS ONE 2009; 4: e8414.
-
(2009)
PLoS ONE
, vol.4
-
-
Nasrin, N.1
Kaushik, V.K.2
Fortier, E.3
-
16
-
-
35748962613
-
SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
-
Yang Y, Fu W, Chen J et al. SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress. Nat. Cell Biol. 2007; 9: 1253-62.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1253-1262
-
-
Yang, Y.1
Fu, W.2
Chen, J.3
-
17
-
-
79959355078
-
Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity
-
Gao Z, Zhang J, Kheterpal I, Kennedy N, Davis RJ, Ye J. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. J. Biol. Chem. 2011; 286: 22227-34.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22227-22234
-
-
Gao, Z.1
Zhang, J.2
Kheterpal, I.3
Kennedy, N.4
Davis, R.J.5
Ye, J.6
-
18
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis MC, Sinclair DA. Mammalian sirtuins: Biological insights and disease relevance. Annu. Rev. Pathol. 2010; 5: 253-95.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
19
-
-
84861461517
-
USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development
-
Lin Z, Yang H, Kong Q et al. USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development. Mol. Cell 2012; 46: 484-94.
-
(2012)
Mol. Cell
, vol.46
, pp. 484-494
-
-
Lin, Z.1
Yang, H.2
Kong, Q.3
-
21
-
-
53649100104
-
JNK2-dependent regulation of SIRT1 protein stability
-
Ford J, Ahmed S, Allison S, Jiang M, Milner J. JNK2-dependent regulation of SIRT1 protein stability. Cell Cycle 2008; 7: 3091-7.
-
(2008)
Cell Cycle
, vol.7
, pp. 3091-3097
-
-
Ford, J.1
Ahmed, S.2
Allison, S.3
Jiang, M.4
Milner, J.5
-
22
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004; 306: 2105-8.
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
23
-
-
33846505019
-
Metabolic regulation of SIRT1 transcription via a HIC1: CtBP corepressor complex
-
Zhang Q, Wang SY, Fleuriel C et al. Metabolic regulation of SIRT1 transcription via a HIC1: CtBP corepressor complex. Proc. Natl Acad. Sci. USA 2007; 104: 829-33.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 829-833
-
-
Zhang, Q.1
Wang, S.Y.2
Fleuriel, C.3
-
24
-
-
33748200050
-
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
-
Wang C, Chen L, Hou X et al. Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat. Cell Biol. 2006; 8: 1025-31.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1025-1031
-
-
Wang, C.1
Chen, L.2
Hou, X.3
-
25
-
-
65349096174
-
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation
-
Yuan J, Minter-Dykhouse K, Lou Z. A c-Myc-SIRT1 feedback loop regulates cell growth and transformation. J. Cell Biol. 2009; 185: 203-11.
-
(2009)
J. Cell Biol.
, vol.185
, pp. 203-211
-
-
Yuan, J.1
Minter-Dykhouse, K.2
Lou, Z.3
-
27
-
-
65249185780
-
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes
-
Rane S, He M, Sayed D et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ. Res. 2009; 104: 879-86.
-
(2009)
Circ. Res.
, vol.104
, pp. 879-886
-
-
Rane, S.1
He, M.2
Sayed, D.3
|