GS 455534 selectively suppresses binge eating of palatable food and attenuates dopamine release in the accumbens of sugar-bingeing rats

Behavioural Pharmacology

Volumn 25, Issue 2, 2014, Pages 147-157

  Bocarsly, Miriam E ^a   Hoebel, Bartley G ^a   Paredes, Daniel ^b   Von Loga, Isabell ^a   Murray, Susan M ^a,c   Wang, Miaoyuan ^c   Arolfo, Maria P ^d   Yao, Lina ^d   Diamond, Ivan ^d   Avena, Nicole M ^a,c,e  

^a PRINCETON UNIVERSITY   (United States)

^b LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d Gilead Sciences   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

addiction; aldehyde dehydrogenase 2 inhibitors; binge eating; dopamine; rat

Indexed keywords

ALDEHYDE DEHYDROGENASE INHIBITOR; DOPAMINE; GS 455534; UNCLASSIFIED DRUG; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, RAT; CVT-10216; ENZYME INHIBITOR; FAT INTAKE; ISOFLAVONE DERIVATIVE; MITOCHONDRIAL PROTEIN; SUGAR INTAKE;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINGE EATING DISORDER; COCAINE DEPENDENCE; CONTROLLED STUDY; DIALYSATE; DOPAMINE RELEASE; DRUG EFFECT; DRUG SELECTIVITY; FOOD INTAKE; MALE; MICRODIALYSIS; NEUROCHEMISTRY; NONHUMAN; NUCLEUS ACCUMBENS; PALATABILITY; RAT; SUGAR INTAKE; ANIMAL; ANTAGONISTS AND INHIBITORS; BODY WEIGHT; BULIMIA; DOSE RESPONSE; DRUG EFFECTS; EATING; FAT INTAKE; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ALDEHYDE DEHYDROGENASE; ANIMALS; APPETITE REGULATION; BODY WEIGHT; BULIMIA; DIETARY FATS; DIETARY SUCROSE; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENZYME INHIBITORS; ISOFLAVONES; MALE; MITOCHONDRIAL PROTEINS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84896324417     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0000000000000029     Document Type: Article

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