Animal models of sugar and fat bingeing: Relationship to food addiction and increased body weight

Methods in Molecular Biology

Volumn 829, Issue , 2012, Pages 351-365

  Avena, Nicole M ^a   Bocarsly, Miriam E ^b   Hoebel, Bartley G ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

Binge eating; Body weight; Dopamine; Fat; Food addiction; Nucleus accumbens; Sugar

Indexed keywords

DOPAMINE;

ADDICTION; ANIMAL; ANIMAL BEHAVIOR; ARTICLE; BINGE EATING DISORDER; BIOSYNTHESIS; BULIMIA; CALORIC INTAKE; CARBOHYDRATE DIET; DISEASE MODEL; FAT INTAKE; FEEDING BEHAVIOR; FEMALE; FOOD; MALE; METABOLISM; NUCLEUS ACCUMBENS; OBESITY; PATHOLOGY; PHYSIOLOGY; RAT; SECRETION; SPRAGUE DAWLEY RAT; WEIGHT GAIN; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; BINGE-EATING DISORDER; BULIMIA; DIETARY CARBOHYDRATES; DIETARY FATS; DISEASE MODELS, ANIMAL; DOPAMINE; ENERGY INTAKE; FEEDING BEHAVIOR; FEMALE; FOOD; MALE; NUCLEUS ACCUMBENS; OBESITY; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS; WEIGHT GAIN;

ANIMALIA; RATTUS;

EID: 84856331369     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-458-2_23     Document Type: Article

References (63)

1. Hudson, J. I.; Hiripi, E.; Pope, H. G.; Jr.; Kessler, R. C. (2007) The prevalence and correlates of eating disorders in the national comorbidity survey replication. Biol Psychiatry 61, 348-58. (Pubitemid 46108682)
2. Ogden, C. L.; Yanovski, S. Z.; Carroll, M. D.; Flegal, K. M. (2007) The epidemiology of obesity. Gastroenterology 132, 2087-102. (Pubitemid 46693751)
3. Stunkard, A. J. (1959) Eating patterns and obesity. Psychiatr Q 33, 284-95.
4. Tanofsky-Kraff, M.; Cohen, M. L.; Yanovski, S. Z.; Cox, C.; Theim, K. R.; Keil, M.; Reynolds, J. C.; Yanovski, J. A. (2006) A prospective study of psychological predictors of body fat gain among children at high risk for adult obesity. Pediatrics 117, 1203-9. (Pubitemid 46071513)
5. Ramacciotti, C. E.; Coli, E.; Paoli, R.; Gabriellini, G.; Schulte, F.; Castrogiovanni, S.; DellOsso, L.; Garfi nkel, P. E. (2005) The relationship between binge eating disorder and non-purging bulimia nervosa. Eat Weight Disord 10, 8-12. (Pubitemid 43098411)
6. Grucza, R. A.; Przybeck, T. R.; Cloninger, C. R. (2007) Prevalence and correlates of binge eating disorder in a community sample. Compr Psychiatry 48, 124-31. (Pubitemid 46204665)
7. Galanti, K.; Gluck, M. E.; Geliebter, A. (2007) Test meal intake in obese binge eaters in relation to impulsivity and compulsivity. Int J Eat Disord 40, 727-32. (Pubitemid 350106962)
8. Yudkin, J. (1972) Sweet and Dangerous, Peter H. Wyden, Inc, New York.
9. Bray, G. A.; York, B.; DeLany, J. (1992) A survey of the opinions of obesity experts on the causes and treatment of obesity. Am J Clin Nutr 55, 151S-54S.
10. Bray, G. A.; Popkin, B. M. (1998) Dietary fat intake does affect obesity! Am J Clin Nutr 68, 1157-73. (Pubitemid 28550944)
11. Avena, N.; Rada, P.; Hoebel, B. (2006) Unit 9.23C Sugar bingeing in rats, in "Current Protocols in Neuroscience" (Crawley, J.; Gerfen, C.; Rogawski, M.; Sibley, D.; Skolnick, P.; Wray, S.; Eds.), John Wiley and Sons, Inc.; Indianapolis pp. 9.23C.1-9.23C.6.
12. Avena, N. M.; Rada, P.; Hoebel, B. G. (2008) Evidence of sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev 32, 20-39. (Pubitemid 350160955)
13. Hoebel, B. G. (1985) Brain neurotransmitters in food and drug reward. Am J Clin Nutr 42, 1133-50. (Pubitemid 16148065)
14. Hernandez, L.; Hoebel, B. G. (1988) Feeding and hypothalamic stimulation increase dopamine turnover in the accumbens. Physiol Behav 44, 599-606. (Pubitemid 19030123)
15. Kelley, A. E.; Bakshi, V. P.; Haber, S. N.; Steininger, T. L.; Will, M. J.; Zhang, M. (2002) Opioid modulation of taste hedonics within the ventral striatum. Physiol Behav 76, 365-77. (Pubitemid 34765590)
16. Le Magnen, J. (1990) A role for opiates in food reward and food addiction, in "Taste, Experience, and Feeding" (Capaldi, P. T.; Ed.), American Psychological Association, Washington, D. C. pp. 241-52.
17. Volkow, N. D.; Wise, R. A. (2005) How can drug addiction help us understand obesity? Nat Neurosci 8, 555-60. (Pubitemid 40594193)
18. Wise, R. A. (1989) Opiate reward: sites and substrates. Neurosci Biobehav Rev 13, 129-33. (Pubitemid 19241927)
19. Ahmed, S. H.; Koob, G. F. (1998) Transition from moderate to excessive drug intake: change in hedonic set point. Science 282, 298-300. (Pubitemid 28487203)
20. Heyser, C. J.; Schulteis, G.; Koob, G. F. (1997) Increased ethanol self-administration after a period of imposed ethanol deprivation in rats trained in a limited access paradigm. Alcohol Clin Exp Res 21, 784-91. (Pubitemid 27355674)
21. Avena, N. M.; Carrillo, C. A.; Needham, L.; Leibowitz, S. F.; Hoebel, B. G. (2004) Sugar-dependent rats show enhanced intake of unsweetened ethanol. Alcohol 34, 203-9. (Pubitemid 40292778)
22. Avena, N. M.; Hoebel, B. G. (2003) A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine. Neuroscience 122, 17-20. (Pubitemid 37329944)
23. Avena, N. M.; Hoebel, B. G. (2003) Amphetamine-sensitized rats show sugarinduced hyperactivity (cross-sensitization) and sugar hyperphagia. Pharmacol Biochem Behav 74, 635-9. (Pubitemid 36126541)
24. Colantuoni, C.; Rada, P.; McCarthy, J.; Patten, C.; Avena, N. M.; Chadeayne, A.; Hoebel, B. G. (2002) Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence. Obes Res 10, 478-88. (Pubitemid 135686640)
25. Colantuoni, C.; Schwenker, J.; McCarthy, J.; Rada, P.; Ladenheim, B.; Cadet, J. L.; Schwartz, G. J.; Moran, T. H.; Hoebel, B. G. (2001) Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain. Neuroreport 12, 3549-52. (Pubitemid 33065496)
26. Gosnell, B. A. (2005) Sucrose intake enhances behavioral sensitization produced by cocaine. Brain Res 1031, 194-201. (Pubitemid 40093072)
27. Grimm, J. W.; Fyall, A. M.; Osincup, D. P. (2005) Incubation of sucrose craving: effects of reduced training and sucrose pre-loading. Physiol Behav 84, 73-9. (Pubitemid 40092067)
28. Rada, P.; Avena, N. M.; Hoebel, B. G. (2005) Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience 134, 737-44. (Pubitemid 41133378)
29. Wideman, C. H.; Nadzam, G. R.; Murphy, H. M. (2005) Implications of an animal model of sugar addiction, withdrawal and relapse for human health. Nutr Neurosci 8, 269-76.
30. Spangler, R.; Wittkowski, K. M.; Goddard, N. L.; Avena, N. M.; Hoebel, B. G.; Leibowitz, S. F. (2004) Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Brain Res Mol Brain Res 124, 134-42. (Pubitemid 38591565)
31. Hernandez, L.; Hoebel, B. G. (1988) Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci 42, 1705-12.
32. Hoebel, B. G.; Hernandez, L.; Schwartz, D. H.; Mark, G. P.; Hunter, G. A. (1989) Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behavior: theoretical and clinical implications, in "The Psychobiology of Human Eating Disorders: Preclinical and Clinical Perspectives" (Schneider, L. H.; Cooper, S. J.; Halmi, K. A.; Eds.), Annals of the New York Academy of Sciences, New York. pp.171-91.
33. Koob, G. F. (1999) Drug reward and addiction, in "Fundamental Neuroscience" (Zigmond, M.; Bloom, F. E.; Landis, S. C.; Roberts, J. L.; Squire, L. R.; Eds.), Academic Press, San Diego pp. 1254-79.
34. Wise, R. A. (1998) Drug-activation of brain reward pathways. Drug Alcohol Depend 51, 13-22. (Pubitemid 28353753)
35. Wise, R. A. (1997) Drug self-administration viewed as ingestive behaviour. Appetite 28, 1-5. (Pubitemid 27192362)
36. Avena, N. M.; Rada, P.; Moise, N.; Hoebel, B. G. (2006) Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response. Neuroscience 139, 813-20.
37. Bassareo, V.; Di Chiara, G. (1997) Differential infl uence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. J Neurosci 17, 851-61. (Pubitemid 27024596)
38. Avena, N. M.; Bocarsly, M. E.; Kim, A.; Rada, P.; Hoebel, B. G. (2008) After daily bingeing on a sucrose solution, prolonged food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance. Physiol Behav 94, 309-15. (Pubitemid 351680280)
39. Rada, P.; Jensen, K.; Hoebel, B. G. (2001) Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens. Psychopharmacology (Berl) 157, 105-10. (Pubitemid 32758966)
40. Rada, P.; Johnson, D. F.; Lewis, M. J.; Hoebel, B. G. (2004) In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal. Pharmacol Biochem Behav 79, 599-605. (Pubitemid 39600600)
41. Rada, P.; Pothos, E.; Mark, G. P.; Hoebel, B. G. (1991) Microdialysis evidence that acetylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine. Brain Res 561, 354-6.
42. Rada, P. V.; Mark, G. P.; Taylor, K. M.; Hoebel, B. G. (1996) Morphine and naloxone, i.p. or locally, affect extracellular acetylcholine in the accumbens and prefrontal cortex. Pharmacol Biochem Behav 53, 809-16. (Pubitemid 26112946)
43. Avena, N. M.; Long, K. A.; Hoebel, B. G. (2005) Sugar-dependent rats show enhanced responding for sugar after abstinence: evidence of a sugar deprivation effect. Physiol Behav 84, 359-62. (Pubitemid 40342589)
44. American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision (DSMIV- TR), American Psychiatric Association, Washington, DC.
45. Corwin, R. L.; Wojnicki, F. H.; Fisher, J. O.; Dimitriou, S. G.; Rice, H. B.; Young, M. A. (1998) Limited access to a dietary fat option affects ingestive behavior but not body composition in male rats. Physiol Behav 65, 545-53. (Pubitemid 29015772)
46. Dimitriou, S. G.; Rice, H. B.; Corwin, R. L. (2000) Effects of limited access to a fat option on food intake and body composition in female rats. Int J Eat Disord 28, 436-45.
47. Boggiano, M. M.; Chandler, P. C.; Viana, J. B.; Oswald, K. D.; Maldonado, C. R.; Wauford, P. K. (2005) Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. Behav Neurosci 119, 1207-14. (Pubitemid 41598733)
48. Boggiano, M. M.; Chandler, P. C. (2006) Binge eating in rats produced by combining dieting with stress. Curr Protoc Neurosci Chapter 9, Unit9 23A.
49. Berner, L. A.; Avena, N. M.; Hoebel, B. G. (2008) Bingeing, Self-restriction, and Increased Body Weight in Rats With Limited Access to a Sweet-fat Diet. Obesity (Silver Spring) 16, 1998-2002.
50. Berner, L. A.; Bocarsly, M. E.; Hoebel, B. G.; Avena, N. M. (2009) Baclofen suppresses binge eating of pure fat but not a sugar-rich or sweet-fat diet. Behav Pharmacol 20, 631-4.
51. Allison, S.; Timmerman, G. M. (2007) Anatomy of a binge: food environment and characteristics of nonpurge binge episodes. Eat Behav 8, 31-8. (Pubitemid 44890835)
52. Guertin, T. L.; Conger, A. J. (1999) Mood and forbidden foods infl uence on perceptions of binge eating. Addict Behav 24, 175-93. (Pubitemid 29147116)
53. Hadigan, C. M.; Kissileff, H. R.; Walsh, B. T. (1989) Patterns of food selection during meals in women with bulimia. Am J Clin Nutr 50, 759-66. (Pubitemid 19252732)
54. Kales, E. F. (1990) Macronutrient analysis of binge eating in bulimia. Physiol Behav 48, 837-40.
55. Kelley, A. E.; Will, M. J.; Steininger, T. L.; Zhang, M.; Haber, S. N. (2003) Restricted daily consumption of a highly palatable food (chocolate Ensure(R)) alters striatal enkephalin gene expression. Eur J Neurosci 18, 2592-8. (Pubitemid 37455408)
56. Liang, N. C.; Hajnal, A.; Norgren, R. (2006) Sham feeding corn oil increases accumbens dopamine in the rat. Am J Physiol Regul Integr Comp Physiol 291, R1236-9.
57. Teegarden, S. L.; Bale, T. L. (2007) Decreases in dietary preference produce increased emotionality and risk for dietary relapse. Biol Psychiatry 61, 1021-9. (Pubitemid 46551977)
58. Teegarden, S. L.; Nestler, E. J.; Bale, T. L. (2008) Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biol Psychiatry 64, 941-50.
59. Johnson, P. M.; Kenny, P. J. (2010) Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nat Neurosci 13, 635-41.
60. Cottone, P.; Sabino, V.; Steardo, L.; Zorrilla, E. P. (2009) Consummatory, anxietyrelated and metabolic adaptations in female rats with alternating access to preferred food. Psychoneuroendocrinology 34, 38-49.
61. Corwin, R. L.; Buda-Levin, A. (2004) Behavioral models of binge-type eating. Physiol Behav 82, 123-30. (Pubitemid 38968518)
62. Mazda, T.; Yamamoto, H.; Fujimura, M.; Fujimiya, M. (2004) Gastric distension-induced release of 5-HT stimulates c-fos expression in specifi c brain nuclei via 5-HT3 receptors in conscious rats. Am J Physiol Gastrointest Liver Physiol 287, G228-35. (Pubitemid 38802137)
63. Avena, N. M.; Rada, P.; Hoebel, B. G. (2008) Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose. Neuroscience 156, 865-71.