A selective ALDH-2 inhibitor reduces anxiety in rats

Pharmacology Biochemistry and Behavior

Volumn 94, Issue 2, 2009, Pages 255-261

  Overstreet, David H ^a   Knapp, Darin J ^a   Breese, George R ^a   Diamond, Ivan ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b CV THERAPEUTICS INC   (United States)

Author keywords

ALDH 2 inhibitor; Anxiogenic behavior; DMCM; Ethanol withdrawal; Fawn Hooded rats; mCPP; Restraint stress; Social interaction test

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE INHIBITOR; CVT 10216; UNCLASSIFIED DRUG;

ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; IMMOBILIZATION STRESS; NONHUMAN; PRIMARY PREVENTION; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SOCIAL INTERACTION; TRANQUILIZING ACTIVITY;

ALCOHOL DETERRENTS; ALDEHYDE DEHYDROGENASE; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DOSE-RESPONSE RELATIONSHIP, DRUG; ISOFLAVONES; MITOCHONDRIAL PROTEINS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS; RODENTIA;

EID: 72049094527     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.09.004     Document Type: Article

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