Nanoparticle formulation enhanced protective immunity provoked by PYGPI8p-transamidase related protein (PyTAM) DNA vaccine in Plasmodium yoelii malaria model

Vaccine

Volumn 32, Issue 17, 2014, Pages 1998-2006

  Cherif, Mahamoud Sama ^a,c   Shuaibu, Mohammed Nasir ^a   Kodama, Yukinobu ^a   Kurosaki, Tomoaki ^a   Helegbe, Gideon Kofi ^a   Kikuchi, Mihoko ^a   Ichinose, Akitoyo ^a   Yanagi, Tetsuo ^b   Sasaki, Hitoshi ^a   Yui, Katsuyuki ^a   Tien, Nguyen Huy ^a   Karbwang, Juntra ^a   Hirayama, Kenji ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b Animal Research Center for Tropical Medicine   (Japan)

^c Université Gamal Abdel Nasser de Conakry   (Guinea)

Author keywords

DNA vaccine; Gamma polyglutamic acid ( PGA); GPI8p transamidase; Nanoparticle; Plasmodium yoelii; Polyethylimine (PEI)

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; INTERLEUKIN 12; INTERLEUKIN 4; NANOPARTICLE; PLASMID DNA; POLYGLUTAMIC ACID; PROTEIN; PROTEIN PYTAM; SIGNAL PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG FORMULATION; FEMALE; MOUSE; NONHUMAN; PARASITE IMMUNITY; PLASMODIUM YOELII INFECTION; PRIORITY JOURNAL; SPLEEN CELL; SURVIVAL RATE;

DNA VACCINE; GAMMA POLYGLUTAMIC ACID (Γ-PGA); GPI8P-TRANSAMIDASE; NANOPARTICLE; PLASMODIUM YOELII; POLYETHYLIMINE (PEI);

ANIMALS; ANTIBODIES, PROTOZOAN; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; INTERFERON-GAMMA; INTERLEUKIN-12; MALARIA; MALARIA VACCINES; MICE; MICE, INBRED C57BL; NANOPARTICLES; PLASMODIUM YOELII; POLYETHYLENEIMINE; POLYGLUTAMIC ACID; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SPLEEN; T-LYMPHOCYTES; VACCINES, DNA;

EID: 84896315325     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.01.005     Document Type: Article

References (54)

1. W.H.O. World Malaria Report 2011 2011, WHO Global Malaria Programme.
2. Tang D.C., DeVit M., Johnston S.A. Genetic immunization is a simple method for eliciting an immune response. Nature 1992, 356(March (6365)):152-154.
3. Shuaibu M.N., Kikuchi M., Cherif M.S., Helegbe G.K., Yanagi T., Hirayama K. Selection and identification of malaria vaccine target molecule using bioinformatics and DNA vaccination. Vaccine 2010, 28(October (42)):6868-6875.
4. Goel V.K., Li X., Chen H., Liu S.C., Chishti A.H., Oh S.S. Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes. Proc Natl Acad Sci U S A 2003, 100(April (9)):5164-5169.
5. Li X., Chen H., Oo T.H., Daly T.M., Bergman L.W., Liu S.C., et al. A co-ligand complex anchors Plasmodium falciparum merozoites to the erythrocyte invasion receptor band 3. J Biol Chem 2004, 279(February (7)):5765-5771.
6. Blackman M.J. Proteases involved in erythrocyte invasion by the malaria parasite: function and potential as chemotherapeutic targets. Curr Drug Targets 2000, 1(July (1)):59-83.
7. Ohishi K., Inoue N., Maeda Y., Takeda J., Riezman H., Kinoshita T. Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins. Mol Biol Cell 2000, 11(May (5)):1523-1533.
8. Spurway T.D., Dalley J.A., High S., Bulleid N.J. Early events in glycosylphosphatidylinositol anchor addition. Substrate proteins associate with the transamidase subunit gpi8p. J Biol Chem 2001, 276(May (19)):15975-15982.
9. Cherif M.S., Shuaibu M.N., Kurosaki T., Helegbe G.K., Kikuchi M., Yanagi T., et al. Immunogenicity of novel nanoparticle-coated MSP-1 C-terminus malaria DNA vaccine using different routes of administration. Vaccine 2011, 29(November (48)):9038-9050.
10. Uto T., Wang X., Sato K., Haraguchi M., Akagi T., Akashi M., et al. Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity. J Immunol 2007, 178(March (5)):2979-2986.
11. Akagi T., Wang X., Uto T., Baba M., Akashi M. Protein direct delivery to dendritic cells using nanoparticles based on amphiphilic poly(amino acid) derivatives. Biomaterials 2007, 28(August (23)):3427-3436.
12. Team TEP. The Plasmodium genome resource. PlasmoDB Versin 9.3; June 13.
13. NCfBI Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 2002, 30(1):13-16.
14. Kurosaki T., Kitahara T., Fumoto S., Nishida K., Nakamura J., Niidome T., et al. Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems. Biomaterials 2009, 30(May (14)):2846-2853.
15. Shuaibu M.N., Cherif M.S., Kurosaki T., Helegbe G.K., Kikuchi M., Yanagi T., et al. Effect of nanoparticle coating on the immunogenicity of plasmid DNA vaccine encoding P. yoelii MSP-1 C-terminal. Vaccine 2011, 29(April (17)):3239-3247.
16. Peng S.F., Tseng M.T., Ho Y.C., Wei M.C., Liao Z.X., Sung H.W. Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly(gamma-glutamic acid) complexes as a gene delivery vector. Biomaterials 2011, 32(January (1)):239-248.
17. Fahmy T.M., Demento S.L., Caplan M.J., Mellman I., Saltzman W.M. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond) 2008, 3(June (3)):343-355.
18. Ali J., Ali M., Baboota S., Sahani J.K., Ramassamy C., Dao L., et al. Potential of nanoparticulate drug delivery systems by intranasal administration. Curr Pharm Des 2010, 16(May (14)):1644-1653.
19. Demento S.L., Cui W., Criscione J.M., Stern E., Tulipan J., Kaech S.M., et al. Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype. Biomaterials 2012, 33(June (19)):4957-4964.
20. Knuschke T., Sokolova V., Rotan O., Wadwa M., Tenbusch M., Hansen W., et al. Immunization with biodegradable nanoparticles efficiently induces cellular immunity and protects against influenza virus infection. J Immunol 2013, 190(June (12)):6221-6229.
21. Parlane N.A., Rehm B.H., Wedlock D.N., Buddle B.M. Novel particulate vaccines utilizing polyester nanoparticles (bio-beads) for protection against Mycobacterium bovis infection - a review. Vet Immunol Immunopathol 2013, 122(13):165-2427.
22. Nawwab Al-Deen F., Ma C., Xiang S.D., Selomulya C., Plebanski M., Coppel R.L. On the efficacy of malaria DNA vaccination with magnetic gene vectors. J Control Release 2013, 168(May (1)):10-17.
23. Pombo D.J., Lawrence G., Hirunpetcharat C., Rzepczyk C., Bryden M., Cloonan N., et al. Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet 2002, 360(August (9333)):610-617.
24. Wipasa J., Xu H., Makobongo M., Gatton M., Stowers A., Good M.F. Nature and specificity of the required protective immune response that develops postchallenge in mice vaccinated with the 19-kilodalton fragment of Plasmodium yoelii merozoite surface protein 1. Infect Immun 2002, 70(November (11)):6013-6020.
25. Majarian W.R., Daly T.M., Weidanz W.P., Long C.A. Passive immunization against murine malaria with an IgG3 monoclonal antibody. J Immunol 1984, 132(June (6)):3131-3137.
26. Spencer Valero L.M., Ogun S.A., Fleck S.L., Ling I.T., Scott-Finnigan T.J., Blackman M.J., et al. Passive immunization with antibodies against three distinct epitopes on Plasmodium yoelii merozoite surface protein 1 suppresses parasitemia. Infect Immun 1998, 66(August (8)):3925-3930.
27. Holder A.A. The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria. Parasitology 2009, 136(October (12)):1445-1456.
28. Okoye A.A., Picker L.J. CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure. Immunol Rev 2013, 254(July (1)):54-64.
29. Ng C.T., Snell L.M., Brooks D.G., Oldstone M.B. Networking at the level of host immunity: immune cell interactions during persistent viral infections. Cell Host Microbe 2013, 13(June (6)):652-664.
30. Cordery D.V., Urban B.C. Immune recognition of Plasmodium-infected erythrocytes. Adv Exp Med Biol 2009, 653:175-184.
31. Riley E.M., Stewart V.A. Immune mechanisms in malaria: new insights in vaccine development. Nat Med 2013, 19(February (2)):168-178.
32. Wilson-Welder J.H., Torres M.P., Kipper M.J., Mallapragada S.K., Wannemuehler M.J., Narasimhan B. Vaccine adjuvants: current challenges and future approaches. J Pharm Sci 2009, 98(April (4)):1278-1316.
33. Bracci L., La Sorsa V., Belardelli F., Proietti E. Type I interferons as vaccine adjuvants against infectious diseases and cancer. Expert Rev Vaccines 2008, 7(April (3)):373-381.
34. Verfaillie T., Cox E., Goddeeris B.M. Immunostimulatory capacity of DNA vaccine vectors in porcine PBMC: a specific role for CpG-motifs?. Vet Immunol Immunopathol 2005, 103(January (1-2)):141-151.
35. Schneeberger A., Wagner C., Zemann A., Luhrs P., Kutil R., Goos M., et al. CpG motifs are efficient adjuvants for DNA cancer vaccines. J Invest Dermatol 2004, 123(August (2)):371-379.
36. Burocchi A., Pittoni P., Gorzanelli A., Colombo M.P., Piconese S. Intratumor OX40 stimulation inhibits IRF1 expression and IL-10 production by Treg cells while enhancing CD40L expression by effector memory T cells. Eur J Immunol 2011, 41(December (12)):3615-3626.
37. Hodge J.W., Greiner J.W., Tsang K.Y., Sabzevari H., Kudo-Saito C., Grosenbach D.W., et al. Costimulatory molecules as adjuvants for immunotherapy. Front Biosci 2006, 11:788-803.
38. Mann J.F., McKay P.F., Arokiasamy S., Patel R.K., Klein K., Shattock R.J. Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection. J Control Release 2013, 170(June (3)):452-459.
39. Garmory H.S., Brown K.A., Titball R.W. DNA vaccines: improving expression of antigens. Genet Vaccines Ther 2003, 1(September (1)):2.
40. Dobrovolskaia M.A., McNeil S.E. Immunological properties of engineered nanomaterials. Nat Nanotechnol 2007, 2(August (8)):469-478.
41. Zolnik B.S., Gonzalez-Fernandez A., Sadrieh N., Dobrovolskaia M.A. Nanoparticles and the immune system. Endocrinology 2010, 151(February (2)):458-465.
42. Dobrovolskaia M.A., Aggarwal P., Hall J.B., McNeil S.E. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Mol Pharm 2008, 5(July-August (4)):487-495.
43. Liao Z.X., Peng S.F., Ho Y.C., Mi F.L., Maiti B., Sung H.W. Mechanistic study of transfection of chitosan/DNA complexes coated by anionic poly(gamma-glutamic acid). Biomaterials 2012, 33(April (11)):3306-3315.
44. Guermonprez P., Valladeau J., Zitvogel L., Thery C., Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol 2002, 20:621-667.
45. Zhou L.J., Tedder T.F. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci U S A 1996, 93(March (6)):2588-2592.
46. Koch F., Stanzl U., Jennewein P., Janke K., Heufler C., Kampgen E., et al. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med 1996, 184(August (2)):741-746.
47. Lutz M.B., Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?. Trends Immunol 2002, 23(September (9)):445-449.
48. Nakano H., Yanagita M., Gunn M.D. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med 2001, 194(October (8)):1171-1178.
49. Bjorck P. Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice. Blood 2001, 98(December (13)):3520-3526.
50. Steinman R.M., Cohn Z.A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 1973, 137(May (5)):1142-1162.
51. Fahlen-Yrlid L., Gustafsson T., Westlund J., Holmberg A., Strombeck A., Blomquist M., et al. CD11c(high)dendritic cells are essential for activation of CD4+ T cells and generation of specific antibodies following mucosal immunization. J Immunol 2009, 183(October (8)):5032-5041.
52. Corinti S., Albanesi C., la Sala A., Pastore S., Girolomoni G. Regulatory activity of autocrine IL-10 on dendritic cell functions. J Immunol 2001, 166(April (7)):4312-4318.
53. Fukao T., Frucht D.M., Yap G., Gadina M., O'Shea J.J., Koyasu S. Inducible expression of Stat4 in dendritic cells and macrophages and its critical role in innate and adaptive immune responses. J Immunol 2001, 166(April (7)):4446-4455.
54. Mottram J.C., Helms M.J., Coombs G.H., Sajid M. Clan CD cysteine peptidases of parasitic protozoa. Trends Parasitol 2003, 19(April (4)):182-187.