-
1
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
Nagase H, Visse R, Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 2006;69:562-73.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
2
-
-
40349087284
-
Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: Destruction or repair?
-
Murphy G, Nagase H. Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair? Nat Clin Pract Rheum 2008;4:128-35.
-
(2008)
Nat Clin Pract Rheum
, vol.4
, pp. 128-135
-
-
Murphy, G.1
Nagase, H.2
-
3
-
-
0028158689
-
Synovial tissue macrophages and joint erosion in rheumatoid arthritis
-
Yanni G, Whelan A, Feighery C, Bresnihan B. Synovial tissue macrophages and joint erosion in rheumatoid arthritis. Ann Rheum Dis 1994;53:39-44.
-
(1994)
Ann Rheum Dis
, vol.53
, pp. 39-44
-
-
Yanni, G.1
Whelan, A.2
Feighery, C.3
Bresnihan, B.4
-
4
-
-
0027515289
-
Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages
-
Shapiro SD, Kobayashi DK, Ley TJ. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem 1993;268:23824-9.
-
(1993)
J Biol Chem
, vol.268
, pp. 23824-23829
-
-
Shapiro, S.D.1
Kobayashi, D.K.2
Ley, T.J.3
-
5
-
-
5644277560
-
Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis
-
Liu M, Sun H, Wang X, Koike T, Mishima H, Ikeda K, et al. Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis. Arthritis Rheum 2004;50:3112-7.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3112-3117
-
-
Liu, M.1
Sun, H.2
Wang, X.3
Koike, T.4
Mishima, H.5
Ikeda, K.6
-
6
-
-
4644311909
-
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits
-
Wang X, Liang J, Koike T, Sun H, Ichikawa T, Kitajima S, et al. Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits. Am J Pathol 2004;165:1375-83.
-
(2004)
Am J Pathol
, vol.165
, pp. 1375-1383
-
-
Wang, X.1
Liang, J.2
Koike, T.3
Sun, H.4
Ichikawa, T.5
Kitajima, S.6
-
7
-
-
77951586059
-
Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis
-
Jungel A, Ospelt C, Lesch M, Thiel M, Sunyer T, Schorr O, et al. Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis. Ann Rheum Dis 2010;69:898-902.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 898-902
-
-
Jungel, A.1
Ospelt, C.2
Lesch, M.3
Thiel, M.4
Sunyer, T.5
Schorr, O.6
-
8
-
-
73249137617
-
Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
-
Little CB, Barai A, Burkhardt D, Smith SM, Fosang AJ, Werb Z, et al. Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum 2009;60:3723-33.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3723-3733
-
-
Little, C.B.1
Barai, A.2
Burkhardt, D.3
Smith, S.M.4
Fosang, A.J.5
Werb, Z.6
-
9
-
-
78650437352
-
Regulation of matrix metalloproteinase activity in health and disease
-
Hadler-Olsen E, Fadnes B, Sylte I, Uhlin-Hansen L, Winberg JO. Regulation of matrix metalloproteinase activity in health and disease. FEBS J 2011;278:28-45.
-
(2011)
FEBS J
, vol.278
, pp. 28-45
-
-
Hadler-Olsen, E.1
Fadnes, B.2
Sylte, I.3
Uhlin-Hansen, L.4
Winberg, J.O.5
-
10
-
-
77149137406
-
Matrix metalloproteinases: Evolution gene regulation and functional analysis in mouse models
-
Fanjul-Fernandez M, Folgueras AR, Cabrera S, Lopez-Otin C. Matrix metalloproteinases: evolution, gene regulation and functional analysis in mouse models. Biochim Biophys Acta 2010;1803: 3-19.
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 3-19
-
-
Fanjul-Fernandez, M.1
Folgueras, A.R.2
Cabrera, S.3
Lopez-Otin, C.4
-
11
-
-
82755197933
-
Proteases involved in cartilage matrix degradation in osteoarthritis
-
Troeberg L, Nagase H. Proteases involved in cartilage matrix degradation in osteoarthritis. Biochim Biophys Acta 2012;1824: 133-45.
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 133-145
-
-
Troeberg, L.1
Nagase, H.2
-
13
-
-
83055180536
-
Functional imaging of proteases: Recent advances in the design and application of substrate-based and activity-based probes
-
Edgington LE, Verdoes M, Bogyo M. Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes. Curr Opin Chem Biol 2011;15:798-805.
-
(2011)
Curr Opin Chem Biol
, vol.15
, pp. 798-805
-
-
Edgington, L.E.1
Verdoes, M.2
Bogyo, M.3
-
14
-
-
33644825565
-
Dynamic imaging of protease activity with fluorescently quenched activity-based probes
-
Blum G, Mullins SR, Keren K, Fonovic M, Jedeszko C, Rice MJ, et al. Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nat Chem Biol 2005;1:203-9.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 203-209
-
-
Blum, G.1
Mullins, S.R.2
Keren, K.3
Fonovic, M.4
Jedeszko, C.5
Rice, M.J.6
-
15
-
-
34548666006
-
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
-
Blum G, von Degenfeld G, Merchant MJ, Blau HM, Bogyo M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol 2007;3:668-77.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 668-677
-
-
Blum, G.1
Von Degenfeld, G.2
Merchant, M.J.3
Blau, H.M.4
Bogyo, M.5
-
16
-
-
68349148319
-
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes
-
Edgington LE, Berger AB, Blum G, Albrow VE, Paulick MG, Lineberry N, et al. Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes. Nat Med 2009;15:967-73.
-
(2009)
Nat Med
, vol.15
, pp. 967-973
-
-
Edgington, L.E.1
Berger, A.B.2
Blum, G.3
Albrow, V.E.4
Paulick, M.G.5
Lineberry, N.6
-
17
-
-
0032951071
-
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
-
Weissleder R, Tung CH, Mahmood U, Bogdanov A Jr. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 1999;17:375-8.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 375-378
-
-
Weissleder, R.1
Tung, C.H.2
Mahmood, U.3
Bogdanov, Jr.A.4
-
18
-
-
34247575810
-
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor
-
Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, et al. Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor. Circulation 2007;115:2292-8.
-
(2007)
Circulation
, vol.115
, pp. 2292-2298
-
-
Jaffer, F.A.1
Kim, D.E.2
Quinti, L.3
Tung, C.H.4
Aikawa, E.5
Pande, A.N.6
-
19
-
-
79551503110
-
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
-
Caglic D, Globisch A, Kindermann M, Lim NH, Jeske V, Juretschke HP, et al. Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation. Bioorg Med Chem 2011;19:1055-61.
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 1055-1061
-
-
Caglic, D.1
Globisch, A.2
Kindermann, M.3
Lim, N.H.4
Jeske, V.5
Juretschke, H.P.6
-
20
-
-
84865152111
-
Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-α
-
Li J, Chen K, Liu H, Cheng K, Yang M, Zhang J, et al. Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-α. Bioconjug Chem 2012;23:1704-11.
-
(2012)
Bioconjug Chem
, vol.23
, pp. 1704-1711
-
-
Li, J.1
Chen, K.2
Liu, H.3
Cheng, K.4
Yang, M.5
Zhang, J.6
-
21
-
-
17144416842
-
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction
-
Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation 2005;111:1800-5.
-
(2005)
Circulation
, vol.111
, pp. 1800-1805
-
-
Chen, J.1
Tung, C.H.2
Allport, J.R.3
Chen, S.4
Weissleder, R.5
Huang, P.L.6
-
22
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
Jiang T, Olson ES, Nguyen QT, Roy M, Jennings PA, Tsien RY. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A 2004;101:17867-72.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17867-17872
-
-
Jiang, T.1
Olson, E.S.2
Nguyen, Q.T.3
Roy, M.4
Jennings, P.A.5
Tsien, R.Y.6
-
23
-
-
38049057786
-
Selective activity-based probes for cysteine cathepsins
-
Watzke A, Kosec G, Kindermann M, Jeske V, Nestler HP, Turk V, et al. Selective activity-based probes for cysteine cathepsins. Angew Chem Int Ed Engl 2008;47:406-9.
-
(2008)
Angew Chem Int Ed Engl
, vol.47
, pp. 406-409
-
-
Watzke, A.1
Kosec, G.2
Kindermann, M.3
Jeske, V.4
Nestler, H.P.5
Turk, V.6
-
24
-
-
0034323969
-
Solid phase combinatorial library of phosphinic peptides for discovery of matrix metalloproteinase inhibitors
-
Buchardt J, Schiodt CB, Krog-Jensen C, Delaisse JM, Foged NT, Meldal M. Solid phase combinatorial library of phosphinic peptides for discovery of matrix metalloproteinase inhibitors. J Comb Chem 2000;2:624-38.
-
(2000)
J Comb Chem
, vol.2
, pp. 624-638
-
-
Buchardt, J.1
Schiodt, C.B.2
Krog-Jensen, C.3
Delaisse, J.M.4
Foged, N.T.5
Meldal, M.6
-
25
-
-
0027457712
-
Multiple column peptide synthesis, part 2 (1, 2)
-
Meldal M, Holm CB, Bojesen G, Jakobsen MH, Holm A. Multiple column peptide synthesis, Part 2 (1, 2). Int J Pept Protein Res 1993;41:250-60.
-
(1993)
Int J Pept Protein Res
, vol.41
, pp. 250-260
-
-
Meldal, M.1
Holm, C.B.2
Bojesen, G.3
Jakobsen, M.H.4
Holm, A.5
-
26
-
-
2242428037
-
Coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: Insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)
-
Troeberg L, Tanaka M, Wait R, Shi YE, Brew K, Nagase H. E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A). Biochemistry 2002;41: 15025-35.
-
(2002)
Biochemistry
, vol.41
, pp. 15025-15035
-
-
Troeberg, L.1
Tanaka, M.2
Wait, R.3
Shi, Y.E.4
Brew, K.5
Nagase, H.E.6
-
27
-
-
33646804364
-
Development of selective inhibitors and substrate of matrix metalloproteinase-12
-
Devel L, Rogakos V, David A, Makaritis A, Beau F, Cuniasse P, et al. Development of selective inhibitors and substrate of matrix metalloproteinase- 12. J Biol Chem 2006;281:11152-60.
-
(2006)
J Biol Chem
, vol.281
, pp. 11152-11160
-
-
Devel, L.1
Rogakos, V.2
David, A.3
Makaritis, A.4
Beau, F.5
Cuniasse, P.6
-
28
-
-
84863331969
-
Defining the requirements for collagenase cleavage in collagen type III using a bacterial collagen system
-
Yu Z, Visse R, Inouye M, Nagase H, Brodsky B. Defining the requirements for collagenase cleavage in collagen type III using a bacterial collagen system. J Biol Chem 2012;287:22988-97.
-
(2012)
J Biol Chem
, vol.287
, pp. 22988-22997
-
-
Yu, Z.1
Visse, R.2
Inouye, M.3
Nagase, H.4
Brodsky, B.5
-
29
-
-
68549135187
-
N-O-isopropyl sulfonamido-based hydroxamates: Design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis
-
Nuti E, Casalini F, Avramova SI, Santamaria S, Cercignani G, Marinelli L, et al. N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis. J Med Chem 2009;52:4757-73.
-
(2009)
J Med Chem
, vol.52
, pp. 4757-4773
-
-
Nuti, E.1
Casalini, F.2
Avramova, S.I.3
Santamaria, S.4
Cercignani, G.5
Marinelli, L.6
-
30
-
-
42049121842
-
Protocol for the induction of arthritis in C57BL/6 mice
-
Inglis JJ, Simelyte E, McCann FE, Criado G, Williams RO. Protocol for the induction of arthritis in C57BL/6 mice. Nat Protoc 2008;3:612-8.
-
(2008)
Nat Protoc
, vol.3
, pp. 612-618
-
-
Inglis, J.J.1
Simelyte, E.2
McCann, F.E.3
Criado, G.4
Williams, R.O.5
-
31
-
-
0031847419
-
Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: Relationship to lesion development
-
Matsumoto S, Kobayashi T, Katoh M, Saito S, Ikeda Y, Kobori M, et al. Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development. Am J Pathol 1998;153:109-19.
-
(1998)
Am J Pathol
, vol.153
, pp. 109-119
-
-
Matsumoto, S.1
Kobayashi, T.2
Katoh, M.3
Saito, S.4
Ikeda, Y.5
Kobori, M.6
-
32
-
-
82455163735
-
Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic matrix metalloproteinase 3-specific polymeric probe
-
Ryu JH, Lee A, Chu JU, Koo H, Ko CY, Kim HS, et al. Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic matrix metalloproteinase 3-specific polymeric probe. Arthritis Rheum 2011;63:3824-32.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3824-3832
-
-
Ryu, J.H.1
Lee, A.2
Chu, J.U.3
Koo, H.4
Ko, C.Y.5
Kim, H.S.6
-
33
-
-
54049106148
-
+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: Potential role of the macrophage in terminating polymorphonuclear leukocyte influx
-
+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx. Blood 2008;112:3455-64.
-
(2008)
Blood
, vol.112
, pp. 3455-3464
-
-
Dean, R.A.1
Cox, J.H.2
Bellac, C.L.3
Doucet, A.4
Starr, A.E.5
Overall, C.M.6
-
34
-
-
84855272503
-
Macrophage positron emission tomography imaging as a biomarker for preclinical rheumatoid arthritis: Findings of a prospective pilot study
-
Gent YY, Voskuyl AE, Kloet RW, van Schaardenburg D, Hoekstra OS, Dijkmans BA, et al. Macrophage positron emission tomography imaging as a biomarker for preclinical rheumatoid arthritis: findings of a prospective pilot study. Arthritis Rheum 2012;64:62-6.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 62-66
-
-
Gent, Y.Y.1
Voskuyl, A.E.2
Kloet, R.W.3
Van Schaardenburg, D.4
Hoekstra, O.S.5
Dijkmans, B.A.6
-
35
-
-
70350491339
-
Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: An evaluation from 1 to 4 years after diagnosis
-
Verstappen SM, Poole AR, Ionescu M, King LE, Abrahamowicz M, Hofman DM, et al. Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: an evaluation from 1 to 4 years after diagnosis. Arthritis Res Ther 2006;8:R31.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Verstappen, S.M.1
Poole, A.R.2
Ionescu, M.3
King, L.E.4
Abrahamowicz, M.5
Hofman, D.M.6
-
36
-
-
0035165385
-
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
-
Neuhold LA, Killar L, Zhao W, Sung ML, Warner L, Kulik J, et al. Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice. J Clin Invest 2001;107:35-44.
-
(2001)
J Clin Invest
, vol.107
, pp. 35-44
-
-
Neuhold, L.A.1
Killar, L.2
Zhao, W.3
Sung, M.L.4
Warner, L.5
Kulik, J.6
-
37
-
-
54549103634
-
Gene expression profiles at different stages of collagen-induced arthritis
-
Booth G, Newham P, Barlow R, Raines S, Zheng B, Han S. Gene expression profiles at different stages of collagen-induced arthritis. Autoimmunity 2008;41:512-21.
-
(2008)
Autoimmunity
, vol.41
, pp. 512-521
-
-
Booth, G.1
Newham, P.2
Barlow, R.3
Raines, S.4
Zheng, B.5
Han, S.6
-
38
-
-
52249097640
-
Dark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivo
-
Lee S, Park K, Lee SY, Ryu JH, Park JW, Ahn HJ, et al. Dark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivo. Bioconjug Chem 2008;19: 1743-7.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1743-1747
-
-
Lee, S.1
Park, K.2
Lee, S.Y.3
Ryu, J.H.4
Park, J.W.5
Ahn, H.J.6
-
39
-
-
0037693895
-
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
-
Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 2003;92:827-39.
-
(2003)
Circ Res
, vol.92
, pp. 827-839
-
-
Visse, R.1
Nagase, H.2
-
40
-
-
36849073658
-
MMPs as therapeutic targets-still a viable option?
-
Fingleton B. MMPs as therapeutic targets-still a viable option? Semin Cell Dev Biol 2008;19:61-8. Skin Diseases
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 61-68
-
-
Fingleton, B.1
|