Defining requirements for collagenase cleavage in collagen type III using a bacterial collagen system

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22988-22997

  Yu, Zhuoxin ^a   Visse, Robert ^b   Inouye, Masayori ^a   Nagase, Hideaki ^b   Brodsky, Barbara ^c  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Tufts University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC DOMAINS; CHIMERIC SUBSTRATES; CLEAVAGE SITES; COLLAGEN PROTEINS; COLLAGEN TYPE III; COLLAGENASE; COLLAGENOLYSIS; FIBRILLAR COLLAGENS; KINETIC ANALYSIS; MATRIX METALLOPROTEINASES; MECHANISM OF ACTION; NATIVE COLLAGEN; SPECIFIC SITES; STRUCTURAL REQUIREMENTS; TRIPLE HELICAL STRUCTURES; TRIPLE HELIXES;

DEGRADATION; ENZYME ACTIVITY;

COLLAGEN;

BACTERIAL PROTEIN; COLLAGEN TYPE 3; COLLAGENASE; COLLAGENASE 3; FIBRILLAR COLLAGEN; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; PROTEINASE; RECOMBINANT PROTEIN; TRYPSIN;

AMINO ACID SEQUENCE; ARTICLE; COLLAGEN DEGRADATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; KINETICS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; COLLAGEN TYPE III; COLLAGENASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EXTRACELLULAR MATRIX PROTEINS; HEK293 CELLS; HUMANS; MATRIX METALLOPROTEINASE 13; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TRYPSIN;

BACTERIA (MICROORGANISMS);

EID: 84863331969     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.348979     Document Type: Article

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