메뉴 건너뛰기




Volumn 9, Issue 2, 2014, Pages

CB1 blockade potentiates down-regulation of lipogenic gene expression in perirenal adipose tissue in high carbohydrate diet-induced obesity

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; CANNABINOID 1 RECEPTOR; FATTY ACID SYNTHASE; LIVER X RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; STEROL REGULATORY ELEMENT BINDING PROTEIN; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

EID: 84896141301     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090016     Document Type: Article
Times cited : (16)

References (54)
  • 4
    • 84866422361 scopus 로고    scopus 로고
    • Effects of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes
    • Sasakabe T, Haimoto H, Umegaki H, Wakai K (2011) Effects of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes. Diabetes Metab Syndr Obes 4: 167-174.
    • (2011) Diabetes Metab Syndr Obes , vol.4 , pp. 167-174
    • Sasakabe, T.1    Haimoto, H.2    Umegaki, H.3    Wakai, K.4
  • 5
    • 77952863834 scopus 로고    scopus 로고
    • Genetic control of de novo lipogenesis: Role in diet-induced obesity
    • Strable M S, Ntambi JM (2010) Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol 45: 199-214.
    • (2010) Crit Rev Biochem Mol Biol , vol.45 , pp. 199-214
    • Strable, M.S.1    Ntambi, J.M.2
  • 6
    • 33847006599 scopus 로고    scopus 로고
    • The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR
    • Cha JY, Repa JJ (2007) The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem 282: 743-751.
    • (2007) J Biol Chem , vol.282 , pp. 743-751
    • Cha, J.Y.1    Repa, J.J.2
  • 7
    • 58149277452 scopus 로고    scopus 로고
    • Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease
    • Morgan K, Uyuni A, Nandgiri G, Mao L, Castaneda L, et al. (2008) Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease. Eur J Gastroenterol Hepatol 20: 843-854.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 843-854
    • Morgan, K.1    Uyuni, A.2    Nandgiri, G.3    Mao, L.4    Castaneda, L.5
  • 8
    • 6344226251 scopus 로고    scopus 로고
    • Effect of carbohydrate overfeeding on whole body macronutrient metabolism and expression of lipogenic enzymes in adipose tissue of lean and overweight humans
    • DOI 10.1038/sj.ijo.0802760
    • Minehira K, Vega N, Vidal H, Acheson K, Tappy L (2004) Effect of carbohydrate overfeeding on whole body macronutrient metabolism and expression of lipogenic enzymes in adipose tissue of lean and overweight humans. Int J Obes Relat Metab Disord 28: 1291-1298. (Pubitemid 39389587)
    • (2004) International Journal of Obesity , vol.28 , Issue.10 , pp. 1291-1298
    • Minehira, K.1    Vega, N.2    Vidal, H.3    Acheson, K.4    Tappy, L.5
  • 10
    • 73949146174 scopus 로고    scopus 로고
    • The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects
    • Ortega FJ, Mayas D, Moreno-Navarrete JM, Catalan V, Gomez-Ambrosi J, et al. (2009) The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects. Obesity (Silver Spring) 18: 13-20.
    • (2009) Obesity (Silver Spring) , vol.18 , pp. 13-20
    • Ortega, F.J.1    Mayas, D.2    Moreno-Navarrete, J.M.3    Catalan, V.4    Gomez-Ambrosi, J.5
  • 12
    • 42449097191 scopus 로고    scopus 로고
    • Endocannabinoids, adipose tissue and lipid metabolism
    • DOI 10.1111/j.1365-2826.2008.01690.x
    • Pagano C, Rossato M, Vettor R (2008) Endocannabinoids, adipose tissue and lipid metabolism. J Neuroendocrinol 20 Suppl 1, 124-129. (Pubitemid 351559285)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.SUPPL. 1 , pp. 124-129
    • Pagano, C.1    Rossato, M.2    Vettor, R.3
  • 14
    • 2942683422 scopus 로고    scopus 로고
    • Abdominal obesity and dyslipidemia in the metabolic syndrome: Importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk
    • DOI 10.1210/jc.2004-0432
    • Carr MC, Brunzell JD (2004) Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. J Clin Endocrinol Metab 89: 2601-2607. (Pubitemid 38766338)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.6 , pp. 2601-2607
    • Carr, M.C.1    Brunzell, J.D.2
  • 15
    • 14644427135 scopus 로고    scopus 로고
    • Contribution of abdominal visceral obesity and insulin resistance to the cardiovascular risk profile of postmenopausal women
    • DOI 10.2337/diabetes.54.3.770
    • Piche ME, Weisnagel SJ, Corneau L, Nadeau A, Bergeron J, Lemieux S (2005) Contribution of abdominal visceral obesity and insulin resistance to the cardiovascular risk profile of postmenopausal women. Diabetes 54: 770-777. (Pubitemid 40322081)
    • (2005) Diabetes , vol.54 , Issue.3 , pp. 770-777
    • Piche, M.-E.1    Weisnagel, S.J.2    Corneau, L.3    Nadeau, A.4    Bergeron, J.5    Lemieux, S.6
  • 16
    • 79951473153 scopus 로고    scopus 로고
    • Perivascular adipose tissue and vascular disease
    • Britton KA, Fox CS (2011) Perivascular adipose tissue and vascular disease. Clin Lipidol 6: 79-91.
    • (2011) Clin Lipidol , vol.6 , pp. 79-91
    • Britton, K.A.1    Fox, C.S.2
  • 18
    • 32444440208 scopus 로고    scopus 로고
    • The emerging role of the endocannabinoid system in endocrine regulation and energy balance
    • DOI 10.1210/er.2005-0009
    • Pagotto U, Marsicano G, Cota D, Lutz B, Pasquali R (2006) The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 27: 73-100. (Pubitemid 43228239)
    • (2006) Endocrine Reviews , vol.27 , Issue.1 , pp. 73-100
    • Pagotto, U.1    Marsicano, G.2    Cota, D.3    Lutz, B.4    Pasquali, R.5
  • 20
    • 0032936642 scopus 로고    scopus 로고
    • Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
    • DOI 10.1007/s002130050953
    • Williams CM, Kirkham TC (1999) Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 143: 315-317. (Pubitemid 29204987)
    • (1999) Psychopharmacology , vol.143 , Issue.3 , pp. 315-317
    • Williams, C.M.1    Kirkham, T.C.2
  • 21
    • 26044461277 scopus 로고    scopus 로고
    • Endocannabinoids in the regulation of appetite and body weight
    • Kirkham TC (2005) Endocannabinoids in the regulation of appetite and body weight. Behav Pharmacol 16: 297-313.
    • (2005) Behav Pharmacol , vol.16 , pp. 297-313
    • Kirkham, T.C.1
  • 23
    • 79551469144 scopus 로고    scopus 로고
    • Expression of the cannabinoid system in muscle: Effects of a high-fat diet and CB1 receptor blockade
    • Crespillo A, Suárez J, Bermudez-Silva FJ, Rivera P, Vida M, et al. (2010) Expression of the cannabinoid system in muscle: effects of a high-fat diet and CB1 receptor blockade. Biochem J 433: 175-185.
    • (2010) Biochem J , vol.433 , pp. 175-185
    • Crespillo, A.1    Suárez, J.2    Bermudez-Silva, F.J.3    Rivera, P.4    Vida, M.5
  • 25
    • 51349153318 scopus 로고    scopus 로고
    • Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
    • Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, et al. (2008) Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 118: 3160-3169.
    • (2008) J Clin Invest , vol.118 , pp. 3160-3169
    • Osei-Hyiaman, D.1    Liu, J.2    Zhou, L.3    Godlewski, G.4    Harvey-White, J.5
  • 26
    • 33645532673 scopus 로고    scopus 로고
    • The role of the endocannabinoid system in the control of energy homeostasis
    • Lond
    • Osei-Hyiaman D, Harvey-White J, Batkai S, Kunos G (2006) The role of the endocannabinoid system in the control of energy homeostasis. Int J Obes (Lond) 30 Suppl 1, S33-38.
    • (2006) Int J Obes , vol.30 , Issue.SUPPL. 1
    • Osei-Hyiaman, D.1    Harvey-White, J.2    Batkai, S.3    Kunos, G.4
  • 27
    • 80054789655 scopus 로고    scopus 로고
    • Rimonabant, a cannabinoid receptor type 1 inverse agonist, inhibits hepatocyte lipogenesis by activating liver kinase B1 and AMP-activated protein kinase axis downstream of Galpha i/o inhibition
    • Wu HM, Yang YM, Kim SG (2011) Rimonabant, a cannabinoid receptor type 1 inverse agonist, inhibits hepatocyte lipogenesis by activating liver kinase B1 and AMP-activated protein kinase axis downstream of Galpha i/o inhibition. Mol Pharmacol 80: 859-869.
    • (2011) Mol Pharmacol , vol.80 , pp. 859-869
    • Wu, H.M.1    Yang, Y.M.2    Kim, S.G.3
  • 29
    • 33645796477 scopus 로고    scopus 로고
    • Cannabinoid receptor signaling
    • Howlett AC (2005) Cannabinoid receptor signaling. Handb Exp Pharmacol, (168): 53-79.
    • (2005) Handb Exp Pharmacol , Issue.168 , pp. 53-79
    • Howlett, A.C.1
  • 31
    • 79960131362 scopus 로고    scopus 로고
    • Mechanism of AMPK suppression of LXRdependent Srebp-1c transcription
    • Yap F, Craddock L, Yang J (2011) Mechanism of AMPK suppression of LXRdependent Srebp-1c transcription. Int J Biol Sci 7: 645-650.
    • (2011) Int J Biol Sci , vol.7 , pp. 645-650
    • Yap, F.1    Craddock, L.2    Yang, J.3
  • 32
    • 68949091995 scopus 로고    scopus 로고
    • Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones
    • Hwahng SH, Ki SH, Bae EJ, Kim HE, Kim SG (2009) Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones. Hepatology 49: 1913-1925.
    • (2009) Hepatology , vol.49 , pp. 1913-1925
    • Hwahng, S.H.1    Ki, S.H.2    Bae, E.J.3    Kim, H.E.4    Kim, S.G.5
  • 33
    • 0037098291 scopus 로고    scopus 로고
    • Carbohydrate responsive element-binding protein (ChREBP): A key regulator of glucose metabolism and fat storage
    • DOI 10.1016/S0006-2952(02)01012-2, PII S0006295202010122
    • Uyeda K, Yamashita H, Kawaguchi T (2002) Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage. Biochem Pharmacol 63: 2075-2080. (Pubitemid 34756672)
    • (2002) Biochemical Pharmacology , vol.63 , Issue.12 , pp. 2075-2080
    • Uyeda, K.1    Yamashita, H.2    Kawaguchi, T.3
  • 36
    • 14544298335 scopus 로고    scopus 로고
    • The role of MAPKs in adipocyte differentiation and obesity
    • DOI 10.1016/j.biochi.2004.10.018
    • Bost F, Aouadi M, Caron L, Binetruy B (2005) The role of MAPKs in adipocyte differentiation and obesity. Biochimie 87: 51-56. (Pubitemid 40298765)
    • (2005) Biochimie , vol.87 , Issue.1 SPEC. ISS. , pp. 51-56
    • Bost, F.1    Aouadi, M.2    Caron, L.3    Binetruy, B.4
  • 37
    • 84857548618 scopus 로고    scopus 로고
    • Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity
    • Kotzka J, Knebel B, Haas J, Kremer L, Jacob S, et al. (2012) Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity. PLoS One 7, e32609.
    • (2012) PLoS One , vol.7
    • Kotzka, J.1    Knebel, B.2    Haas, J.3    Kremer, L.4    Jacob, S.5
  • 39
    • 27644482283 scopus 로고    scopus 로고
    • Comprehensive algorithm for quantitative real-time polymerase chain reaction
    • DOI 10.1089/cmb.2005.12.1047
    • Zhao S, Fernald RD (2005) Comprehensive algorithm for quantitative real-time polymerase chain reaction. J Comput Biol 12: 1047-1064. (Pubitemid 41580022)
    • (2005) Journal of Computational Biology , vol.12 , Issue.8 , pp. 1047-1064
    • Zhao, S.1    Fernald, R.D.2
  • 40
    • 45449087921 scopus 로고    scopus 로고
    • qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
    • Hellemans J, Mortier G, De Paepe A, Speleman F, Vandesompele J (2007) qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol 8. R19.
    • (2007) Genome Biol , vol.8
    • Hellemans, J.1    Mortier, G.2    De Paepe, A.3    Speleman, F.4    Vandesompele, J.5
  • 41
    • 4644307556 scopus 로고    scopus 로고
    • 1 receptor antagonist, AM 251, causes a sustained reduction of daily food intake in the rat
    • DOI 10.1016/j.physbeh.2004.07.004, PII S0031938404003026
    • Chambers AP, Sharkey KA, Koopmans HS (2004) Cannabinoid (CB)1 receptor antagonist, AM 251, causes a sustained reduction of daily food intake in the rat. Physiol Behav 82: 863-869. (Pubitemid 39297082)
    • (2004) Physiology and Behavior , vol.82 , Issue.5 , pp. 863-869
    • Chambers, A.P.1    Sharkey, K.A.2    Koopmans, H.S.3
  • 44
    • 42249099620 scopus 로고    scopus 로고
    • Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets
    • Matias I, Petrosino S, Racioppi A, Capasso R, Izzo AA, et al. (2008) Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets. Mol Cell Endocrinol 286: S66-78.
    • (2008) Mol Cell Endocrinol , vol.286
    • Matias, I.1    Petrosino, S.2    Racioppi, A.3    Capasso, R.4    Izzo, A.A.5
  • 45
    • 40149084635 scopus 로고    scopus 로고
    • Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet
    • DOI 10.1038/oby.2007.106, PII OBY2007106
    • Starowicz KM, Cristino L, Matias I, Capasso R, Racioppi A, et al. (2008) Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. Obesity (Silver Spring) 16: 553-565. (Pubitemid 351328005)
    • (2008) Obesity , vol.16 , Issue.3 , pp. 553-565
    • Starowicz, K.M.1    Cristino, L.2    Matias, I.3    Capasso, R.4    Racioppi, A.5    Izzo, A.A.6    Di, M.V.7
  • 46
    • 77951595914 scopus 로고    scopus 로고
    • Peripheral metabolic effects of endocannabinoids and cannabinoid receptor blockade
    • Engeli S (2008) Peripheral metabolic effects of endocannabinoids and cannabinoid receptor blockade. Obes Facts 1: 8-15.
    • (2008) Obes Facts , vol.1 , pp. 8-15
    • Engeli, S.1
  • 48
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • DOI 10.1172/JCI27883
    • Zelcer N, Tontonoz P (2006) Liver X Receptors as integrators of metabolic and inflammatory signaling. The J. Clin Invest 116: 607-614. (Pubitemid 43326865)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 49
    • 33750602672 scopus 로고    scopus 로고
    • Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice
    • Yu R, Kim CS, Kwon BS, Kawada T (2006) Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice. Obesity 14: 1353-1362. (Pubitemid 46219660)
    • (2006) Obesity , vol.14 , Issue.8 , pp. 1353-1362
    • Yu, R.1    Kim, C.-S.2    Kwon, B.-S.3    Kawada, T.4
  • 53
    • 0034721772 scopus 로고    scopus 로고
    • MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro
    • Roth G, Kotzka J, Kremer L, Lehr S, Lohaus C, et al. (2000) MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro. J Biol Chem 275: 33302-33307.
    • (2000) J Biol Chem , vol.275 , pp. 33302-33307
    • Roth, G.1    Kotzka, J.2    Kremer, L.3    Lehr, S.4    Lohaus, C.5
  • 54
    • 0035976955 scopus 로고    scopus 로고
    • Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway
    • Greenberg AS, Shen WJ, Muliro K, Patel S, Souza SC, et al. (2001) Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway. J Biol Chem 276: 45456-45461.
    • (2001) J Biol Chem , vol.276 , pp. 45456-45461
    • Greenberg, A.S.1    Shen, W.J.2    Muliro, K.3    Patel, S.4    Souza, S.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.