메뉴 건너뛰기




Volumn 56, Issue 3, 2014, Pages 283-294

Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction

Author keywords

antenatal; brain injury; clinical trial; fetal growth restriction; intrauterine growth restriction; melatonin; sheep

Indexed keywords

MELATONIN; ANTIOXIDANT; NEUROPROTECTIVE AGENT;

EID: 84896140675     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12121     Document Type: Article
Times cited : (136)

References (54)
  • 1
    • 0041834759 scopus 로고    scopus 로고
    • Placental insufficiency and its consequences
    • Gagnon R,. Placental insufficiency and its consequences. Eur J Obstet Gynecol Reprod Biol 2003; 110: S99-S107.
    • (2003) Eur J Obstet Gynecol Reprod Biol , vol.110
    • Gagnon, R.1
  • 2
    • 16344390201 scopus 로고    scopus 로고
    • Neurodevelopmental consequences of being born SGA
    • van Wassenaer A,. Neurodevelopmental consequences of being born SGA. Pediatr Endocrinol Rev 2005; 2: 372-377.
    • (2005) Pediatr Endocrinol Rev , vol.2 , pp. 372-377
    • Van Wassenaer, A.1
  • 3
    • 3042545896 scopus 로고    scopus 로고
    • Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction
    • Tolsa CB, Zimine S, Warfield SK, et al. Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction. Pediatr Res 2004; 56: 132-138.
    • (2004) Pediatr Res , vol.56 , pp. 132-138
    • Tolsa, C.B.1    Zimine, S.2    Warfield, S.K.3
  • 4
    • 80255133403 scopus 로고    scopus 로고
    • Cerebral maturation in IUGR and appropriate for gestational age preterm babies
    • Ramenghi LA, Martinelli A, de Carli A, et al. Cerebral maturation in IUGR and appropriate for gestational age preterm babies. Reprod Sci 2011; 18: 469-475.
    • (2011) Reprod Sci , vol.18 , pp. 469-475
    • Ramenghi, L.A.1    Martinelli, A.2    De Carli, A.3
  • 5
    • 34250804225 scopus 로고    scopus 로고
    • Severe cell reduction in the future brain cortex in human growth-restricted fetuses and infants
    • :. e1-7
    • Samuelsen GB, Pakkenberg B, Bogdanovic N, et al. Severe cell reduction in the future brain cortex in human growth-restricted fetuses and infants. Am J Obstet Gynecol 2007; 197: 56. e1-7
    • (2007) Am J Obstet Gynecol , vol.197 , pp. 56
    • Samuelsen, G.B.1    Pakkenberg, B.2    Bogdanovic, N.3
  • 6
    • 84870606097 scopus 로고    scopus 로고
    • Being born small for gestational age reduces white matter integrity in adulthood: A prospective cohort study
    • Eikenes L, Martinussen MP, Lund LK, et al. Being born small for gestational age reduces white matter integrity in adulthood: a prospective cohort study. Pediatr Res 2012; 72: 649-654.
    • (2012) Pediatr Res , vol.72 , pp. 649-654
    • Eikenes, L.1    Martinussen, M.P.2    Lund, L.K.3
  • 7
    • 84864886698 scopus 로고    scopus 로고
    • Antioxidant therapies: A potential role in perinatal medicine
    • Miller SL, Wallace EM, Walker DW,. Antioxidant therapies: a potential role in perinatal medicine. Neuroendocrinology 2012; 96: 13-23.
    • (2012) Neuroendocrinology , vol.96 , pp. 13-23
    • Miller, S.L.1    Wallace, E.M.2    Walker, D.W.3
  • 8
    • 67650110707 scopus 로고    scopus 로고
    • Oxidative stress in small-for-gestational age (SGA) term newborns and their mothers
    • Gveric-Ahmetasevic S, Sunjic SB, Skala H, et al. Oxidative stress in small-for-gestational age (SGA) term newborns and their mothers. Free Radic Res 2009; 43: 376-384.
    • (2009) Free Radic Res , vol.43 , pp. 376-384
    • Gveric-Ahmetasevic, S.1    Sunjic, S.B.2    Skala, H.3
  • 9
    • 33847035592 scopus 로고    scopus 로고
    • The effects of maternal betamethasone administration on the intrauterine growth-restricted fetus
    • Miller SL, Chai M, Loose J, et al. The effects of maternal betamethasone administration on the intrauterine growth-restricted fetus. Endocrinology 2007; 148: 1288-1295.
    • (2007) Endocrinology , vol.148 , pp. 1288-1295
    • Miller, S.L.1    Chai, M.2    Loose, J.3
  • 10
    • 76749110706 scopus 로고    scopus 로고
    • Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta
    • Myatt L,. Review: reactive oxygen and nitrogen species and functional adaptation of the placenta. Placenta 2011; 31 (Suppl): S66-S69.
    • (2011) Placenta , vol.31 , Issue.SUPPL.
    • Myatt, L.1
  • 11
    • 84856244012 scopus 로고    scopus 로고
    • Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia
    • Kilic U, Yilmaz B, Ugur M, et al. Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia. J Pineal Res 2012; 52: 228-235.
    • (2012) J Pineal Res , vol.52 , pp. 228-235
    • Kilic, U.1    Yilmaz, B.2    Ugur, M.3
  • 12
    • 0027210003 scopus 로고
    • The melatonin rhythm: Both a clock and a calendar
    • Reiter RJ,. The melatonin rhythm: both a clock and a calendar. Experientia 1993; 49: 654-664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • Reiter, R.J.1
  • 13
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • Galano A, Tan DX, Reiter RJ,. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011; 51: 1-16.
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 14
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • Rodriguez C, Mayo JC, Sainz RM, et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36: 1-9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 15
    • 84874949228 scopus 로고    scopus 로고
    • On the free radical scavenging activities of melatonin's metabolites. AFMK and AMK
    • Galano A, Tan DX, Reiter RJ,. On the free radical scavenging activities of melatonin's metabolites. AFMK and AMK. J Pineal Res 2013; 54: 245-257.
    • (2013) J Pineal Res , vol.54 , pp. 245-257
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 16
    • 33846463411 scopus 로고    scopus 로고
    • Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion
    • Welin AK, Svedin P, Lapatto R, et al. Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion. Pediatr Res 2007; 61: 153-158.
    • (2007) Pediatr Res , vol.61 , pp. 153-158
    • Welin, A.K.1    Svedin, P.2    Lapatto, R.3
  • 17
    • 23244440004 scopus 로고    scopus 로고
    • Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion
    • Miller SL, Yan EB, Castillo-Melendez M, et al. Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion. Dev Neurosci 2005; 27: 200-210.
    • (2005) Dev Neurosci , vol.27 , pp. 200-210
    • Miller, S.L.1    Yan, E.B.2    Castillo-Melendez, M.3
  • 18
    • 0029788185 scopus 로고    scopus 로고
    • Melatonin effects on behavior: Possible mediation by the central GABAergic system
    • Golombek DA, Pevet P, Cardinali DP,. Melatonin effects on behavior: possible mediation by the central GABAergic system. Neurosci Biobehav Rev 1996; 20: 403-412.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 403-412
    • Golombek, D.A.1    Pevet, P.2    Cardinali, D.P.3
  • 19
    • 84892419043 scopus 로고    scopus 로고
    • Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure
    • Castillo-Melendez M, Baburamani AA, Cabalag C, et al. Experimental modelling of the consequences of brief late gestation asphyxia on newborn lamb behaviour and brain structure. PLoS ONE 2013; 8: e77377.
    • (2013) PLoS ONE , vol.8
    • Castillo-Melendez, M.1    Baburamani, A.A.2    Cabalag, C.3
  • 20
    • 0031933376 scopus 로고    scopus 로고
    • Effects of chronic placental insufficiency on brain development in fetal sheep
    • Mallard EC, Rees S, Stringer M, et al. Effects of chronic placental insufficiency on brain development in fetal sheep. Pediatr Res 1998; 43: 262-270.
    • (1998) Pediatr Res , vol.43 , pp. 262-270
    • Mallard, E.C.1    Rees, S.2    Stringer, M.3
  • 21
    • 31544474067 scopus 로고    scopus 로고
    • Chronic endotoxin exposure causes brain injury in the ovine fetus in the absence of hypoxemia
    • Duncan JR, Cock ML, Suzuki K, et al. Chronic endotoxin exposure causes brain injury in the ovine fetus in the absence of hypoxemia. J Soc Gynecol Investig 2006; 13: 87-96.
    • (2006) J Soc Gynecol Investig , vol.13 , pp. 87-96
    • Duncan, J.R.1    Cock, M.L.2    Suzuki, K.3
  • 22
    • 47149104656 scopus 로고    scopus 로고
    • Partial neuroprotection with low-dose infusion of the alpha2-adrenergic receptor agonist clonidine after severe hypoxia in preterm fetal sheep
    • Dean JM, George S, Naylor AS, et al. Partial neuroprotection with low-dose infusion of the alpha2-adrenergic receptor agonist clonidine after severe hypoxia in preterm fetal sheep. Neuropharmacology 2008; 55: 166-174.
    • (2008) Neuropharmacology , vol.55 , pp. 166-174
    • Dean, J.M.1    George, S.2    Naylor, A.S.3
  • 23
    • 35848934112 scopus 로고    scopus 로고
    • Quantification of renal pathology by image analysis
    • Rangan GK, Tesch GH,. Quantification of renal pathology by image analysis. Nephrology (Carlton) 2007; 12: 553-558.
    • (2007) Nephrology (Carlton) , vol.12 , pp. 553-558
    • Rangan, G.K.1    Tesch, G.H.2
  • 24
    • 84892595288 scopus 로고    scopus 로고
    • Antenatal melatonin as an antioxidant in human pregnancies complicated by fetal growth restriction-a phase i pilot clinical trial: Study protocol
    • Alers NO, Jenkin G, Miller SL, et al. Antenatal melatonin as an antioxidant in human pregnancies complicated by fetal growth restriction-a phase I pilot clinical trial: study protocol. BMJ Open 2013; 3: e004141.
    • (2013) BMJ Open , vol.3
    • Alers, N.O.1    Jenkin, G.2    Miller, S.L.3
  • 25
    • 0032049505 scopus 로고    scopus 로고
    • A reliable procedure for comparison of antioxidants in rat brain homogenates
    • Callaway JK, Beart PM, Jarrott B,. A reliable procedure for comparison of antioxidants in rat brain homogenates. J Pharmacol Toxicol Methods 1998; 39: 155-162.
    • (1998) J Pharmacol Toxicol Methods , vol.39 , pp. 155-162
    • Callaway, J.K.1    Beart, P.M.2    Jarrott, B.3
  • 26
    • 33644797293 scopus 로고    scopus 로고
    • Chronic fetal hypoxia increases activin A concentrations in the late-pregnant sheep
    • Supramaniam VG, Jenkin G, Loose J, et al. Chronic fetal hypoxia increases activin A concentrations in the late-pregnant sheep. BJOG 2006; 113: 102-109.
    • (2006) BJOG , vol.113 , pp. 102-109
    • Supramaniam, V.G.1    Jenkin, G.2    Loose, J.3
  • 27
    • 33745700290 scopus 로고    scopus 로고
    • Perinatal white matter injury: The changing spectrum of pathology and emerging insights into pathogenetic mechanisms
    • Back SA,. Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms. Ment Retard Dev Disabil Res Rev 2006; 12: 129-140.
    • (2006) Ment Retard Dev Disabil Res Rev , vol.12 , pp. 129-140
    • Back, S.A.1
  • 28
    • 0035066639 scopus 로고    scopus 로고
    • Biology of oligodendrocyte and myelin in the mammalian central nervous system
    • Baumann N, Pham-Dinh D,. Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev 2001; 81: 871-927.
    • (2001) Physiol Rev , vol.81 , pp. 871-927
    • Baumann, N.1    Pham-Dinh, D.2
  • 29
    • 33748076104 scopus 로고    scopus 로고
    • Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury
    • Back SA, Riddle A, Hohimer AR,. Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury. J Child Neurol 2006; 21: 582-589.
    • (2006) J Child Neurol , vol.21 , pp. 582-589
    • Back, S.A.1    Riddle, A.2    Hohimer, A.R.3
  • 30
    • 18744397557 scopus 로고    scopus 로고
    • Brain damage and axonal injury in a Scottish cohort of neonatal deaths
    • Bell JE, Becher JC, Wyatt B, et al. Brain damage and axonal injury in a Scottish cohort of neonatal deaths. Brain 2005; 128: 1070-1081.
    • (2005) Brain , vol.128 , pp. 1070-1081
    • Bell, J.E.1    Becher, J.C.2    Wyatt, B.3
  • 31
    • 70349621787 scopus 로고    scopus 로고
    • Melatonin promotes oligodendroglial maturation of injured white matter in neonatal rats
    • Olivier P, Fontaine RH, Loron G, et al. Melatonin promotes oligodendroglial maturation of injured white matter in neonatal rats. PLoS ONE 2009; 4: e7128.
    • (2009) PLoS ONE , vol.4
    • Olivier, P.1    Fontaine, R.H.2    Loron, G.3
  • 32
    • 84874006827 scopus 로고    scopus 로고
    • Mechanisms of melatonin induced protection in the brain of late gestation fetal sheep in response to hypoxia
    • Yawno T, Castillo-Melendez M, Jenkin G, et al. Mechanisms of melatonin induced protection in the brain of late gestation fetal sheep in response to hypoxia. Dev Neurosci 2012; 34: 543-551.
    • (2012) Dev Neurosci , vol.34 , pp. 543-551
    • Yawno, T.1    Castillo-Melendez, M.2    Jenkin, G.3
  • 33
    • 0023256330 scopus 로고
    • Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses
    • Soothill PW, Nicolaides KH, Campbell S,. Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses. Br Med J (Clin Res Ed) 1987; 294: 1051-1053.
    • (1987) Br Med J (Clin Res Ed) , vol.294 , pp. 1051-1053
    • Soothill, P.W.1    Nicolaides, K.H.2    Campbell, S.3
  • 34
    • 33748439141 scopus 로고    scopus 로고
    • Cerebral palsy in a term population: Risk factors and neuroimaging findings
    • Wu YW, Croen LA, Shah SJ, et al. Cerebral palsy in a term population: risk factors and neuroimaging findings. Pediatrics 2006; 118: 690-697.
    • (2006) Pediatrics , vol.118 , pp. 690-697
    • Wu, Y.W.1    Croen, L.A.2    Shah, S.J.3
  • 35
    • 38349187945 scopus 로고    scopus 로고
    • A systematic review of neuroimaging for cerebral palsy
    • Korzeniewski SJ, Birbeck G, Delano MC, et al. A systematic review of neuroimaging for cerebral palsy. J Child Neurol 2008; 23: 216-227.
    • (2008) J Child Neurol , vol.23 , pp. 216-227
    • Korzeniewski, S.J.1    Birbeck, G.2    Delano, M.C.3
  • 36
    • 84856753704 scopus 로고    scopus 로고
    • Neonatal neurobehavior and diffusion MRI changes in brain reorganization due to intrauterine growth restriction in a rabbit model
    • Eixarch E, Batalle D, Illa M, et al. Neonatal neurobehavior and diffusion MRI changes in brain reorganization due to intrauterine growth restriction in a rabbit model. PLoS ONE 2012; 7: e31497.
    • (2012) PLoS ONE , vol.7
    • Eixarch, E.1    Batalle, D.2    Illa, M.3
  • 37
    • 79952535410 scopus 로고    scopus 로고
    • Differential effects of intrauterine growth restriction on brain structure and development in preterm infants: A magnetic resonance imaging study
    • Padilla N, Falcon C, Sanz-Cortes M, et al. Differential effects of intrauterine growth restriction on brain structure and development in preterm infants: a magnetic resonance imaging study. Brain Res 2011; 1382: 98-108.
    • (2011) Brain Res , vol.1382 , pp. 98-108
    • Padilla, N.1    Falcon, C.2    Sanz-Cortes, M.3
  • 38
    • 80052556491 scopus 로고    scopus 로고
    • Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury
    • Riddle A, Dean J, Buser JR, et al. Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury. Ann Neurol 2011; 70: 493-507.
    • (2011) Ann Neurol , vol.70 , pp. 493-507
    • Riddle, A.1    Dean, J.2    Buser, J.R.3
  • 39
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H,. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991; 11: 81-128.
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 40
    • 0344069780 scopus 로고    scopus 로고
    • Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats
    • Jahnke G, Marr M, Myers C, et al. Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats. Toxicol Sci 1999; 50: 271-279.
    • (1999) Toxicol Sci , vol.50 , pp. 271-279
    • Jahnke, G.1    Marr, M.2    Myers, C.3
  • 41
    • 0030040310 scopus 로고    scopus 로고
    • E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures
    • Montine TJ, Amarnath V, Martin ME, et al. E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. Am J Pathol 1996; 148: 89-93.
    • (1996) Am J Pathol , vol.148 , pp. 89-93
    • Montine, T.J.1    Amarnath, V.2    Martin, M.E.3
  • 42
    • 0033756824 scopus 로고    scopus 로고
    • The lipid peroxidation by-product 4-hydroxynonenal is toxic to axons and oligodendrocytes
    • McCracken E, Valeriani V, Simpson C, et al. The lipid peroxidation by-product 4-hydroxynonenal is toxic to axons and oligodendrocytes. J Cereb Blood Flow Metab 2000; 20: 1529-1536.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1529-1536
    • McCracken, E.1    Valeriani, V.2    Simpson, C.3
  • 43
    • 0033006380 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin
    • Neely MD, Sidell KR, Graham DG, et al. The lipid peroxidation product 4-hydroxynonenal inhibits neurite outgrowth, disrupts neuronal microtubules, and modifies cellular tubulin. J Neurochem 1999; 72: 2323-2333.
    • (1999) J Neurochem , vol.72 , pp. 2323-2333
    • Neely, M.D.1    Sidell, K.R.2    Graham, D.G.3
  • 45
    • 33645009182 scopus 로고    scopus 로고
    • Spatial heterogeneity in oligodendrocyte lineage maturation and not cerebral blood flow predicts fetal ovine periventricular white matter injury
    • Riddle A, Luo NL, Manese M, et al. Spatial heterogeneity in oligodendrocyte lineage maturation and not cerebral blood flow predicts fetal ovine periventricular white matter injury. J Neurosci 2006; 26: 3045-3055.
    • (2006) J Neurosci , vol.26 , pp. 3045-3055
    • Riddle, A.1    Luo, N.L.2    Manese, M.3
  • 46
    • 80053932633 scopus 로고    scopus 로고
    • Intrauterine growth restriction affects the maturation of myelin
    • Tolcos M, Bateman E, O'dowd R, et al. Intrauterine growth restriction affects the maturation of myelin. Exp Neurol 2011; 232: 53-65.
    • (2011) Exp Neurol , vol.232 , pp. 53-65
    • Tolcos, M.1    Bateman, E.2    O'Dowd, R.3
  • 47
    • 41149096700 scopus 로고    scopus 로고
    • Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia
    • Billiards SS, Haynes RL, Folkerth RD, et al. Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia. Brain Pathol 2008; 18: 153-163.
    • (2008) Brain Pathol , vol.18 , pp. 153-163
    • Billiards, S.S.1    Haynes, R.L.2    Folkerth, R.D.3
  • 48
    • 69249249242 scopus 로고    scopus 로고
    • Fetal hypoxia insults and patterns of brain injury: Insights from animal models
    • Gunn AJ, Bennet L,. Fetal hypoxia insults and patterns of brain injury: insights from animal models. Clin Perinatol 2009; 36: 579-593.
    • (2009) Clin Perinatol , vol.36 , pp. 579-593
    • Gunn, A.J.1    Bennet, L.2
  • 49
    • 0028204030 scopus 로고
    • Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation
    • Mallard EC, Williams CE, Johnston BM, et al. Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation. Am J Obstet Gynecol 1994; 170: 206-214.
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 206-214
    • Mallard, E.C.1    Williams, C.E.2    Johnston, B.M.3
  • 50
    • 33750205954 scopus 로고    scopus 로고
    • Memory functions of children born with asymmetric intrauterine growth restriction
    • Geva R, Eshel R, Leitner Y, et al. Memory functions of children born with asymmetric intrauterine growth restriction. Brain Res 2006; 1117: 186-194.
    • (2006) Brain Res , vol.1117 , pp. 186-194
    • Geva, R.1    Eshel, R.2    Leitner, Y.3
  • 51
    • 0037370914 scopus 로고    scopus 로고
    • Axonal damage: A key predictor of outcome in human CNS diseases
    • Medana IM, Esiri MM,. Axonal damage: a key predictor of outcome in human CNS diseases. Brain 2003; 126: 515-530.
    • (2003) Brain , vol.126 , pp. 515-530
    • Medana, I.M.1    Esiri, M.M.2
  • 52
    • 77954383520 scopus 로고    scopus 로고
    • Retrograde axonal transport: Pathways to cell death?
    • Perlson E, Maday S, Fu MM, et al. Retrograde axonal transport: pathways to cell death? Trends Neurosci 2010; 33: 335-344.
    • (2010) Trends Neurosci , vol.33 , pp. 335-344
    • Perlson, E.1    Maday, S.2    Fu, M.M.3
  • 53
    • 77249162118 scopus 로고    scopus 로고
    • Axon degeneration: Mechanisms and implications of a distinct program from cell death
    • Yan T, Feng Y, Zhai Q,. Axon degeneration: mechanisms and implications of a distinct program from cell death. Neurochem Int 2010; 56: 529-534.
    • (2010) Neurochem Int , vol.56 , pp. 529-534
    • Yan, T.1    Feng, Y.2    Zhai, Q.3
  • 54
    • 84859723922 scopus 로고    scopus 로고
    • The instrumented fetal sheep as a model of cerebral white matter injury in the premature infant
    • Back SA, Riddle A, Dean J, et al. The instrumented fetal sheep as a model of cerebral white matter injury in the premature infant. Neurotherapeutics 2012; 9: 359-370.
    • (2012) Neurotherapeutics , vol.9 , pp. 359-370
    • Back, S.A.1    Riddle, A.2    Dean, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.