메뉴 건너뛰기




Volumn 34, Issue 6, 2013, Pages 543-551

Mechanisms of melatonin-induced protection in the brain of late gestation fetal sheep in response to hypoxia

Author keywords

Fetal brain; Melatonin; Neuroprotection; Sheep; Umbilical cord occlusion

Indexed keywords

LIPID; MELATONIN; SILASTIC;

EID: 84874006827     PISSN: 03785866     EISSN: 14219859     Source Type: Journal    
DOI: 10.1159/000346323     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 0025350138 scopus 로고
    • Experimental biology of cerebral hypoxia-ischemia: Relation to perinatal brain damage
    • Vannucci RC: Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. Pediatr Res 1990; 27: 317-326.
    • (1990) Pediatr Res , vol.27 , pp. 317-326
    • Vannucci, R.C.1
  • 2
    • 0035215904 scopus 로고    scopus 로고
    • Longterm developmental outcome of asphyxiated term neonates
    • Dilenge ME, Majnemer A, Shevell MI: Longterm developmental outcome of asphyxiated term neonates. J Child Neurol 2001; 16: 781-792.
    • (2001) J Child Neurol , vol.16 , pp. 781-792
    • Dilenge, M.E.1    Majnemer, A.2    Shevell, M.I.3
  • 3
    • 2342511077 scopus 로고    scopus 로고
    • Animal models of hypoxic-ischemic brain damage in the newborn
    • Yager JY: Animal models of hypoxic-ischemic brain damage in the newborn. Semin Pediatr Neurol 2004; 11: 31-46.
    • (2004) Semin Pediatr Neurol , vol.11 , pp. 31-46
    • Yager, J.Y.1
  • 4
    • 1942437616 scopus 로고    scopus 로고
    • Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion
    • Castillo-Melendez M, Chow JA, Walker DW: Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatr Res 2004; 55: 864-871.
    • (2004) Pediatr Res , vol.55 , pp. 864-871
    • Castillo-Melendez, M.1    Chow, J.A.2    Walker, D.W.3
  • 5
    • 23244440004 scopus 로고    scopus 로고
    • Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion
    • Miller SL, Yan EB, Castillo-Melendez M, Jenkin G, Walker DW: Melatonin provides neuroprotection in the late-gestation fetal sheep brain in response to umbilical cord occlusion. Dev Neurosci 2005; 27: 200-210.
    • (2005) Dev Neurosci , vol.27 , pp. 200-210
    • Miller, S.L.1    Yan, E.B.2    Castillo-Melendez, M.3    Jenkin, G.4    Walker, D.W.5
  • 6
    • 69249249242 scopus 로고    scopus 로고
    • Fetal hypoxia insults and patterns of brain injury: Insights from animal models
    • Gunn AJ, Bennet L: Fetal hypoxia insults and patterns of brain injury: insights from animal models. Clin Perinatol 2009; 36: 579-593.
    • (2009) Clin Perinatol , vol.36 , pp. 579-593
    • Gunn, A.J.1    Bennet, L.2
  • 7
    • 0028204030 scopus 로고
    • Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation
    • Mallard EC, Williams CE, Johnston BM, Gluckman PD: Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation. Am J Obstet Gynecol 1994; 170: 206-214.
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 206-214
    • Mallard, E.C.1    Williams, C.E.2    Johnston, B.M.3    Gluckman, P.D.4
  • 10
    • 0034770283 scopus 로고    scopus 로고
    • Neurobiology of periventricular leukomalacia in the premature infant
    • Volpe JJ: Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res 2001; 50: 553-562.
    • (2001) Pediatr Res , vol.50 , pp. 553-562
    • Volpe, J.J.1
  • 11
    • 0037321714 scopus 로고    scopus 로고
    • White matter injury following systemic endotoxemia or asphyxia in the fetal sheep
    • Mallard C, Welin AK, Peebles D, Hagberg H, Kjellmer I: White matter injury following systemic endotoxemia or asphyxia in the fetal sheep. Neurochem Res 2003; 28: 215-223.
    • (2003) Neurochem Res , vol.28 , pp. 215-223
    • Mallard, C.1    Welin, A.K.2    Peebles, D.3    Hagberg, H.4    Kjellmer, I.5
  • 12
    • 0035101941 scopus 로고    scopus 로고
    • Perinatal brain injury: From pathogenesis to neuroprotection
    • Volpe JJ: Perinatal brain injury: from pathogenesis to neuroprotection. Ment Retard Dev Disabil Res Rev 2001; 7: 56-64.
    • (2001) Ment Retard Dev Disabil Res Rev , vol.7 , pp. 56-64
    • Volpe, J.J.1
  • 13
    • 34249018018 scopus 로고    scopus 로고
    • Inhibition of neurosteroid synthesis increases asphyxia- induced brain injury in the late gestation fetal sheep
    • Yawno T, Yan EB, Walker DW, Hirst JJ: Inhibition of neurosteroid synthesis increases asphyxia- induced brain injury in the late gestation fetal sheep. Neuroscience 2007; 146: 1726-1733.
    • (2007) Neuroscience , vol.146 , pp. 1726-1733
    • Yawno, T.1    Yan, E.B.2    Walker, D.W.3    Hirst, J.J.4
  • 14
    • 7444267966 scopus 로고    scopus 로고
    • Neonatal brain injury
    • Ferriero DM: Neonatal brain injury. N Engl J Med 2004; 351: 1985-1995.
    • (2004) N Engl J Med , vol.351 , pp. 1985-1995
    • Ferriero, D.M.1
  • 17
    • 59149092032 scopus 로고    scopus 로고
    • Oxidative stress of the newborn in the preand postnatal period and the clinical utility of melatonin
    • Gitto E, Pellegrino S, Gitto P, Barberi I, Reiter RJ: Oxidative stress of the newborn in the preand postnatal period and the clinical utility of melatonin. J Pineal Res 2009; 46: 128-139.
    • (2009) J Pineal Res , vol.46 , pp. 128-139
    • Gitto, E.1    Pellegrino, S.2    Gitto, P.3    Barberi, I.4    Reiter, R.J.5
  • 18
    • 0030021846 scopus 로고    scopus 로고
    • Mechanisms of tissue injury by oxygen radicals: Implications for neonatal disease
    • Saugstad OD: Mechanisms of tissue injury by oxygen radicals: implications for neonatal disease. Acta Paediatr 1996; 85: 1-4.
    • (1996) Acta Paediatr , vol.85 , pp. 1-4
    • Saugstad, O.D.1
  • 19
    • 84856822915 scopus 로고    scopus 로고
    • Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period
    • Aversa S, Pellegrino S, Barberi I, Reiter RJ, Gitto E: Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. J Matern Fetal Neonatal Med 2012; 25: 207-221.
    • (2012) J Matern Fetal Neonatal Med , vol.25 , pp. 207-221
    • Aversa, S.1    Pellegrino, S.2    Barberi, I.3    Reiter, R.J.4    Gitto, E.5
  • 20
    • 33846463411 scopus 로고    scopus 로고
    • Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion
    • Welin AK, Svedin P, Lapatto R, Sultan B, Hagberg H, Gressens P, Kjellmer I, Mallard C: Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion. Pediatr Res 2007; 61: 153-158.
    • (2007) Pediatr Res , vol.61 , pp. 153-158
    • Welin, A.K.1    Svedin, P.2    Lapatto, R.3    Sultan, B.4    Hagberg, H.5    Gressens, P.6    Kjellmer, I.7    Mallard, C.8
  • 23
    • 23244440004 scopus 로고    scopus 로고
    • Melatonin protects against hydroxyl radical induced damage in a fetal sheep model of acute asphyxia
    • Miller SL, Yan E, Castillo-Melendez M, Jenkin G, Walker DW: Melatonin protects against hydroxyl radical induced damage in a fetal sheep model of acute asphyxia. Dev Neurosci 2005; 27: 200-210.
    • (2005) Dev Neurosci , vol.27 , pp. 200-210
    • Miller, S.L.1    Yan, E.2    Castillo-Melendez, M.3    Jenkin, G.4    Walker, D.W.5
  • 24
    • 7644221985 scopus 로고    scopus 로고
    • Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain
    • Watanabe K, Wakatsuki A, Shinohara K, Ikenoue N, Yokota K, Fukaya T: Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain. J Pineal Res 2004; 37: 276-280.
    • (2004) J Pineal Res , vol.37 , pp. 276-280
    • Watanabe, K.1    Wakatsuki, A.2    Shinohara, K.3    Ikenoue, N.4    Yokota, K.5    Fukaya, T.6
  • 25
    • 0034889907 scopus 로고    scopus 로고
    • Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain
    • Wakatsuki A, Okatani Y, Shinohara K, Ikenoue N, Fukaya T: Melatonin protects against ischemia/reperfusion-induced oxidative damage to mitochondria in fetal rat brain. J Pineal Res 2001; 31: 167-172.
    • (2001) J Pineal Res , vol.31 , pp. 167-172
    • Wakatsuki, A.1    Okatani, Y.2    Shinohara, K.3    Ikenoue, N.4    Fukaya, T.5
  • 26
    • 70849099076 scopus 로고    scopus 로고
    • Therapeutic effects of maternal melatonin administration on ischemia/reperfusion- induced oxidative cerebral damage in neonatal rats
    • Hamada F, Watanabe K, Wakatsuki A, Nagai R, Shinohara K, Hayashi Y, Imamura R, Fukaya T: Therapeutic effects of maternal melatonin administration on ischemia/reperfusion- induced oxidative cerebral damage in neonatal rats. Neonatology 2010; 98: 33-40.
    • (2010) Neonatology , vol.98 , pp. 33-40
    • Hamada, F.1    Watanabe, K.2    Wakatsuki, A.3    Nagai, R.4    Shinohara, K.5    Hayashi, Y.6    Imamura, R.7    Fukaya, T.8
  • 27
    • 83555166114 scopus 로고    scopus 로고
    • Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury
    • Koh PO: Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury. J Pineal Res 2012; 52: 57-61.
    • (2012) J Pineal Res , vol.52 , pp. 57-61
    • Koh, P.O.1
  • 28
    • 64649086387 scopus 로고    scopus 로고
    • Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy
    • Richter HG, Hansell JA, Raut S, Giussani DA: Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. J Pineal Res 2009; 46: 357-364.
    • (2009) J Pineal Res , vol.46 , pp. 357-364
    • Richter, H.G.1    Hansell, J.A.2    Raut, S.3    Giussani, D.A.4
  • 29
    • 78549282095 scopus 로고    scopus 로고
    • Anti-inflammatory activity of melatonin in central nervous system
    • Esposito E, Cuzzocrea S: Anti-inflammatory activity of melatonin in central nervous system. Curr Neuropharmacol 2010; 8: 228-242.
    • (2010) Curr Neuropharmacol , vol.8 , pp. 228-242
    • Esposito, E.1    Cuzzocrea, S.2
  • 30
    • 1942469523 scopus 로고    scopus 로고
    • Cerebrovascular responses in the fetal sheep brain to low-dose endotoxin
    • Yan E, Castillo-Melendez M, Nicholls T, Hirst J, Walker D: Cerebrovascular responses in the fetal sheep brain to low-dose endotoxin. Pediatr Res 2004; 55: 855-863.
    • (2004) Pediatr Res , vol.55 , pp. 855-863
    • Yan, E.1    Castillo-Melendez, M.2    Nicholls, T.3    Hirst, J.4    Walker, D.5
  • 31
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • Galano A, Tan DX, Reiter RJ: Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011; 51: 1-16.
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 32
    • 0028618440 scopus 로고
    • Melatonin - A highly potent endogenous radical scavenger and electron donor: New aspects of the oxidation chemistry of this indole accessed in vitro
    • Poeggeler B, Saarela S, Reiter RJ, Tan DX, Chen LD, Manchester LC, Barlow-Walden LR: Melatonin - a highly potent endogenous radical scavenger and electron donor: new aspects of the oxidation chemistry of this indole accessed in vitro. Ann NY Acad Sci 1994; 738: 419-420.
    • (1994) Ann NY Acad Sci , vol.738 , pp. 419-420
    • Poeggeler, B.1    Saarela, S.2    Reiter, R.J.3    Tan, D.X.4    Chen, L.D.5    Manchester, L.C.6    Barlow-Walden, L.R.7
  • 33
    • 0034648748 scopus 로고    scopus 로고
    • Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain
    • Urabe T, Yamasaki Y, Hattori N, Yoshikawa M, Uchida K, Mizuno Y: Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain. Neuroscience 2000; 100: 241-250.
    • (2000) Neuroscience , vol.100 , pp. 241-250
    • Urabe, T.1    Yamasaki, Y.2    Hattori, N.3    Yoshikawa, M.4    Uchida, K.5    Mizuno, Y.6
  • 35
    • 1942437616 scopus 로고    scopus 로고
    • Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion
    • Castillo-Melendez M, Chow JA, Walker DW: Lipid peroxidation, caspase-3 immunoreactivity, and pyknosis in late-gestation fetal sheep brain after umbilical cord occlusion. Pediatr Res 2004; 55: 864-871.
    • (2004) Pediatr Res , vol.55 , pp. 864-871
    • Castillo-Melendez, M.1    Chow, J.A.2    Walker, D.W.3
  • 36
    • 36248945038 scopus 로고    scopus 로고
    • Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as 'continuum' phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain
    • Northington FJ, Zelaya ME, O'Riordan DP, Blomgren K, Flock DL, Hagberg H, Ferriero DM, Martin LJ: Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as 'continuum' phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain. Neuroscience 2007; 149: 822-833.
    • (2007) Neuroscience , vol.149 , pp. 822-833
    • Northington, F.J.1    Zelaya, M.E.2    O'Riordan, D.P.3    Blomgren, K.4    Flock, D.L.5    Hagberg, H.6    Ferriero, D.M.7    Martin, L.J.8
  • 37
    • 0035742794 scopus 로고    scopus 로고
    • Neurodegeneration in the thalamus following neonatal hypoxia-ischemia is programmed cell death
    • Northington FJ, Ferriero DM, Martin LJ: Neurodegeneration in the thalamus following neonatal hypoxia-ischemia is programmed cell death. Dev Neurosci 2001; 23: 186-191.
    • (2001) Dev Neurosci , vol.23 , pp. 186-191
    • Northington, F.J.1    Ferriero, D.M.2    Martin, L.J.3
  • 38
    • 84859723922 scopus 로고    scopus 로고
    • The instrumented fetal sheep as a model of cerebral white matter injury in the premature infant
    • Back SA, Riddle A, Dean J, Hohimer AR: The instrumented fetal sheep as a model of cerebral white matter injury in the premature infant. Neurotherapeutics 2012; 9: 359-370.
    • (2012) Neurotherapeutics , vol.9 , pp. 359-370
    • Back, S.A.1    Riddle, A.2    Dean, J.3    Hohimer, A.R.4
  • 39
    • 33745700290 scopus 로고    scopus 로고
    • Perinatal white matter injury: The changing spectrum of pathology and emerging insights into pathogenetic mechanisms
    • Back SA: Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms. Ment Retard Dev Disabil Res Rev 2006; 12: 129-140.
    • (2006) Ment Retard Dev Disabil Res Rev , vol.12 , pp. 129-140
    • Back, S.A.1
  • 40
    • 33748076104 scopus 로고    scopus 로고
    • Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury
    • Back SA, Riddle A, Hohimer AR: Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury. J Child Neurol 2006; 21: 582-589.
    • (2006) J Child Neurol , vol.21 , pp. 582-589
    • Back, S.A.1    Riddle, A.2    Hohimer, A.R.3
  • 42
    • 0033163393 scopus 로고    scopus 로고
    • Is NF-κB the sensor of oxidative stress?
    • Li N, Karin M: Is NF-κB the sensor of oxidative stress? FASEB J 1999; 13: 1137-1143.
    • (1999) FASEB J , vol.13 , pp. 1137-1143
    • Li, N.1    Karin, M.2
  • 43
    • 24144473653 scopus 로고    scopus 로고
    • Oxidative and antioxidative potential of brain microglial cells
    • Dringen R: Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal 2005; 7: 1223-1233.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1223-1233
    • Dringen, R.1
  • 44
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: An overview: Structure, regulation, and clinical implications
    • Ballabh P, Braun A, Nedergaard M: The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis 2004; 16: 1-13.
    • (2004) Neurobiol Dis , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 45
    • 0036319335 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions and blood-brain barrier permeability
    • Abbott NJ: Astrocyte-endothelial interactions and blood-brain barrier permeability. J Anat 2002; 200: 629-638.
    • (2002) J Anat , vol.200 , pp. 629-638
    • Abbott, N.J.1
  • 46
    • 51249118951 scopus 로고    scopus 로고
    • Melatonin attenuates hypoxia-induced ultrastructural changes and increased vascular permeability in the developing hippocampus
    • Kaur C, Sivakumar V, Lu J, Tang FR, Ling EA: Melatonin attenuates hypoxia-induced ultrastructural changes and increased vascular permeability in the developing hippocampus. Brain Pathol 2008; 18: 533-547.
    • (2008) Brain Pathol , vol.18 , pp. 533-547
    • Kaur, C.1    Sivakumar, V.2    Lu, J.3    Tang, F.R.4    Ling, E.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.