Curcumol from Rhizoma Curcumae suppresses epileptic seizure by facilitation of GABA(A) receptors

Neuropharmacology

Volumn 81, Issue , 2014, Pages 244-255

  Ding, Jing ^a,b   Wang, Jing Jing ^b   Huang, Chen ^b   Wang, Li ^b   Deng, Shining ^b   Xu, Tian Le ^b   Ge, Wei Hong ^a   Li, Wei Guang ^b   Li, Fei ^b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Curcumol; Epilepsy; GABA

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA5; ANTICONVULSIVE AGENT; CURCUMOL; KAINIC ACID; PENTETRAZOLE; PLANT EXTRACT; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; GLUTAMIC ACID; SESQUITERPENE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CURCUMA; DISEASE PREDISPOSITION; DRUG EFFECT; EMBRYO; EPILEPTIC DISCHARGE; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LATENT PERIOD; LOCOMOTION; MALE; MORTALITY; MOUSE; NERVE EXCITABILITY; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHIZOME; SEIZURE; SYNAPTIC INHIBITION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; EPILEPSY; EXPLORATORY BEHAVIOR; INHIBITORY POSTSYNAPTIC POTENTIAL; MEMBRANE POTENTIAL; METABOLISM; NERVE CELL;

ANIMALS; ANTICONVULSANTS; CELLS, CULTURED; CURCUMA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; EXPLORATORY BEHAVIOR; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIALS; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; NEURONS; RECEPTORS, GABA-A; SESQUITERPENES;

EID: 84896135193     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.02.009     Document Type: Article

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