Alpha-asarone from Acorus gramineus alleviates epilepsy by modulating A-Type GABA receptors

Neuropharmacology

Volumn 65, Issue , 2013, Pages 1-11

  Huang, Chen ^a,c   Li, Wei Guang ^c   Zhang, Xiao Bing ^b   Wang, Li ^a   Xu, Tian Le ^c   Wu, Dazheng ^a   Li, Yong ^c  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Asarone; Epilepsy; GABA; GABAA receptor; Tonic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA ASARONE; BICUCULLINE; KAINIC ACID; MAGNESIUM; PENTETRAZOLE; PICROTOXIN; STRYCHNINE;

ACORUS; ACORUS GRAMINEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CELL ADHESION; CELL CULTURE; CLONIC SEIZURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; DRUG MECHANISM; EPILEPSY; EPILEPTIC DISCHARGE; GABAERGIC TRANSMISSION; HIPPOCAMPUS; IN VIVO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; LATENT PERIOD; MINIATURE ENDPLATE POTENTIAL; MORTALITY; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; TONIC SEIZURE; WHOLE CELL;

ACORUS; ANIMALS; ANISOLES; ANTICONVULSANTS; CELLS, CULTURED; EPILEPSY; HEK293 CELLS; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, INBRED C57BL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 84870896589     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.09.001     Document Type: Article

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