Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

Developmental Biology

Volumn 316, Issue 1, 2008, Pages 87-99

  Hayashi, Toshinori ^a   Kokubo, Hiroki ^b,c   Hartman, Byron H ^d   Ray, Catherine A ^a   Reh, Thomas A ^d   Bermingham McDonogh, Olivia ^a,d  

^a Virginia Merrill Bloedel Hearing Research Center   (United States)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cochlea; Hair cell; Hesr3; Hey1; Hey2; Hey3; Inner ear; Notch; Prosensory

Indexed keywords

CELL CYCLE PROTEIN; JAGGED1; NOTCH RECEPTOR; PROTEIN HESR1; PROTEIN HESR2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; COCHLEA; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; HAIR CELL; IN SITU HYBRIDIZATION; MOUSE; NEUROEPITHELIUM; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION;

EID: 40949091386     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.01.006     Document Type: Article

References (44)

1. Abello G., et al. Early regionalization of the otic placode and its regulation by the Notch signaling pathway. Mech. Dev. 124 (2007) 631-645
2. Bermingham-McDonogh O., et al. Expression of Prox1 during mouse cochlear development. J. Comp. Neurol. 496 (2006) 172-186
3. Bray S.J. Notch signalling: a simple pathway becomes complex. Nat. Rev., Mol. Cell Biol. 7 (2006) 678-689
4. Brooker R., et al. Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development 133 (2006) 1277-1286
5. Brou C., et al. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol. Cell 5 (2000) 207-216
6. Chen P., and Segil N. p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti. Development 126 (1999) 1581-1590
7. Daudet N., and Lewis J. Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation. Development 132 (2005) 541-551
8. Daudet N., et al. Notch signalling is needed to maintain, but not to initiate, the formation of prosensory patches in the chick inner ear. Development 134 (2007) 2369-2378
9. Del Monte G., et al. Monitoring Notch1 activity in development: evidence for a feedback regulatory loop. Dev. Dyn. 236 (2007) 2594-2614
10. Ebinu J.O., and Yankner B.A. A RIP tide in neuronal signal transduction. Neuron 34 (2002) 499-502
11. Fischer A., and Gessler M. Hey genes in cardiovascular development. Trends Cardiovasc. Med. 13 (2003) 221-226
12. Fischer A., and Gessler M. Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res. 35 (2007) 4583-4596
13. Fischer A., et al. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 18 (2004) 901-911
14. Hartman B.H., et al. Dll3 is expressed in developing hair cells in the mammalian cochlea. Dev. Dyn. 236 (2007) 2875-2883
15. Hayashi T., et al. Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev. Dyn. 236 (2007) 525-533
16. Iso T., et al. HES and HERP families: multiple effectors of the Notch signaling pathway. J. Cell. Physiol. 194 (2003) 237-255
17. Kelley M.W. Regulation of cell fate in the sensory epithelia of the inner ear. Nat. Rev., Neurosci. 7 (2006) 837-849
18. Kiernan A.E., et al. The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 132 (2005) 4353-4362
19. Kiernan A.E., et al. The notch ligand jAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet. 2 (2006) e4
20. Kitagawa M., et al. A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol. Cell. Biol. 21 (2001) 4337-4346
21. Kokubo H., et al. Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction. Circ. Res. 95 (2004) 540-547
22. Kokubo H., et al. Hesr, a mediator of the Notch signaling, functions in heart and vessel development. Trends Cardiovasc. Med. 15 (2005) 190-194
23. Kokubo H., et al. Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev. Biol. 278 (2005) 301-309
24. Lai E.C. Notch signaling: control of cell communication and cell fate. Development 131 (2004) 965-973
25. Lanford P.J., et al. Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat. Genet. 21 (1999) 289-292
26. Lanford P.J., et al. Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice. J. Assoc. Res. Otolaryngol. 1 (2000) 161-171
27. Lee Y.S., et al. A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development. Development 133 (2006) 2817-2826
28. Leimeister C., et al. Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis. Mech. Dev. 85 (1999) 173-177
29. Lewis A.K., et al. Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear. Mech. Dev. 78 (1998) 159-163
30. Louvi A., and Artavanis-Tsakonas S. Notch signalling in vertebrate neural development. Nat. Rev., Neurosci. 7 (2006) 93-102
31. Maillard I., et al. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J. Exp. Med. 203 (2006) 2239-2245
32. Morrison A., et al. Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear. Mech. Dev. 84 (1999) 169-172
33. Murata J., et al. Mapping of notch activation during cochlear development in mice: Implications for determination of prosensory domain and cell fate diversification. J. Comp. Neurol. 497 (2006) 502-518
34. Nam Y., et al. Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. J. Biol. Chem. 278 (2003) 21232-21239
35. Schweisguth F., and Posakony J.W. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell 69 (1992) 1199-1212
36. Takebayashi S., et al. Multiple roles of Notch signaling in cochlear development. Dev. Biol. 307 (2007) 165-178
37. Tang L.S., et al. Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear. Gene Expr. Patterns 5 (2005) 587-592
38. Theiler K. The House Mouse: Atlas of Mouse Development (1989), Springer-Verlag, New York
39. Tsai H., et al. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Hum. Mol. Genet. 10 (2001) 507-512
40. Weng A.P., et al. Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol. Cell. Biol. 23 (2003) 655-664
41. Wu L., et al. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 26 (2000) 484-489
42. Yamamoto N., et al. Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J. Mol. Med. 84 (2006) 37-45
43. Zheng J.L., et al. Hes1 is a negative regulator of inner ear hair cell differentiation. Development 127 (2000) 4551-4560
44. Zine A., et al. Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J. Neurosci. 21 (2001) 4712-4720