-
2
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
F. Macian NFAT proteins: key regulators of T-cell development and function Nat. Rev. Immunol. 5 2005 472 484
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
3
-
-
77956175013
-
NFAT, immunity and cancer: A transcription factor comes of age
-
M.R. Muller, and A. Rao NFAT, immunity and cancer: a transcription factor comes of age Nat. Rev. Immunol. 10 2010 645 656
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 645-656
-
-
Muller, M.R.1
Rao, A.2
-
4
-
-
80054933395
-
The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
-
Z. Liu, J. Lee, S. Krummey, W. Lu, H. Cai, and M.J. Lenardo The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease Nat. Immunol. 12 2011 1063 1070
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1063-1070
-
-
Liu, Z.1
Lee, J.2
Krummey, S.3
Lu, W.4
Cai, H.5
Lenardo, M.J.6
-
5
-
-
84884608815
-
Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter
-
H.W. Tsao, T.S. Tai, W. Tseng, H.H. Chang, R. Grenningloh, S.C. Miaw, and I.C. Ho Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter Proc. Natl. Acad. Sci. USA 110 2013 15776 15781
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 15776-15781
-
-
Tsao, H.W.1
Tai, T.S.2
Tseng, W.3
Chang, H.H.4
Grenningloh, R.5
Miaw, S.C.6
Ho, I.C.7
-
6
-
-
80051694778
-
Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid
-
S.K. Singh, S. Baumgart, G. Singh, A.O. Konig, K. Reutlinger, L.C. Hofbauer, P. Barth, T.M. Gress, G. Lomberk, R. Urrutia, M.E. Fernandez-Zapico, and V. Ellenrieder Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid J. Biol. Chem. 286 2011 28761 28771
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28761-28771
-
-
Singh, S.K.1
Baumgart, S.2
Singh, G.3
Konig, A.O.4
Reutlinger, K.5
Hofbauer, L.C.6
Barth, P.7
Gress, T.M.8
Lomberk, G.9
Urrutia, R.10
Fernandez-Zapico, M.E.11
Ellenrieder, V.12
-
7
-
-
84884234601
-
USP18 inhibits NF-kappaB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex
-
X. Liu, H. Li, B. Zhong, M. Blonska, S. Gorjestani, M. Yan, Q. Tian, D.E. Zhang, X. Lin, and C. Dong USP18 inhibits NF-kappaB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex J. Exp. Med. 210 2013 1575 1590
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1575-1590
-
-
Liu, X.1
Li, H.2
Zhong, B.3
Blonska, M.4
Gorjestani, S.5
Yan, M.6
Tian, Q.7
Zhang, D.E.8
Lin, X.9
Dong, C.10
-
8
-
-
84867729539
-
Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25
-
B. Zhong, X. Liu, X. Wang, S.H. Chang, A. Wang, J.M. Reynolds, and C. Dong Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25 Nat. Immunol. 13 2012 1110 1117
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1110-1117
-
-
Zhong, B.1
Liu, X.2
Wang, X.3
Chang, S.H.4
Wang, A.5
Reynolds, J.M.6
Dong, C.7
-
9
-
-
84882592280
-
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity
-
J. van Loosdregt, V. Fleskens, J. Fu, A.B. Brenkman, C.P. Bekker, C.E. Pals, J. Meerding, C.R. Berkers, J. Barbi, A. Grone, A.J. Sijts, M.M. Maurice, E. Kalkhoven, B.J. Prakken, H. Ovaa, F. Pan, D.M. Zaiss, and P.J. Coffer Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity Immunity 39 2013 259 271
-
(2013)
Immunity
, vol.39
, pp. 259-271
-
-
Van Loosdregt, J.1
Fleskens, V.2
Fu, J.3
Brenkman, A.B.4
Bekker, C.P.5
Pals, C.E.6
Meerding, J.7
Berkers, C.R.8
Barbi, J.9
Grone, A.10
Sijts, A.J.11
Maurice, M.M.12
Kalkhoven, E.13
Prakken, B.J.14
Ovaa, H.15
Pan, F.16
Zaiss, D.M.17
Coffer, P.J.18
-
10
-
-
84875979211
-
Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3
-
J. Zhang, C. Chen, X. Hou, Y. Gao, F. Lin, J. Yang, Z. Gao, L. Pan, L. Tao, C. Wen, Z. Yao, A. Tsun, G. Shi, and B. Li Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3 J. Biol. Chem. 288 2013 9373 9382
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 9373-9382
-
-
Zhang, J.1
Chen, C.2
Hou, X.3
Gao, Y.4
Lin, F.5
Yang, J.6
Gao, Z.7
Pan, L.8
Tao, L.9
Wen, C.10
Yao, Z.11
Tsun, A.12
Shi, G.13
Li, B.14
-
11
-
-
38149078715
-
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression
-
X.Y. Zhang, M. Varthi, S.M. Sykes, C. Phillips, C. Warzecha, W. Zhu, A. Wyce, A.W. Thorne, S.L. Berger, and S.B. McMahon The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression Mol. Cell 29 2008 102 111
-
(2008)
Mol. Cell
, vol.29
, pp. 102-111
-
-
Zhang, X.Y.1
Varthi, M.2
Sykes, S.M.3
Phillips, C.4
Warzecha, C.5
Zhu, W.6
Wyce, A.7
Thorne, A.W.8
Berger, S.L.9
McMahon, S.B.10
-
12
-
-
32944480206
-
The expression patterns of deubiquitinating enzymes, USP22 and Usp22
-
H.J. Lee, M.S. Kim, J.M. Shin, T.J. Park, H.M. Chung, and K.H. Baek The expression patterns of deubiquitinating enzymes, USP22 and Usp22 Gene Expr. Patterns 6 2006 277 284
-
(2006)
Gene Expr. Patterns
, vol.6
, pp. 277-284
-
-
Lee, H.J.1
Kim, M.S.2
Shin, J.M.3
Park, T.J.4
Chung, H.M.5
Baek, K.H.6
-
13
-
-
80052281618
-
USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1
-
B.S. Atanassov, and S.Y. Dent USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1 EMBO Rep. 12 2011 924 930
-
(2011)
EMBO Rep.
, vol.12
, pp. 924-930
-
-
Atanassov, B.S.1
Dent, S.Y.2
-
14
-
-
84861461517
-
USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development
-
Z. Lin, H. Yang, Q. Kong, J. Li, S.M. Lee, B. Gao, H. Dong, J. Wei, J. Song, D.D. Zhang, and D. Fang USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development Mol. Cell 46 2012 484 494
-
(2012)
Mol. Cell
, vol.46
, pp. 484-494
-
-
Lin, Z.1
Yang, H.2
Kong, Q.3
Li, J.4
Lee, S.M.5
Gao, B.6
Dong, H.7
Wei, J.8
Song, J.9
Zhang, D.D.10
Fang, D.11
-
15
-
-
70349440053
-
The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice
-
J. Zhang, S.M. Lee, S. Shannon, B. Gao, W. Chen, A. Chen, R. Divekar, M.W. McBurney, H. Braley-Mullen, H. Zaghouani, and D. Fang The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice J. Clin. Invest. 119 2009 3048 3058
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3048-3058
-
-
Zhang, J.1
Lee, S.M.2
Shannon, S.3
Gao, B.4
Chen, W.5
Chen, A.6
Divekar, R.7
McBurney, M.W.8
Braley-Mullen, H.9
Zaghouani, H.10
Fang, D.11
-
16
-
-
0035129248
-
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
-
S.L. Peng, A.J. Gerth, A.M. Ranger, and L.H. Glimcher NFATc1 and NFATc2 together control both T and B cell activation and differentiation Immunity 14 2001 13 20
-
(2001)
Immunity
, vol.14
, pp. 13-20
-
-
Peng, S.L.1
Gerth, A.J.2
Ranger, A.M.3
Glimcher, L.H.4
-
17
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
P.G. Hogan, L. Chen, J. Nardone, and A. Rao Transcriptional regulation by calcium, calcineurin, and NFAT Genes Dev. 17 2003 2205 2232
-
(2003)
Genes Dev.
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
18
-
-
0035971436
-
Partners in transcription: NFAT and AP-1
-
F. Macian, C. Lopez-Rodriguez, and A. Rao Partners in transcription: NFAT and AP-1 Oncogene 20 2001 2476 2489
-
(2001)
Oncogene
, vol.20
, pp. 2476-2489
-
-
Macian, F.1
Lopez-Rodriguez, C.2
Rao, A.3
-
19
-
-
0032980432
-
Requirement for transcription factor NFAT in interleukin-2 expression
-
C.W. Chow, M. Rincon, and R.J. Davis Requirement for transcription factor NFAT in interleukin-2 expression Mol. Cell. Biol. 19 1999 2300 2307
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2300-2307
-
-
Chow, C.W.1
Rincon, M.2
Davis, R.J.3
-
20
-
-
0023821516
-
Identification of a putative regulator of early T cell activation genes
-
J.P. Shaw, P.J. Utz, D.B. Durand, J.J. Toole, E.A. Emmel, and G.R. Crabtree Identification of a putative regulator of early T cell activation genes Science 241 1988 202 205
-
(1988)
Science
, vol.241
, pp. 202-205
-
-
Shaw, J.P.1
Utz, P.J.2
Durand, D.B.3
Toole, J.J.4
Emmel, E.A.5
Crabtree, G.R.6
-
21
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
I.E. Wertz, K.M. O'Rourke, H. Zhou, M. Eby, L. Aravind, S. Seshagiri, P. Wu, C. Wiesmann, R. Baker, D.L. Boone, A. Ma, E.V. Koonin, and V.M. Dixit De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling Nature 430 2004 694 699
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
Wu, P.7
Wiesmann, C.8
Baker, R.9
Boone, D.L.10
Ma, A.11
Koonin, E.V.12
Dixit, V.M.13
-
22
-
-
84882395972
-
The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)
-
R.T. Sussman, T.J. Stanek, P. Esteso, J.D. Gearhart, K.E. Knudsen, and S.B. McMahon The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2) J. Biol. Chem. 288 2013 24234 24246
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 24234-24246
-
-
Sussman, R.T.1
Stanek, T.J.2
Esteso, P.3
Gearhart, J.D.4
Knudsen, K.E.5
McMahon, S.B.6
-
23
-
-
45849133054
-
USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A
-
X.Y. Zhang, H.K. Pfeiffer, A.W. Thorne, and S.B. McMahon USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A Cell Cycle 7 2008 1522 1524
-
(2008)
Cell Cycle
, vol.7
, pp. 1522-1524
-
-
Zhang, X.Y.1
Pfeiffer, H.K.2
Thorne, A.W.3
McMahon, S.B.4
-
24
-
-
84863011200
-
Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance
-
B. Gao, Q. Kong, K. Kemp, Y.S. Zhao, and D. Fang Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance Proc. Natl. Acad. Sci. USA 109 2012 899 904
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 899-904
-
-
Gao, B.1
Kong, Q.2
Kemp, K.3
Zhao, Y.S.4
Fang, D.5
-
25
-
-
70350514636
-
NFAT proteins: Emerging roles in cancer progression
-
M. Mancini, and A. Toker NFAT proteins: emerging roles in cancer progression Nat. Rev. Cancer 9 2009 810 820
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 810-820
-
-
Mancini, M.1
Toker, A.2
|