Differential transcytosis and toxicity of the hNGAL receptor ligands cadmium-metallothionein and cadmium-phytochelatin in colon-like Caco-2 cells: Implications for in vivo cadmium toxicity

Toxicology Letters

Volumn 226, Issue 2, 2014, Pages 228-235

  Langelueddecke, Christian ^a   Lee, Wing Kee ^a   Thévenod, Frank ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Cadmium metallothionein; Cadmium phytochelatin; Colon; Lipocalin 2 receptor; Receptor mediated endocytosis; Transcytosis

Indexed keywords

CADMIUM; CADMIUM METALLOTHIONEIN; CADMIUM PHYTOCHELATIN; CATHEPSIN B; METALLOTHIONEIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; NOCODAZOLE; PHYTOCHELATIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; COLON MUCOSA; CONFOCAL MICROSCOPY; CYTOTOXICITY; ENDOCYTOSIS; FLUORESCENCE; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE EPITHELIUM; LYSOSOME; MICROTUBULE ASSEMBLY; MTT ASSAY; PRIORITY JOURNAL; TRANSCYTOSIS;

CADMIUM-METALLOTHIONEIN; CADMIUM-PHYTOCHELATIN; COLON; LIPOCALIN-2 RECEPTOR; RECEPTOR-MEDIATED ENDOCYTOSIS; TRANSCYTOSIS;

ACUTE-PHASE PROTEINS; CACO-2 CELLS; CADMIUM; CATHEPSIN B; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTESTINAL MUCOSA; KINETICS; LIGANDS; LIPOCALINS; LYSOSOMES; METALLOTHIONEIN; PHYTOCHELATINS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; TRANSCYTOSIS; TUBULIN MODULATORS;

EID: 84896039268     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.01.049     Document Type: Article

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