Histone Decacetylase Inhibitors Prevent Mitochondrial Fragmentation and Elicit Early Neuroprotection against MPP+

CNS Neuroscience and Therapeutics

Volumn 20, Issue 4, 2014, Pages 308-316

  Zhu, Min ^a,b   Li, Wen Wei ^a,b   Lu, Chuan Zhen ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Early neuroprotection; Histone deacetylase inhibitors; Mitochondrial fragmentation; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; HISTONE DEACETYLASE INHIBITOR; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; ROTENONE; TRICHOSTATIN A; BAX PROTEIN, HUMAN; CARRIER PROTEIN; GUANOSINE TRIPHOSPHATASE; HYDROXAMIC ACID; MFN1 PROTEIN, HUMAN; MFN2 PROTEIN, HUMAN; NEUROPROTECTIVE AGENT; PROTEIN BAX; UNCOUPLING PROTEIN;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; ENZYME INHIBITION; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FRAGMENTATION; NEUROPROTECTION; PARKINSON DISEASE; PROMOTER REGION; CHEMICALLY INDUCED; DRUG EFFECTS; HUMAN; METABOLISM; MITOCHONDRION; MPTP POISONING; PARKINSONIAN DISORDERS; PHYSIOLOGY; TOXICITY; TUMOR CELL LINE;

1-METHYL-4-PHENYLPYRIDINIUM; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; GTP PHOSPHOHYDROLASES; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MPTP POISONING; NEUROPROTECTIVE AGENTS; PARKINSONIAN DISORDERS; ROTENONE; UNCOUPLING AGENTS;

EID: 84896038598     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12217     Document Type: Article

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