Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3+ Treg-cell formation

European Journal of Immunology

Volumn 44, Issue 3, 2014, Pages 785-793

  Caton, Andrew J ^a   Kropf, Elizabeth ^a   Simons, Donald M ^a   Aitken, Malinda ^a   Weissler, Katherine A ^a   Jordan, Martha S ^b  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Immune regulation; Thymic selection; Tolerance

Indexed keywords

SUPERANTIGEN; TRANSCRIPTION FACTOR FOXP3; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL SELECTION; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; THYMOCYTE;

IMMUNE REGULATION; THYMIC SELECTION; TOLERANCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGEN PRESENTATION; AUTOANTIGENS; AUTOIMMUNITY; CLONAL DELETION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; MUTATION; PEPTIDES; PHENOTYPE; PHOSPHOPROTEINS; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; THYMOCYTES;

EID: 84896036640     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343767     Document Type: Article

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