During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

Journal of Experimental Medicine

Volumn 205, Issue 5, 2008, Pages 1029-1036

  Thompson, Jennifer ^a   Winoto, Astar ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; NUCLEAR PROTEIN; NUCLEAR RECEPTOR NUR77; PROTEIN BCL 2; PROTEIN NOR 1; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STIMULATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE SUBPOPULATION; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; B-LYMPHOCYTES; CELL LINE, TUMOR; DNA-BINDING PROTEINS; FATTY ACIDS, UNSATURATED; HUMANS; IONOMYCIN; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, STEROID; RECEPTORS, THYROID HORMONE; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC;

EID: 43549097825     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20080101     Document Type: Article

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