WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma

Cell Death and Disease

Volumn 4, Issue 9, 2013, Pages

  Tsai, C W ^a   Lai, F J ^b   Sheu, H M ^a   Lin, Y S ^a,c   Chang, T H ^a   Jan, M S ^d   Chen, S M ^a   Hsu, P C ^a   Huang, T T ^a   Huang, T C ^a   Sheen, M C ^e   Chen, S T ^a   Chang, W C ^c,f   Chang, N S ^a,c,g   Hsu, L J ^a,c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^g State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Apoptosis; Autophagy; Chemotherapy; Methotrexate; Tumor suppressor

Indexed keywords

AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 5; BECLIN 1; CASPASE 3; CASPASE 9; MAMMALIAN TARGET OF RAPAMYCIN; METHOTREXATE; MICROTUBULE ASSOCIATED PROTEIN 3; OXIDOREDUCTASE; PROTEIN; S6 KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WW DOMAIN CONTAINING OXIDOREDUCTASE;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER RESISTANCE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY; UPREGULATION;

APOPTOSIS; AUTOPHAGY; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DOWN-REGULATION; HUMANS; METHOTREXATE; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; OXIDOREDUCTASES; PHAGOSOMES; SIGNAL TRANSDUCTION; TONGUE NEOPLASMS; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84884993163     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.308     Document Type: Article

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