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Volumn 13, Issue 1, 2007, Pages 12-22

WW domain-containing oxidoreductase: a candidate tumor suppressor

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ESTROGEN; HYALURONIDASE; OXIDOREDUCTASE; PROTEIN P53; PROTEIN P73; PROTEIN WWOX; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 33845879138     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2006.11.006     Document Type: Article
Times cited : (110)

References (75)
  • 1
    • 0034655131 scopus 로고    scopus 로고
    • WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer
    • Bednarek A.K., et al. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. Cancer Res. 60 (2000) 2140-2145
    • (2000) Cancer Res. , vol.60 , pp. 2140-2145
    • Bednarek, A.K.1
  • 2
    • 17444440946 scopus 로고    scopus 로고
    • Common chromosomal fragile site FRAD16D sequence: identification of the FOR gene spanning FRAD16D and homozygous deletions and translocation breakpoints in cancer cells
    • Ried K., et al. Common chromosomal fragile site FRAD16D sequence: identification of the FOR gene spanning FRAD16D and homozygous deletions and translocation breakpoints in cancer cells. Hum. Mol. Genet. 9 (2000) 1651-1663
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1651-1663
    • Ried, K.1
  • 3
    • 0035793612 scopus 로고    scopus 로고
    • Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity
    • Chang N.-S., et al. Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity. J. Biol. Chem. 276 (2001) 3361-3370
    • (2001) J. Biol. Chem. , vol.276 , pp. 3361-3370
    • Chang, N.-S.1
  • 4
    • 0642283973 scopus 로고    scopus 로고
    • Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses
    • Chang N.-S., et al. Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses. Biochem. Pharmacol. 66 (2003) 1347-1354
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 1347-1354
    • Chang, N.-S.1
  • 5
    • 0346059608 scopus 로고    scopus 로고
    • An opposing view on WWOX protein function as a tumor suppressor
    • Watanabe A., et al. An opposing view on WWOX protein function as a tumor suppressor. Cancer Res. 63 (2003) 8629-8633
    • (2003) Cancer Res. , vol.63 , pp. 8629-8633
    • Watanabe, A.1
  • 6
    • 28544438918 scopus 로고    scopus 로고
    • Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox
    • Mahajan N.P., et al. Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. Cancer Res. 65 (2005) 10514-10523
    • (2005) Cancer Res. , vol.65 , pp. 10514-10523
    • Mahajan, N.P.1
  • 7
    • 24744443035 scopus 로고    scopus 로고
    • HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor
    • Lokeshwar V.B., et al. HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor. Cancer Res. 65 (2005) 7782-7789
    • (2005) Cancer Res. , vol.65 , pp. 7782-7789
    • Lokeshwar, V.B.1
  • 8
    • 3142710158 scopus 로고    scopus 로고
    • Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease
    • Sze C.-I., et al. Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease. J. Biol. Chem. 279 (2004) 30498-30506
    • (2004) J. Biol. Chem. , vol.279 , pp. 30498-30506
    • Sze, C.-I.1
  • 9
    • 13244271314 scopus 로고    scopus 로고
    • 17β-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo
    • Chang N.-S., et al. 17β-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo. Oncogene 24 (2005) 714-723
    • (2005) Oncogene , vol.24 , pp. 714-723
    • Chang, N.-S.1
  • 10
    • 0036266065 scopus 로고    scopus 로고
    • The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1
    • Krummel K.A., et al. The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1. Genes Chromosomes Cancer 34 (2002) 154-167
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 154-167
    • Krummel, K.A.1
  • 11
    • 0034704216 scopus 로고    scopus 로고
    • NeW wrinkles for an old domain
    • Sudol M., and Hunter T. NeW wrinkles for an old domain. Cell 103 (2000) 1001-1004
    • (2000) Cell , vol.103 , pp. 1001-1004
    • Sudol, M.1    Hunter, T.2
  • 12
    • 12144287536 scopus 로고    scopus 로고
    • A map of WW domain family interactions
    • Hu H., et al. A map of WW domain family interactions. Proteomics 4 (2004) 643-655
    • (2004) Proteomics , vol.4 , pp. 643-655
    • Hu, H.1
  • 13
    • 30344454668 scopus 로고    scopus 로고
    • WW or WoW: the WW domains in a union of bliss
    • Sudol M., et al. WW or WoW: the WW domains in a union of bliss. IUBMB Life 57 (2005) 773-778
    • (2005) IUBMB Life , vol.57 , pp. 773-778
    • Sudol, M.1
  • 14
    • 1842763560 scopus 로고    scopus 로고
    • Pinning down cell signaling, cancer and Alzheimer's disease
    • Lu K.P. Pinning down cell signaling, cancer and Alzheimer's disease. Trends Biochem. Sci. 29 (2004) 200-209
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 200-209
    • Lu, K.P.1
  • 15
    • 33748029809 scopus 로고    scopus 로고
    • Pin1 in Alzheimer's disease
    • Butterfield D.A., et al. Pin1 in Alzheimer's disease. J. Neurochem. 98 (2006) 1697-1706
    • (2006) J. Neurochem. , vol.98 , pp. 1697-1706
    • Butterfield, D.A.1
  • 16
    • 0035969860 scopus 로고    scopus 로고
    • Forms and functions of human SDR enzymes
    • Oppermann U.C., et al. Forms and functions of human SDR enzymes. Chem. Biol. Interact. 130-132 (2001) 699-705
    • (2001) Chem. Biol. Interact. , vol.130-132 , pp. 699-705
    • Oppermann, U.C.1
  • 17
    • 20444441575 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-β peptide alcohol dehydrogenase (ABAD)
    • Yan S.D., and Stern D.M. Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-β peptide alcohol dehydrogenase (ABAD). Int. J. Exp. Pathol. 86 (2005) 161-171
    • (2005) Int. J. Exp. Pathol. , vol.86 , pp. 161-171
    • Yan, S.D.1    Stern, D.M.2
  • 18
    • 0038322051 scopus 로고    scopus 로고
    • JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis
    • Chang N.-S., et al. JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis. J. Biol. Chem. 278 (2003) 9195-9202
    • (2003) J. Biol. Chem. , vol.278 , pp. 9195-9202
    • Chang, N.-S.1
  • 19
    • 12144289659 scopus 로고    scopus 로고
    • Functional association between Wwox tumor suppressor protein and p73, a p53 homolog
    • Aqeilan R.I., et al. Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 4401-4406
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4401-4406
    • Aqeilan, R.I.1
  • 20
    • 12344311908 scopus 로고    scopus 로고
    • Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo
    • Chen S.T., et al. Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo. Neuroscience 130 (2005) 397-407
    • (2005) Neuroscience , vol.130 , pp. 397-407
    • Chen, S.T.1
  • 21
    • 0036134649 scopus 로고    scopus 로고
    • A potential role of p53 and WOX1 in mitochondrial apoptosis
    • Chang N.-S. A potential role of p53 and WOX1 in mitochondrial apoptosis. Int. J. Mol. Med. 9 (2002) 19-24
    • (2002) Int. J. Mol. Med. , vol.9 , pp. 19-24
    • Chang, N.-S.1
  • 22
    • 0035890419 scopus 로고    scopus 로고
    • WWOX, the FRA16D gene, behaves as a suppressor of tumor growth
    • Bednarek A.K., et al. WWOX, the FRA16D gene, behaves as a suppressor of tumor growth. Cancer Res. 61 (2001) 8068-8073
    • (2001) Cancer Res. , vol.61 , pp. 8068-8073
    • Bednarek, A.K.1
  • 23
    • 31744449520 scopus 로고    scopus 로고
    • PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction
    • Jin C., et al. PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem. Biophys. Res. Commun. 341 (2006) 784-791
    • (2006) Biochem. Biophys. Res. Commun. , vol.341 , pp. 784-791
    • Jin, C.1
  • 24
    • 1542351221 scopus 로고    scopus 로고
    • Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system
    • Chen S.T., et al. Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system. Neuroscience 124 (2004) 831-839
    • (2004) Neuroscience , vol.124 , pp. 831-839
    • Chen, S.T.1
  • 25
    • 23844466267 scopus 로고    scopus 로고
    • WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo
    • Lai F.J., et al. WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo. Clin. Cancer Res. 11 (2005) 5769-5777
    • (2005) Clin. Cancer Res. , vol.11 , pp. 5769-5777
    • Lai, F.J.1
  • 26
    • 33845900365 scopus 로고    scopus 로고
    • WWOX protein expression in normal human tissues
    • Nunez M.I., et al. WWOX protein expression in normal human tissues. J. Mol. Histol. 31 (2006) 115-125
    • (2006) J. Mol. Histol. , vol.31 , pp. 115-125
    • Nunez, M.I.1
  • 27
    • 30044438229 scopus 로고    scopus 로고
    • WOX1 is essential for TNF-, UV light-, staurosporine-, and p53-mediated cell death and its tyrosine 33 phosphorylated form binds and stabilizes serine 46-phosphorylated p53
    • Chang N.-S., et al. WOX1 is essential for TNF-, UV light-, staurosporine-, and p53-mediated cell death and its tyrosine 33 phosphorylated form binds and stabilizes serine 46-phosphorylated p53. J. Biol. Chem. 280 (2005) 43100-43108
    • (2005) J. Biol. Chem. , vol.280 , pp. 43100-43108
    • Chang, N.-S.1
  • 28
    • 27344455410 scopus 로고    scopus 로고
    • WWOX gene restoration prevents lung cancer growth in vitro and in vivo
    • Fabbri M., et al. WWOX gene restoration prevents lung cancer growth in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 15611-15616
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 15611-15616
    • Fabbri, M.1
  • 29
    • 33746154619 scopus 로고    scopus 로고
    • A role for the WWOX gene in prostate cancer
    • Qin H.R., et al. A role for the WWOX gene in prostate cancer. Cancer Res. 66 (2006) 6477-6481
    • (2006) Cancer Res. , vol.66 , pp. 6477-6481
    • Qin, H.R.1
  • 30
    • 33845391172 scopus 로고    scopus 로고
    • Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity
    • Cantor J.P., et al. Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. Int. J. Cancer 120 (2007) 24-31
    • (2007) Int. J. Cancer , vol.120 , pp. 24-31
    • Cantor, J.P.1
  • 31
    • 33645838382 scopus 로고    scopus 로고
    • Chromosomal fragile sites FRA3B and FRA16D show correlated expression and association with failure of apoptosis in lymphocytes from patients with thyroid cancer
    • Sbrana I., et al. Chromosomal fragile sites FRA3B and FRA16D show correlated expression and association with failure of apoptosis in lymphocytes from patients with thyroid cancer. Genes Chromosomes Cancer 45 (2006) 429-436
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 429-436
    • Sbrana, I.1
  • 32
    • 0035369401 scopus 로고    scopus 로고
    • Fragile and unstable chromosomes in cancer: causes and consequences
    • Richards R.I. Fragile and unstable chromosomes in cancer: causes and consequences. Trends Genet. 17 (2001) 339-345
    • (2001) Trends Genet. , vol.17 , pp. 339-345
    • Richards, R.I.1
  • 33
    • 33644842150 scopus 로고    scopus 로고
    • Tumor necrosis factor ligand-receptor superfamily and arthritis
    • Hsu H.C., et al. Tumor necrosis factor ligand-receptor superfamily and arthritis. Curr. Dir. Autoimmun. 9 (2006) 37-54
    • (2006) Curr. Dir. Autoimmun. , vol.9 , pp. 37-54
    • Hsu, H.C.1
  • 34
    • 8544283814 scopus 로고    scopus 로고
    • Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2γ transcription factor
    • Aqeilan R.I., et al. Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2γ transcription factor. Cancer Res. 64 (2004) 8256-8261
    • (2004) Cancer Res. , vol.64 , pp. 8256-8261
    • Aqeilan, R.I.1
  • 35
    • 23044492008 scopus 로고    scopus 로고
    • WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function
    • Aqeilan R.I., et al. WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function. Cancer Res. 65 (2005) 6764-6772
    • (2005) Cancer Res. , vol.65 , pp. 6764-6772
    • Aqeilan, R.I.1
  • 36
    • 3042784091 scopus 로고    scopus 로고
    • WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins
    • Ludes-Meyers J.H., et al. WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins. Oncogene 23 (2004) 5049-5055
    • (2004) Oncogene , vol.23 , pp. 5049-5055
    • Ludes-Meyers, J.H.1
  • 37
    • 0036346708 scopus 로고    scopus 로고
    • ERM proteins and merlin: integrators at the cell cortex
    • Bretscher A., et al. ERM proteins and merlin: integrators at the cell cortex. Nat. Rev. Mol. Cell Biol. 3 (2002) 586-599
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 586-599
    • Bretscher, A.1
  • 38
    • 0344100087 scopus 로고    scopus 로고
    • WWOX, the common chromosomal fragile site, FRA16D, cancer gene
    • Ludes-Meyers J.H. WWOX, the common chromosomal fragile site, FRA16D, cancer gene. Cytogenet. Genome Res. 100 (2003) 101-110
    • (2003) Cytogenet. Genome Res. , vol.100 , pp. 101-110
    • Ludes-Meyers, J.H.1
  • 39
    • 1942455814 scopus 로고    scopus 로고
    • Common fragile genes
    • Matsuyama A., et al. Common fragile genes. Eur. J. Histochem. 48 (2004) 29-36
    • (2004) Eur. J. Histochem. , vol.48 , pp. 29-36
    • Matsuyama, A.1
  • 40
    • 2442479760 scopus 로고    scopus 로고
    • Alterations of common chromosome fragile sites in hematopoietic malignancies
    • Ishii H., and Furukawa Y. Alterations of common chromosome fragile sites in hematopoietic malignancies. Int. J. Hematol. 79 (2004) 238-242
    • (2004) Int. J. Hematol. , vol.79 , pp. 238-242
    • Ishii, H.1    Furukawa, Y.2
  • 41
    • 30144436775 scopus 로고    scopus 로고
    • Common chromosomal fragile sites and cancer: focus on FRA16D
    • O'Keefe L.V., and Richards R.I. Common chromosomal fragile sites and cancer: focus on FRA16D. Cancer Lett. 232 (2006) 37-47
    • (2006) Cancer Lett. , vol.232 , pp. 37-47
    • O'Keefe, L.V.1    Richards, R.I.2
  • 42
    • 30144438249 scopus 로고    scopus 로고
    • Roles of FHIT and WWOX fragile genes in cancer
    • Iliopoulos D., et al. Roles of FHIT and WWOX fragile genes in cancer. Cancer Lett. 232 (2006) 27-36
    • (2006) Cancer Lett. , vol.232 , pp. 27-36
    • Iliopoulos, D.1
  • 43
    • 30144442771 scopus 로고    scopus 로고
    • Common fragile sites, extremely large genes, neural development and cancer
    • Smith D.I., et al. Common fragile sites, extremely large genes, neural development and cancer. Cancer Lett. 232 (2006) 48-57
    • (2006) Cancer Lett. , vol.232 , pp. 48-57
    • Smith, D.I.1
  • 44
    • 17944378192 scopus 로고    scopus 로고
    • Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma
    • Yakicier M.C., et al. Identification of homozygous deletions at chromosome 16q23 in aflatoxin B1 exposed hepatocellular carcinoma. Oncogene 20 (2001) 5232-5238
    • (2001) Oncogene , vol.20 , pp. 5232-5238
    • Yakicier, M.C.1
  • 45
    • 85047700355 scopus 로고    scopus 로고
    • Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors
    • Driouch K., et al. Alternative transcripts of the candidate tumor suppressor gene, WWOX, are expressed at high levels in human breast tumors. Oncogene 21 (2002) 1832-1840
    • (2002) Oncogene , vol.21 , pp. 1832-1840
    • Driouch, K.1
  • 46
    • 0037089477 scopus 로고    scopus 로고
    • Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma
    • Kuroki T., et al. Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma. Cancer Res. 62 (2002) 2258-2260
    • (2002) Cancer Res. , vol.62 , pp. 2258-2260
    • Kuroki, T.1
  • 47
    • 0037442728 scopus 로고    scopus 로고
    • WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer
    • Yendamuri S., et al. WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer. Cancer Res. 63 (2003) 878-881
    • (2003) Cancer Res. , vol.63 , pp. 878-881
    • Yendamuri, S.1
  • 48
    • 11144354718 scopus 로고    scopus 로고
    • The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis
    • Kuroki T., et al. The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis. Clin. Cancer Res. 10 (2004) 2459-2465
    • (2004) Clin. Cancer Res. , vol.10 , pp. 2459-2465
    • Kuroki, T.1
  • 49
    • 2442589606 scopus 로고    scopus 로고
    • Loss of WWOX expression in gastric carcinoma
    • Aqeilan R.I., et al. Loss of WWOX expression in gastric carcinoma. Clin. Cancer Res. 10 (2004) 3053-3058
    • (2004) Clin. Cancer Res. , vol.10 , pp. 3053-3058
    • Aqeilan, R.I.1
  • 50
    • 31844432243 scopus 로고    scopus 로고
    • Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas
    • Pimenta F.J., et al. Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas. Int. J. Cancer 118 (2006) 1154-1158
    • (2006) Int. J. Cancer , vol.118 , pp. 1154-1158
    • Pimenta, F.J.1
  • 51
    • 0344874589 scopus 로고    scopus 로고
    • Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies
    • Ishii H., et al. Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies. Mol. Cancer Res. 1 (2003) 940-947
    • (2003) Mol. Cancer Res. , vol.1 , pp. 940-947
    • Ishii, H.1
  • 52
    • 27644582835 scopus 로고    scopus 로고
    • Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR
    • Thavathiru E., et al. Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR. Mol. Carcinog. 44 (2005) 174-182
    • (2005) Mol. Carcinog. , vol.44 , pp. 174-182
    • Thavathiru, E.1
  • 53
    • 17144405305 scopus 로고    scopus 로고
    • Components of DNA damage checkpoint pathway regulate UV exposure-dependent alterations of gene expression of FHIT and WWOX at chromosome fragile sites
    • Ishii H., et al. Components of DNA damage checkpoint pathway regulate UV exposure-dependent alterations of gene expression of FHIT and WWOX at chromosome fragile sites. Mol. Cancer Res. 3 (2005) 130-138
    • (2005) Mol. Cancer Res. , vol.3 , pp. 130-138
    • Ishii, H.1
  • 54
    • 32944460958 scopus 로고    scopus 로고
    • WWOX - the FRA16D cancer gene: expression correlation with breast cancer progression and prognosis
    • Pluciennik E., et al. WWOX - the FRA16D cancer gene: expression correlation with breast cancer progression and prognosis. Eur. J. Surg. Oncol. 32 (2006) 153-157
    • (2006) Eur. J. Surg. Oncol. , vol.32 , pp. 153-157
    • Pluciennik, E.1
  • 55
    • 0035949591 scopus 로고    scopus 로고
    • WWOX: a candidate tumor suppressor gene involved in multiple tumor types
    • Paige A., et al. WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 11417-11422
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 11417-11422
    • Paige, A.1
  • 56
    • 33646918047 scopus 로고    scopus 로고
    • Deletion and mutation of WWOX exons 6-8 in human non-small cell lung cancer
    • Zhou Y., et al. Deletion and mutation of WWOX exons 6-8 in human non-small cell lung cancer. J. Huazhong Univ. Sci. Technolog. Med. Sci 25 (2005) 162-165
    • (2005) J. Huazhong Univ. Sci. Technolog. Med. Sci , vol.25 , pp. 162-165
    • Zhou, Y.1
  • 57
    • 22344436709 scopus 로고    scopus 로고
    • WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear
    • Gourley C., et al. WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear. Int. J. Oncol. 26 (2005) 1681-1689
    • (2005) Int. J. Oncol. , vol.26 , pp. 1681-1689
    • Gourley, C.1
  • 58
    • 20144372911 scopus 로고    scopus 로고
    • Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer
    • Iliopoulos D., et al. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene 24 (2005) 1625-1633
    • (2005) Oncogene , vol.24 , pp. 1625-1633
    • Iliopoulos, D.1
  • 59
    • 1842581808 scopus 로고    scopus 로고
    • The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma
    • Guler G., et al. The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma. Cancer 100 (2004) 1605-1614
    • (2004) Cancer , vol.100 , pp. 1605-1614
    • Guler, G.1
  • 60
    • 26944477074 scopus 로고    scopus 로고
    • FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila
    • O'Keefe L.V., et al. FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila. Oncogene 24 (2005) 6590-6596
    • (2005) Oncogene , vol.24 , pp. 6590-6596
    • O'Keefe, L.V.1
  • 61
    • 27644456289 scopus 로고    scopus 로고
    • Death penalty for keratinocytes: apoptosis versus cornification
    • Lippens S., et al. Death penalty for keratinocytes: apoptosis versus cornification. Cell Death Differ. 12 (2005) 1497-1508
    • (2005) Cell Death Differ. , vol.12 , pp. 1497-1508
    • Lippens, S.1
  • 62
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: a model of cell death in the skin
    • Candi E., et al. The cornified envelope: a model of cell death in the skin. Nat. Rev. Mol. Cell Biol. 6 (2005) 328-340
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 328-340
    • Candi, E.1
  • 63
    • 33750072347 scopus 로고    scopus 로고
    • Expression profiling of UVB response in melanocytes identifies a set of p53-target genes
    • Yang G., et al. Expression profiling of UVB response in melanocytes identifies a set of p53-target genes. J. Invest. Dermatol. 126 (2006) 2490-2506
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 2490-2506
    • Yang, G.1
  • 64
    • 0036241593 scopus 로고    scopus 로고
    • The epidemiology of skin cancer
    • Diepgen T.L., and Mahler V. The epidemiology of skin cancer. Br. J. Dermatol. 61 (2002) 1-6
    • (2002) Br. J. Dermatol. , vol.61 , pp. 1-6
    • Diepgen, T.L.1    Mahler, V.2
  • 65
    • 19344370295 scopus 로고    scopus 로고
    • The sunburn cell: regulation of death and survival of the keratinocyte
    • Van Laethem A., et al. The sunburn cell: regulation of death and survival of the keratinocyte. Int. J. Biochem. Cell Biol. 37 (2005) 1547-1553
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 1547-1553
    • Van Laethem, A.1
  • 66
    • 26844437227 scopus 로고    scopus 로고
    • WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome
    • Nunez M.I., et al. WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome. BMC Cancer 5 (2005) 64
    • (2005) BMC Cancer , vol.5 , pp. 64
    • Nunez, M.I.1
  • 67
    • 0040446013 scopus 로고    scopus 로고
    • Hyaluronidases in tissue invasion
    • Csoka T.B., et al. Hyaluronidases in tissue invasion. Invasion Metastasis 17 (1997) 297-311
    • (1997) Invasion Metastasis , vol.17 , pp. 297-311
    • Csoka, T.B.1
  • 68
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 4 (2004) 528-539
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 69
    • 23444445895 scopus 로고    scopus 로고
    • Hyaluronan metabolism: a major paradox in cancer biology
    • Stern R. Hyaluronan metabolism: a major paradox in cancer biology. Pathol. Biol. (Paris) 53 (2005) 372-382
    • (2005) Pathol. Biol. (Paris) , vol.53 , pp. 372-382
    • Stern, R.1
  • 70
    • 0035202430 scopus 로고    scopus 로고
    • The six hyaluronidase-like genes in the human and mouse genomes
    • Csoka A.B., et al. The six hyaluronidase-like genes in the human and mouse genomes. Matrix Biol. 20 (2001) 499-508
    • (2001) Matrix Biol. , vol.20 , pp. 499-508
    • Csoka, A.B.1
  • 71
    • 0032508627 scopus 로고    scopus 로고
    • Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors
    • St Croix B., et al. Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors. Cancer Lett. 131 (1998) 35-44
    • (1998) Cancer Lett. , vol.131 , pp. 35-44
    • St Croix, B.1
  • 72
    • 0036354170 scopus 로고    scopus 로고
    • Expression of PH-20 in normal and neoplastic breast tissue
    • Beech D.J., et al. Expression of PH-20 in normal and neoplastic breast tissue. J. Surg. Res. 103 (2002) 203-207
    • (2002) J. Surg. Res. , vol.103 , pp. 203-207
    • Beech, D.J.1
  • 73
    • 2342661151 scopus 로고    scopus 로고
    • Transforming growth factor-β1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts
    • Chang N.-S. Transforming growth factor-β1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts. BMC Cell Biol. 3 (2002) 8
    • (2002) BMC Cell Biol. , vol.3 , pp. 8
    • Chang, N.-S.1
  • 74
    • 13844281272 scopus 로고    scopus 로고
    • Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status
    • Nunez M.I., et al. Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status. Breast Cancer Res. Treat. 89 (2005) 99-105
    • (2005) Breast Cancer Res. Treat. , vol.89 , pp. 99-105
    • Nunez, M.I.1
  • 75
    • 33748065322 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Itch controls the protein stability of p63
    • Rossi M., et al. The E3 ubiquitin ligase Itch controls the protein stability of p63. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 12753-12758
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 12753-12758
    • Rossi, M.1


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