The Size of the Proteasomal Substrate Determines Whether Its Degradation Will Be Mediated by Mono- or Polyubiquitylation

Molecular Cell

Volumn 48, Issue 1, 2012, Pages 87-97

  Shabek, Nitzan ^a   Herman Bachinsky, Yifat ^a   Buchsbaum, Samuel ^a   Lewinson, Oded ^a   Haj Yahya, Mahmood ^b   Hejjaoui, Mirva ^c   Lashuel, Hilal A ^c   Sommer, Thomas ^d   Brik, Ashraf ^b   Ciechanover, Aaron ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c EPFL   (Switzerland)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PROTEASOME; UBIQUITIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; MONOUBIQUITYLATION; NONHUMAN; POLYUBIQUITYLATION; PROTEIN DEGRADATION; REACTION ANALYSIS; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; UBIQUITINATION;

AMINO ACID SEQUENCE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITINATION;

EID: 84867398821     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.07.011     Document Type: Article

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