Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptions

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 4, 2014, Pages 1065-1074

  Ichihara, Asako ^a   Wang, Zhongzhi ^a   Jinnin, Masatoshi ^a   Izuno, Yuki ^a   Shimozono, Naoki ^a   Yamane, Keitaro ^a   Fujisawa, Akihiko ^a   Moriya, Chikako ^a   Fukushima, Satoshi ^a   Inoue, Yuji ^a   Ihn, Hironobu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

apoptosis; drug eruption; keratinocyte; MicroRNA; serum

Indexed keywords

B CELL LYMPHOMA LEUKEMIA 2 LIKE PROTEIN 10; CASPASE 9; MICRO RNA 18A 5P; MICRORNA; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; APOPTOSIS; ARTICLE; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; DISEASE SEVERITY; DOWN REGULATION; DRUG ERUPTION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; LUCIFERASE ASSAY; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TOXIC EPIDERMAL NECROLYSIS; TRANSIENT TRANSFECTION; UPREGULATION;

APOPTOSIS; DRUG ERUPTION; KERATINOCYTE; MICRORNA; SERUM;

APOPTOSIS; BIOLOGICAL MARKERS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KERATINOCYTES; MICRORNAS; PROTO-ONCOGENE PROTEINS C-BCL-2; SKIN; STEVENS-JOHNSON SYNDROME;

EID: 84895924095     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.09.019     Document Type: Article

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