메뉴 건너뛰기




Volumn 34, Issue 8, 2015, Pages 1064-1072

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

Author keywords

[No Author keywords available]

Indexed keywords

CDKN2A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; SCATTER FACTOR RECEPTOR;

EID: 84895915340     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.29     Document Type: Article
Times cited : (24)

References (50)
  • 2
    • 80052023881 scopus 로고    scopus 로고
    • The neurobiology of gliomas: From cell biology to the development of therapeutic approaches
    • Westphal M, Lamszus K. The neurobiology of gliomas: from cell biology to the development of therapeutic approaches. Nat Rev Neurosci 2011; 12: 495-508.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 495-508
    • Westphal, M.1    Lamszus, K.2
  • 3
    • 70350449411 scopus 로고    scopus 로고
    • Advances in the genetics of glioblastoma: Are we reaching critical mass
    • Purow B, Schiff D. Advances in the genetics of glioblastoma: are we reaching critical mass Nat Rev Neurol 2009; 5: 419-426.
    • (2009) Nat Rev Neurol , vol.5 , pp. 419-426
    • Purow, B.1    Schiff, D.2
  • 5
    • 0036939214 scopus 로고    scopus 로고
    • Ionizing radiation and cancer risk: Evidence from epidemiology
    • discussion 42-4
    • Ron E. Ionizing radiation and cancer risk: evidence from epidemiology. Pediatr Radiol 2002; 32: 232-237 discussion 42-4.
    • (2002) Pediatr Radiol , vol.32 , pp. 232-237
    • Ron, E.1
  • 7
    • 0038012731 scopus 로고    scopus 로고
    • Radiation-induced gliomas: Report of 10 cases and review of the literature
    • discussion 7
    • Salvati M, Frati A, Russo N, Caroli E, Polli FM, Minniti G et al. Radiation-induced gliomas: report of 10 cases and review of the literature. Surg Neurol 2003; 60: 60-67, discussion 7.
    • (2003) Surg Neurol , vol.60 , pp. 60-67
    • Salvati, M.1    Frati, A.2    Russo, N.3    Caroli, E.4    Polli, F.M.5    Minniti, G.6
  • 8
    • 55549115678 scopus 로고    scopus 로고
    • Radiation dose to the brain and subsequent risk of developing brain tumors in pediatric patients undergoing interventional neuroradiology procedures
    • Thierry-Chef I, Simon SL, Land CE, Miller DL. Radiation dose to the brain and subsequent risk of developing brain tumors in pediatric patients undergoing interventional neuroradiology procedures. Radiat Res 2008; 170: 553-565.
    • (2008) Radiat Res , vol.170 , pp. 553-565
    • Thierry-Chef, I.1    Simon, S.L.2    Land, C.E.3    Miller, D.L.4
  • 10
    • 84864776903 scopus 로고    scopus 로고
    • Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: A retrospective cohort study
    • Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP et al. Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study. Lancet 2012; 380: 499-505.
    • (2012) Lancet , vol.380 , pp. 499-505
    • Pearce, M.S.1    Salotti, J.A.2    Little, M.P.3    McHugh, K.4    Lee, C.5    Kim, K.P.6
  • 11
    • 44349143334 scopus 로고    scopus 로고
    • Heavy ion carcinogenesis and human space exploration
    • Durante M, Cucinotta FA. Heavy ion carcinogenesis and human space exploration. Nat Rev Cancer 2008; 8: 465-472.
    • (2008) Nat Rev Cancer , vol.8 , pp. 465-472
    • Durante, M.1    Cucinotta, F.A.2
  • 12
    • 84155163991 scopus 로고    scopus 로고
    • Repair of DNA damage induced by accelerated heavy ions-a mini review
    • Okayasu R. Repair of DNA damage induced by accelerated heavy ions-a mini review. Int J Cancer 2012; 130: 991-1000.
    • (2012) Int J Cancer , vol.130 , pp. 991-1000
    • Okayasu, R.1
  • 13
    • 79956225907 scopus 로고    scopus 로고
    • Clustered DNA lesion repair in eukaryotes: Relevance to mutagenesis and cell survival
    • Sage E, Harrison L. Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival. Mutat Res 2011; 711: 123-133.
    • (2011) Mutat Res , vol.711 , pp. 123-133
    • Sage, E.1    Harrison, L.2
  • 14
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: Signaling, repair and the cancer connection
    • Khanna KK, Jackson SP. DNA double-strand breaks: signaling, repair and the cancer connection. Nat Genet 2001; 27: 247-254.
    • (2001) Nat Genet , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 15
    • 77957763073 scopus 로고    scopus 로고
    • Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA doublestrand breaks
    • Camacho CV, Mukherjee B, McEllin B, Ding LH, Hu B, Habib AA et al. Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA doublestrand breaks. Carcinogenesis 2010; 31: 1889-1896.
    • (2010) Carcinogenesis , vol.31 , pp. 1889-1896
    • Camacho, C.V.1    Mukherjee, B.2    McEllin, B.3    Ding, L.H.4    Hu, B.5    Habib, A.A.6
  • 16
    • 66249149058 scopus 로고    scopus 로고
    • EGFRvIII and DNA double-strand break repair: A molecular mechanism for radioresistance in glioblastoma
    • Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S et al. EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Res 2009; 69: 4252-4259.
    • (2009) Cancer Res , vol.69 , pp. 4252-4259
    • Mukherjee, B.1    McEllin, B.2    Camacho, C.V.3    Tomimatsu, N.4    Sirasanagandala, S.5    Nannepaga, S.6
  • 17
    • 35848934352 scopus 로고    scopus 로고
    • Neural stem cells tumour stem cells and brain tumours: Dangerous relationships
    • Sutter R, Yadirgi G, Marino S. Neural stem cells, tumour stem cells and brain tumours: dangerous relationships Biochim Biophys Acta 2007; 1776: 125-137.
    • (2007) Biochim Biophys Acta , vol.1776 , pp. 125-137
    • Sutter, R.1    Yadirgi, G.2    Marino, S.3
  • 18
    • 79957927593 scopus 로고    scopus 로고
    • Genetic modeling of gliomas in mice: New tools to tackle old problems
    • Hambardzumyan D, Parada LF, Holland EC, Charest A. Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia 2011; 59: 1155-1168.
    • (2011) Glia , vol.59 , pp. 1155-1168
    • Hambardzumyan, D.1    Parada, L.F.2    Holland, E.C.3    Charest, A.4
  • 20
    • 38049100456 scopus 로고    scopus 로고
    • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
    • Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci USA 2007; 104: 20007-20012.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20007-20012
    • Beroukhim, R.1    Getz, G.2    Nghiemphu, L.3    Barretina, J.4    Hsueh, T.5    Linhart, D.6
  • 23
    • 33645740288 scopus 로고    scopus 로고
    • Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis
    • Smolen GA, Muir B, Mohapatra G, Barmettler A, Kim WJ, Rivera MN et al. Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis. Cancer Res 2006; 66: 3452-3455.
    • (2006) Cancer Res , vol.66 , pp. 3452-3455
    • Smolen, G.A.1    Muir, B.2    Mohapatra, G.3    Barmettler, A.4    Kim, W.J.5    Rivera, M.N.6
  • 24
    • 0025686126 scopus 로고
    • Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts
    • Bigner SH, Humphrey PA, Wong AJ, Vogelstein B, Mark J, Friedman HS et al. Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res 1990; 50: 8017-8022.
    • (1990) Cancer Res , vol.50 , pp. 8017-8022
    • Bigner, S.H.1    Humphrey, P.A.2    Wong, A.J.3    Vogelstein, B.4    Mark, J.5    Friedman, H.S.6
  • 25
    • 79959971880 scopus 로고    scopus 로고
    • C-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
    • Li Y, Li A, Glas M, Lal B, Ying M, Sang Y et al. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc Natl Acad Sci USA. 2011; 108: 9951-9956.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , pp. 9951-9956
    • Li, Y.1    Li, A.2    Glas, M.3    Lal, B.4    Ying, M.5    Sang, Y.6
  • 26
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis M, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
    • McLendon, R.1    Friedman, A.2    Bigner, D.3    Van Meir, E.G.4    Brat, D.J.5    Mastrogianakis, M.6
  • 29
    • 33646446295 scopus 로고    scopus 로고
    • Imaging features that discriminate between foci induced by high-and low-LET radiation in human fibroblasts
    • Costes SV, Boissiere A, Ravani S, Romano R, Parvin B, Barcellos-Hoff MH. Imaging features that discriminate between foci induced by high-and low-LET radiation in human fibroblasts. Radiat Res 2006; 165: 505-515.
    • (2006) Radiat Res , vol.165 , pp. 505-515
    • Costes, S.V.1    Boissiere, A.2    Ravani, S.3    Romano, R.4    Parvin, B.5    Barcellos-Hoff, M.H.6
  • 30
    • 84888130375 scopus 로고    scopus 로고
    • Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation
    • Saha J, Wang M, Cucinotta FA. Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation. DNA Repair (Amst) 2013; 12: 1143-1151.
    • (2013) DNA Repair (Amst) , vol.12 , pp. 1143-1151
    • Saha, J.1    Wang, M.2    Cucinotta, F.A.3
  • 31
    • 42249098075 scopus 로고    scopus 로고
    • The Ku-dependent non-homologous endjoining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation
    • Wang H, Wang X, Zhang P, Wang Y. The Ku-dependent non-homologous endjoining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation. DNA Repair (Amst) 2008; 7: 725-733.
    • (2008) DNA Repair (Amst) , vol.7 , pp. 725-733
    • Wang, H.1    Wang, X.2    Zhang, P.3    Wang, Y.4
  • 34
    • 78649420006 scopus 로고    scopus 로고
    • MET signalling: Principles and functions in development, organ regeneration and cancer
    • Trusolino L, Bertotti A, Comoglio PM. MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol 2010; 11: 834-848.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 834-848
    • Trusolino, L.1    Bertotti, A.2    Comoglio, P.M.3
  • 36
  • 39
    • 27144524893 scopus 로고    scopus 로고
    • The scatter factor/hepatocyte growth factor: C-met pathway in human embryonal central nervous system tumor malignancy
    • Li Y, Lal B, Kwon S, Fan X, Saldanha U, Reznik TE et al. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy. Cancer Res 2005; 65: 9355-9362.
    • (2005) Cancer Res , vol.65 , pp. 9355-9362
    • Li, Y.1    Lal, B.2    Kwon, S.3    Fan, X.4    Saldanha, U.5    Reznik, T.E.6
  • 40
    • 0031587985 scopus 로고    scopus 로고
    • Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth
    • Laterra J, Rosen E, Nam M, Ranganathan S, Fielding K, Johnston P. Scatter factor/hepatocyte growth factor expression enhances human glioblastoma tumorigenicity and growth. Biochem Biophys Res Commun 1997; 235: 743-747.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 743-747
    • Laterra, J.1    Rosen, E.2    Nam, M.3    Ranganathan, S.4    Fielding, K.5    Johnston, P.6
  • 41
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 2007; 316: 1039-1043.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3    Song, Y.4    Hyland, C.5    Park, J.O.6
  • 42
    • 84862657056 scopus 로고    scopus 로고
    • Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme
    • Jun HJ, Acquaviva J, Chi D, Lessard J, Zhu H, Woolfenden S et al. Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme. Oncogene 2012; 31: 3039-3050.
    • (2012) Oncogene , vol.31 , pp. 3039-3050
    • Jun, H.J.1    Acquaviva, J.2    Chi, D.3    Lessard, J.4    Zhu, H.5    Woolfenden, S.6
  • 44
    • 35348822482 scopus 로고    scopus 로고
    • Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
    • Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 2007; 318: 287-290.
    • (2007) Science , vol.318 , pp. 287-290
    • Stommel, J.M.1    Kimmelman, A.C.2    Ying, H.3    Nabioullin, R.4    Ponugoti, A.H.5    Wiedemeyer, R.6
  • 45
    • 79955420135 scopus 로고    scopus 로고
    • Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
    • De Bacco F, Luraghi P, Medico E, Reato G, Girolami F, Perera T et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. J Natl Cancer Inst 2011; 103: 645-661.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 645-661
    • De Bacco, F.1    Luraghi, P.2    Medico, E.3    Reato, G.4    Girolami, F.5    Perera, T.6
  • 46
    • 78650179903 scopus 로고    scopus 로고
    • C-Met expression is associated with time to recurrence in patients with glioblastoma multiforme
    • Liu W, Fu Y, Xu S, Ding F, Zhao G, Zhang K et al. c-Met expression is associated with time to recurrence in patients with glioblastoma multiforme. J Clin Neurosci 2011; 18: 119-121.
    • (2011) J Clin Neurosci , vol.18 , pp. 119-121
    • Liu, W.1    Fu, Y.2    Xu, S.3    Ding, F.4    Zhao, G.5    Zhang, K.6
  • 48
    • 0035817687 scopus 로고    scopus 로고
    • Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
    • Krimpenfort P, Quon KC, Mooi WJ, Loonstra A, Berns A. Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice. Nature 2001; 413: 83-86.
    • (2001) Nature , vol.413 , pp. 83-86
    • Krimpenfort, P.1    Quon, K.C.2    Mooi, W.J.3    Loonstra, A.4    Berns, A.5
  • 50
    • 49149090064 scopus 로고    scopus 로고
    • Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha
    • Scotto L, Narayan G, Nandula SV, Subramaniyam S, Kaufmann AM, Wright JD et al. Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha. Mol Cancer 2008; 7: 58.
    • (2008) Mol Cancer , vol.7 , pp. 58
    • Scotto, L.1    Narayan, G.2    Nandula, S.V.3    Subramaniyam, S.4    Kaufmann, A.M.5    Wright, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.