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Volumn 46, Issue 3, 2014, Pages 287-293

Identification of functional cooperative mutations of SETD2 in human acute leukemia

(38)  Zhu, Xiaofan a   He, Fuhong b   Zeng, Huimin a   Ling, Shaoping b   Chen, Aili b,d   Wang, Yaqin a   Yan, Xiaomei c   Wei, Wei a   Pang, Yakun a   Cheng, Hui a   Hua, Chunlan a   Zhang, Yue a,c   Yang, Xuejing b,d   Lu, Xin b,d   Cao, Lihua b   Hao, Lingtong b   Dong, Lili b   Zou, Wei b   Wu, Jun b   Li, Xia b,d   more..


Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; NUCLEOPHOSMIN; TRANSCRIPTION FACTOR RUNX1;

EID: 84895885401     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2894     Document Type: Article
Times cited : (208)

References (63)
  • 1
    • 35548934558 scopus 로고    scopus 로고
    • Mll translocations, histone modifications and leukaemia stem-cell development
    • Krivtsov, A.V. & Armstrong, S.A. MLL translocations, histone modifications and leukaemia stem-cell development. Nat. Rev. Cancer 7, 823-833 (2007
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 2
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N. Engl. J. Med. 368, 2059-2074 (2013
    • (2013) N. Engl. J. Med , vol.368 , pp. 2059-2074
  • 3
    • 67650736251 scopus 로고    scopus 로고
    • Nrip3: A novel translocation partner of mll detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements
    • Balgobind, B.V. et al. NRIP3: A novel translocation partner of MLL detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements. Haematologica 94, 1033 (2009
    • (2009) Haematologica , vol.94 , pp. 1033
    • Balgobind, B.V.1
  • 4
    • 27444436367 scopus 로고    scopus 로고
    • Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase
    • Sun, X.J. et al. Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. J. Biol. Chem. 280, 35261-35271 (2005
    • (2005) J. Biol. Chem , vol.280 , pp. 35261-35271
    • Sun, X.J.1
  • 5
    • 33747873409 scopus 로고    scopus 로고
    • Chromatin structural elements and chromosomal translocations in leukemia
    • Zhang, Y. & Rowley, J.D. Chromatin structural elements and chromosomal translocations in leukemia. DNA Repair (Amst.) 5, 1282-1297 (2006
    • (2006) DNA Repair (Amst , vol.5 , pp. 1282-1297
    • Zhang, Y.1    Rowley, J.D.2
  • 6
    • 77955875047 scopus 로고    scopus 로고
    • The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers
    • Zhang, Y. et al. The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv. Immunol. 106, 93-133 (2010
    • (2010) Adv. Immunol , vol.106 , pp. 93-133
    • Zhang, Y.1
  • 7
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman, F., Johansson, B. & Mertens, F. The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer 7, 233-245 (2007
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 9
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves, M.F. & Wiemels, J. Origins of chromosome translocations in childhood leukaemia. Nat. Rev. Cancer 3, 639-649 (2003
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 10
    • 38549139593 scopus 로고    scopus 로고
    • Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
    • Edmunds, J.W., Mahadevan, L.C. & Clayton, A.L. Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation. EMBO J. 27, 406-420 (2008
    • (2008) EMBO J. , vol.27 , pp. 406-420
    • Edmunds, J.W.1    Mahadevan, L.C.2    Clayton, A.L.3
  • 11
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger, S.L. The complex language of chromatin regulation during transcription. Nature 447, 407-412 (2007
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 12
    • 80053513386 scopus 로고    scopus 로고
    • Remarkable difference of somatic mutation patterns between oncogenes and tumor suppressor genes
    • Liu, H., Xing, Y., Yang, S. & Tian, D. Remarkable difference of somatic mutation patterns between oncogenes and tumor suppressor genes. Oncol. Rep. 26, 1539-1546 (2011
    • (2011) Oncol. Rep , vol.26 , pp. 1539-1546
    • Liu, H.1    Xing, Y.2    Yang, S.3    Tian, D.4
  • 13
    • 77957334627 scopus 로고    scopus 로고
    • Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
    • Mayshar, Y. et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 7, 521-531 (2010
    • (2010) Cell Stem Cell , vol.7 , pp. 521-531
    • Mayshar, Y.1
  • 14
    • 79961138790 scopus 로고    scopus 로고
    • Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells
    • Ben-David, U., Mayshar, Y. & Benvenisty, N. Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells. Cell Stem Cell 9, 97-102 (2011
    • (2011) Cell Stem Cell , vol.9 , pp. 97-102
    • Ben-David, U.1    Mayshar, Y.2    Benvenisty, N.3
  • 15
    • 84855393367 scopus 로고    scopus 로고
    • Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets
    • Dondeti, V.R. et al. Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets. Cancer Res. 72, 112-121 (2012
    • (2012) Cancer Res , vol.72 , pp. 112-121
    • Dondeti, V.R.1
  • 16
    • 84879890360 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of clear cell renal cell carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499, 43-49 (2013
    • (2013) Nature , vol.499 , pp. 43-49
  • 17
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
    • Rhodes, D.R. et al. Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia 9, 166-180 (2007
    • (2007) Neoplasia , vol.9 , pp. 166-180
    • Rhodes, D.R.1
  • 18
    • 29144448731 scopus 로고    scopus 로고
    • Solution structure of the set2-rpb1 interacting domain of human set2 and its interaction with the hyperphosphorylated c-Terminal domain of rpb1
    • Li, M. et al. Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-Terminal domain of Rpb1. Proc. Natl. Acad. Sci. USA 102, 17636-17641 (2005
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17636-17641
    • Li, M.1
  • 19
    • 77953170322 scopus 로고    scopus 로고
    • Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma
    • Duns, G. et al. Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma. Cancer Res. 70, 4287-4291 (2010
    • (2010) Cancer Res , vol.70 , pp. 4287-4291
    • Duns, G.1
  • 20
    • 84886712846 scopus 로고    scopus 로고
    • Mutations in setd2 and genes affecting histone h3k36 methylation target hemispheric high-grade gliomas
    • Fontebasso, A.M. et al. Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas. Acta Neuropathol. 125, 659-669 (2013
    • (2013) Acta Neuropathol , vol.125 , pp. 659-669
    • Fontebasso, A.M.1
  • 21
    • 71749121612 scopus 로고    scopus 로고
    • Regulating the leukaemia stem cell
    • Cleary, M.L. Regulating the leukaemia stem cell. Best Pract. Res. Clin. Haematol. 22, 483-487 (2009
    • (2009) Best Pract. Res. Clin. Haematol , vol.22 , pp. 483-487
    • Cleary, M.L.1
  • 22
    • 15844394270 scopus 로고    scopus 로고
    • An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
    • Corral, J. et al. An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes. Cell 85, 853-861 (1996
    • (1996) Cell , vol.85 , pp. 853-861
    • Corral, J.1
  • 23
    • 33749424957 scopus 로고    scopus 로고
    • Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
    • Dorrance, A.M. et al. Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J. Clin. Invest. 116, 2707-2716 (2006
    • (2006) J. Clin. Invest , vol.116 , pp. 2707-2716
    • Dorrance, A.M.1
  • 24
    • 0036463950 scopus 로고    scopus 로고
    • Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia
    • Higuchi, M. et al. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. Cancer Cell 1, 63-74 (2002
    • (2002) Cancer Cell , vol.1 , pp. 63-74
    • Higuchi, M.1
  • 25
    • 84864565435 scopus 로고    scopus 로고
    • Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias
    • Zorko, N.A. et al. Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias. Blood 120, 1130-1136 (2012
    • (2012) Blood , vol.120 , pp. 1130-1136
    • Zorko, N.A.1
  • 26
    • 0042924440 scopus 로고    scopus 로고
    • An activated receptor tyrosine kinase, tel/pdgfβr, cooperates with aml1/eto to induce acute myeloid leukemia in mice
    • Grisolano, J.L., O'Neal, J., Cain, J. & Tomasson, M.H. An activated receptor tyrosine kinase, TEL/PDGFβR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice. Proc. Natl. Acad. Sci. USA 100, 9506-9511 (2003
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9506-9511
    • Grisolano, J.L.1    O'Neal, J.2    Cain, J.3    Tomasson, M.H.4
  • 27
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 28
    • 33751216490 scopus 로고    scopus 로고
    • Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells
    • Gal, H. et al. Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells. Leukemia 20, 2147-2154 (2006
    • (2006) Leukemia , vol.20 , pp. 2147-2154
    • Gal, H.1
  • 29
    • 41449118521 scopus 로고    scopus 로고
    • Module map of stem cell genes guides creation of epithelial cancer stem cells
    • Wong, D.J. et al. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2, 333-344 (2008
    • (2008) Cell Stem Cell , vol.2 , pp. 333-344
    • Wong, D.J.1
  • 30
    • 41449087009 scopus 로고    scopus 로고
    • Cancer: Inappropriate expression of stem cell programs
    • Wang, Y. & Armstrong, S.A. Cancer: Inappropriate expression of stem cell programs? Cell Stem Cell 2, 297-299 (2008
    • (2008) Cell Stem Cell , vol.2 , pp. 297-299
    • Wang, Y.1    Armstrong, S.A.2
  • 31
    • 77950287628 scopus 로고    scopus 로고
    • The wnt/β-catenin pathway is required for the development of leukemia stem cells in aml
    • Wang, Y. et al. The Wnt/β-catenin pathway is required for the development of leukemia stem cells in AML. Science 327, 1650-1653 (2010
    • (2010) Science , vol.327 , pp. 1650-1653
    • Wang, Y.1
  • 32
    • 84858983547 scopus 로고    scopus 로고
    • Kegg for integration and interpretation of large-scale molecular data sets
    • Kanehisa, M., Goto, S., Sato, Y., Furumichi, M. & Tanabe, M. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 40, D109-D114 (2012
    • (2012) Nucleic Acids Res , vol.40
    • Kanehisa, M.1    Goto, S.2    Sato, Y.3    Furumichi, M.4    Tanabe, M.5
  • 33
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger, M. et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366, 883-892 (2012
    • (2012) N. Engl. J. Med , vol.366 , pp. 883-892
    • Gerlinger, M.1
  • 34
    • 80052266351 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
    • Gui, Y. et al. Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat. Genet. 43, 875-878 (2011
    • (2011) Nat. Genet , vol.43 , pp. 875-878
    • Gui, Y.1
  • 35
    • 79251635938 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of the swi/snf complex gene pbrm1 in renal carcinoma
    • Varela, I. et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469, 539-542 (2011
    • (2011) Nature , vol.469 , pp. 539-542
    • Varela, I.1
  • 36
    • 75149188170 scopus 로고    scopus 로고
    • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
    • Dalgliesh, G.L. et al. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 463, 360-363 (2010
    • (2010) Nature , vol.463 , pp. 360-363
    • Dalgliesh, G.L.1
  • 37
    • 84860327480 scopus 로고    scopus 로고
    • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
    • Zang, Z.J. et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat. Genet. 44, 570-574 (2012
    • (2012) Nat. Genet , vol.44 , pp. 570-574
    • Zang, Z.J.1
  • 38
    • 84862976633 scopus 로고    scopus 로고
    • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
    • Fujimoto, A. et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat. Genet. 44, 760-764 (2012
    • (2012) Nat. Genet , vol.44 , pp. 760-764
    • Fujimoto, A.1
  • 39
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
    • Zhang, J. et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature 481, 157-163 (2012
    • (2012) Nature , vol.481 , pp. 157-163
    • Zhang, J.1
  • 40
    • 84862635654 scopus 로고    scopus 로고
    • Molecular biology genetic events that shape the cancer epigenome
    • Ryan, R.J. & Bernstein, B.E. Molecular biology. Genetic events that shape the cancer epigenome. Science 336, 1513-1514 (2012
    • (2012) Science , vol.336 , pp. 1513-1514
    • Ryan, R.J.1    Bernstein, B.E.2
  • 41
    • 69649109364 scopus 로고    scopus 로고
    • Circos: An information aesthetic for comparative genomics
    • Krzywinski, M. et al. Circos: An information aesthetic for comparative genomics. Genome Res. 19, 1639-1645 (2009
    • (2009) Genome Res , vol.19 , pp. 1639-1645
    • Krzywinski, M.1
  • 42
  • 43
  • 44
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with burrows-wheeler transform
    • Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 45
    • 68549104404 scopus 로고    scopus 로고
    • The sequence alignment/map format and samtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 46
    • 64849083125 scopus 로고    scopus 로고
    • Cnv-seq a new method to detect copy number variation using high-Throughput sequencing
    • Xie, C. & Tammi, M.T. CNV-seq, a new method to detect copy number variation using high-Throughput sequencing. BMC Bioinformatics 10, 80 (2009
    • (2009) BMC Bioinformatics , vol.10 , pp. 80
    • Xie, C.1    Tammi, M.T.2
  • 47
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based dna copy number data
    • Olshen, A.B., Venkatraman, E.S., Lucito, R. & Wigler, M. Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 5, 557-572 (2004
    • (2004) Biostatistics , vol.5 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 48
    • 0035173378 scopus 로고    scopus 로고
    • Dbsnp: The ncbi database of genetic variation
    • Sherry, S.T. et al. dbSNP: The NCBI database of genetic variation. Nucleic Acids Res. 29, 308-311 (2001
    • (2001) Nucleic Acids Res , vol.29 , pp. 308-311
    • Sherry, S.T.1
  • 49
    • 69749124820 scopus 로고    scopus 로고
    • The first Korean genome sequence and analysis: Full genome sequencing for a socio-ethnic group
    • Ahn, S.M. et al. The first Korean genome sequence and analysis: Full genome sequencing for a socio-ethnic group. Genome Res. 19, 1622-1629 (2009
    • (2009) Genome Res , vol.19 , pp. 1622-1629
    • Ahn, S.M.1
  • 50
    • 58149194602 scopus 로고    scopus 로고
    • The yh database: The first asian diploid genome database
    • Li, G. et al. The YH database: The first Asian diploid genome database. Nucleic Acids Res. 37, D1025-D1028 (2009
    • (2009) Nucleic Acids Res , vol.37
    • Li, G.1
  • 51
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • Abecasis, G.R. et al. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Abecasis, G.R.1
  • 52
    • 78650315158 scopus 로고    scopus 로고
    • Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion
    • Mosca, L. et al. Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion. Clin. Cancer Res. 16, 5641-5653 (2010
    • (2010) Clin. Cancer Res , vol.16 , pp. 5641-5653
    • Mosca, L.1
  • 53
    • 33646241534 scopus 로고    scopus 로고
    • High-Throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers
    • Tai, A.L. et al. High-Throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers. Cancer Res. 66, 4133-4138 (2006
    • (2006) Cancer Res , vol.66 , pp. 4133-4138
    • Tai, A.L.1
  • 54
    • 34249781123 scopus 로고    scopus 로고
    • Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma
    • Onken, M.D. et al. Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma. Clin. Cancer Res. 13, 2923-2927 (2007
    • (2007) Clin. Cancer Res , vol.13 , pp. 2923-2927
    • Onken, M.D.1
  • 55
    • 35748935572 scopus 로고    scopus 로고
    • Molecular analysis of deletions in human chromosome 3p21 and the role of resident cancer genes in disease
    • Angeloni, D. Molecular analysis of deletions in human chromosome 3p21 and the role of resident cancer genes in disease. Brief. Funct. Genomic. Proteomic. 6, 19-39 (2007
    • (2007) Brief. Funct. Genomic. Proteomic , vol.6 , pp. 19-39
    • Angeloni, D.1
  • 56
    • 78651071913 scopus 로고    scopus 로고
    • Detection of kras and braf mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-pcr sequencing and broad-spectrum mass spectrometry genotyping
    • Arcila, M., Lau, C., Nafa, K. & Ladanyi, M. Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping. J. Mol. Diagn. 13, 64-73 (2011
    • (2011) J. Mol. Diagn , vol.13 , pp. 64-73
    • Arcila, M.1    Lau, C.2    Nafa, K.3    Ladanyi, M.4
  • 57
    • 84877343113 scopus 로고    scopus 로고
    • Aberrant promoter hypermethylation of pbrm1, bap1, setd2, kdm6a and other chromatin-modifying genes is absent or rare in clear cell rcc
    • Ibragimova, I., Maradeo, M.E., Dulaimi, E. & Cairns, P. Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC. Epigenetics 8, 486-493 (2013
    • (2013) Epigenetics , vol.8 , pp. 486-493
    • Ibragimova, I.1    Maradeo, M.E.2    Dulaimi, E.3    Cairns, P.4
  • 58
    • 73649110641 scopus 로고    scopus 로고
    • Dna methylation signatures identify biologically distinct subtypes in acute myeloid leukemia
    • Figueroa, M.E. et al. DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell 17, 13-27 (2010
    • (2010) Cancer Cell , vol.17 , pp. 13-27
    • Figueroa, M.E.1
  • 59
    • 84866078903 scopus 로고    scopus 로고
    • Aberration of p73 promoter methylation in de novo myelodysplastic syndrome
    • Zhao, Y. et al. Aberration of p73 promoter methylation in de novo myelodysplastic syndrome. Hematology 17, 275-282 (2012
    • (2012) Hematology , vol.17 , pp. 275-282
    • Zhao, Y.1
  • 60
    • 84863229585 scopus 로고    scopus 로고
    • A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
    • Wang, J. et al. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell 148, 1001-1014 (2012
    • (2012) Cell , vol.148 , pp. 1001-1014
    • Wang, J.1
  • 61
    • 84864548794 scopus 로고    scopus 로고
    • Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells
    • Zhang, Y. et al. Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells. Blood 120, 1118-1129 (2012
    • (2012) Blood , vol.120 , pp. 1118-1129
    • Zhang, Y.1
  • 62
    • 84859885816 scopus 로고    scopus 로고
    • Differential gene and transcript expression analysis of rna-seq experiments with tophat and cufflinks
    • Trapnell, C. et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat. Protoc. 7, 562-578 (2012
    • (2012) Nat. Protoc , vol.7 , pp. 562-578
    • Trapnell, C.1
  • 63
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using david bioinformatics resources
    • Huang, W., Sherman, B.T. & Lempicki, R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57 (2009.
    • (2009) Nat. Protoc , vol.4 , pp. 44-57
    • Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.