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Volumn 17, Issue 5, 2012, Pages 275-282

Aberration of p73 promoter methylation in de novo myelodysplastic syndrome

Author keywords

Decitabine; Hypermethylation; Myelodysplastic syndrome; p73

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE;

EID: 84866078903     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/1607845412Y.0000000018     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 0037298128 scopus 로고    scopus 로고
    • The myelodysplastic syndrome (s): A perspective and review highlighting current controversies
    • Steensma DP, Tefferi A. The myelodysplastic syndrome (s): a perspective and review highlighting current controversies. Leuk Res. 2003;27:95-120.
    • (2003) Leuk Res , vol.27 , pp. 95-120
    • Steensma, D.P.1    Tefferi, A.2
  • 3
    • 35448934364 scopus 로고    scopus 로고
    • Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome
    • Kerbauy DB, Deeg HJ. Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Exp Hematol. 2007;35:1739-1746.
    • (2007) Exp Hematol , vol.35 , pp. 1739-1746
    • Kerbauy, D.B.1    Deeg, H.J.2
  • 4
    • 34250213859 scopus 로고    scopus 로고
    • DNA methylation as a therapeutic target in cancer
    • Issa JPJ. DNA methylation as a therapeutic target in cancer. Clin Cancer Res. 2007;13:1634-1637.
    • (2007) Clin Cancer Res , vol.13 , pp. 1634-1637
    • Issa, J.P.J.1
  • 5
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med. 2003;349:2042-2054.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 6
    • 60849089645 scopus 로고    scopus 로고
    • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
    • Jiang Y, Dunbar A, Gondek LP, Mohan S, Rataul M, O'Keefe C, et al Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 2009;113:1315-1325.
    • (2009) Blood , vol.113 , pp. 1315-1325
    • Jiang, Y.1    Dunbar, A.2    Gondek, L.P.3    Mohan, S.4    Rataul, M.5    O'Keefe, C.6    et al7
  • 7
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, et al Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997;90:809-819.
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang, A.3    Creancier, L.4    Biscan, J.C.5    Valent, A.6    et al7
  • 10
    • 0033565514 scopus 로고    scopus 로고
    • Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associ- ated with 5′ CpG island methylation
    • Corn GP, Kuerbitz SJ, van Noesel MM, Esteller M, Compitello N, Baylin SB, et al Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associ- ated with 5′ CpG island methylation. Cancer Res. 1999;59:3352.
    • (1999) Cancer Res , vol.59 , pp. 3352
    • Corn, G.P.1    Kuerbitz, S.J.2    van Noesel, M.M.3    Esteller, M.4    Compitello, N.5    Baylin, S.B.6
  • 11
    • 0036837257 scopus 로고    scopus 로고
    • Frequent inactivation of the p73 gene by abnormal methylation or LOH in non-Hodgkin's lymphomas
    • Martinez-Delgado B, Melendez B, Cuadros M, Jose Garcia M, Nomdedeu J, Rivas C, et al Frequent inactivation of the p73 gene by abnormal methylation or LOH in non-Hodgkin's lymphomas. Int J Cancer. 2002;102:15-9.
    • (2002) Int J Cancer , vol.102 , pp. 15-19
    • Martinez-Delgado, B.1    Melendez, B.2    Cuadros, M.3    Jose, G.M.4    Nomdedeu, J.5    Rivas, C.6
  • 12
    • 18044381319 scopus 로고    scopus 로고
    • Retracted: Alteration of p73 in acute myelogenous leukemia
    • Sahu GR, Mishra R, Nagpal JK, Das BR. Retracted: alteration of p73 in acute myelogenous leukemia. Am J Hematol. 2005;79:1-7.
    • (2005) Am J Hematol , vol.79 , pp. 1-7
    • Sahu, G.R.1    Mishra, R.2    Nagpal, J.K.3    Das, B.R.4
  • 13
    • 7244237957 scopus 로고    scopus 로고
    • Aberrant methylation of multiple tumor suppressor genes in acute myeloid leukemia
    • Ekmekci CG, Gutiérrez MI, Siraj AK, Ozbek U, Bhatia K. Aberrant methylation of multiple tumor suppressor genes in acute myeloid leukemia. Am J Hematol. 2004;77:233-240.
    • (2004) Am J Hematol , vol.77 , pp. 233-240
    • Ekmekci, C.G.1    Gutiérrez, M.I.2    Siraj, A.K.3    Ozbek, U.4    Bhatia, K.5
  • 15
    • 29144500326 scopus 로고    scopus 로고
    • Decitabine activates specific caspases downstream of p73 in myeloid leukemia
    • Tamm I, Wagner M, Schmelz K. Decitabine activates specific caspases downstream of p73 in myeloid leukemia. Ann Hematol. 2005;84:47-53.
    • (2005) Ann Hematol , vol.84 , pp. 47-53
    • Tamm, I.1    Wagner, M.2    Schmelz, K.3
  • 16
    • 4944236206 scopus 로고    scopus 로고
    • Promoter hypermethylation of cancer-related genes: A strong independent prognostic factor in acute lymphoblastic leukemia
    • Roman-Gomez J, Jimenez-Velasco A, Castillejo JA, Agirre X, Barrios M, Navarro G, et al Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia. Blood 2004;104:2492-2498.
    • (2004) Blood , vol.104 , pp. 2492-2498
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Castillejo, J.A.3    Agirre, X.4    Barrios, M.5    Navarro, G.6
  • 18
    • 27244438584 scopus 로고    scopus 로고
    • Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis
    • Roman-Gomez J, Jimenez-Velasco A, Agirre X, Prosper F, Heiniger A, Torres A. Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis. J Clin Oncol. 2005;23:7043-70439.
    • (2005) J Clin Oncol , vol.23 , pp. 7043-70439
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3    Prosper, F.4    Heiniger, A.5    Torres, A.6
  • 19
    • 0036141154 scopus 로고    scopus 로고
    • Specific patterns of gene methylation in natural killer cell lymphomas: P73 is consistently involved
    • Siu LLP, Chan JKC, Wong KF, Kwong YL. Specific patterns of gene methylation in natural killer cell lymphomas: p73 is consistently involved. Am J Pathol. 2002;160:59.
    • (2002) Am J Pathol , vol.160 , pp. 59
    • Siu, L.L.P.1    Chan, J.K.C.2    Wong, K.F.3    Kwong, Y.L.4
  • 21
    • 34249786233 scopus 로고    scopus 로고
    • Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference
    • Valent P, Horny HP, Bennett JM, Fonatsch C, Germing U, Greenberg P, et al Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference. Leuk Res. 2007;31:727-736.
    • (2007) Leuk Res , vol.31 , pp. 727-736
    • Valent, P.1    Horny, H.P.2    Bennett, J.M.3    Fonatsch, C.4    Germing, U.5    Greenberg, P.6    et al7
  • 22
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 2002;100:2292-2302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 23
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • Greenberg P, Cox C, LeBeau MM, Fenaux P, Morel P, Sanz G, et al International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89:2079.
    • (2079) Blood , vol.1997 , pp. 89
    • Greenberg, P.1    Cox, C.2    Lebeau, M.M.3    Fenaux, P.4    Morel, P.5    Sanz, G.6    et al7
  • 24
    • 33745968917 scopus 로고    scopus 로고
    • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
    • Cheson BD, Greenberg PL, Bennett JM, Lowenberg B, Wijermans PW, Nimer SD, et al Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006;108:419.
    • (2006) Blood , vol.108 , pp. 419
    • Cheson, B.D.1    Greenberg, P.L.2    Bennett, J.M.3    Lowenberg, B.4    Wijermans, P.W.5    Nimer, S.D.6
  • 25
    • 33644859241 scopus 로고    scopus 로고
    • ΔTAp73 upregulation correlates with poor prognosis in human tumors: Putative in vivo network involving p73 isoforms, p53, and E2F-1
    • Domínguez G, García JM, Peña C, Silva J, García V, Martínez L, et al ΔTAp73 upregulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53, and E2F-1. J Clin Oncol. 2006;24:805.
    • (2006) J Clin Oncol , vol.24 , pp. 805
    • Domínguez, G.1    García, J.M.2    Peña, C.3    Silva, J.4    García, V.5    Martínez, L.6    et al7
  • 26
    • 84855917467 scopus 로고    scopus 로고
    • The roles of SDF-1/CXCR4 axis and its relationship with apoptosis in the myelodysplastic syndromes
    • Chunkang C, Rui Y, Feng X, Juan G, Xi Z, Lingyun W, et al The roles of SDF-1/CXCR4 axis and its relationship with apoptosis in the myelodysplastic syndromes. Med Oncol. 2010:28 Suppl 1:1-7.
    • Med Oncol , vol.1 , Issue.1 SUPPL. , pp. 1-7
    • Chunkang, C.1    Rui, Y.2    Feng, X.3    Juan, G.4    Xi, Z.5    Lingyun, W.6
  • 27
    • 0141502199 scopus 로고    scopus 로고
    • Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
    • Christiansen D, Andersen M, Pedersen-Bjergaard J. Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 2003;17:1813-1819.
    • (2003) Leukemia , vol.17 , pp. 1813-1819
    • Christiansen, D.1    Andersen, M.2    Pedersen-Bjergaard, J.3
  • 28
    • 33644878393 scopus 로고    scopus 로고
    • Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients
    • Aggerholm A, Holm MS, Guldberg P, Olusen LH, Hokland P. Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients. Eur J Haematol. 2006;76: 23-32.
    • (2006) Eur J Haematol , vol.76 , pp. 23-32
    • Aggerholm, A.1    Holm, M.S.2    Guldberg, P.3    Olusen, L.H.4    Hokland, P.5
  • 29
    • 78650853235 scopus 로고    scopus 로고
    • Aberrant methyl-ation of death-associated protein kinase 1 CpG islands in myelo-dysplastic syndromes
    • Wu X, Liu W, Tian Y, Xiao M, Wu Y, Li C. Aberrant methyl-ation of death-associated protein kinase 1 CpG islands in myelo-dysplastic syndromes. Acta Haematol. 2011;125:179-185.
    • (2011) Acta Haematol , vol.125 , pp. 179-185
    • Wu, X.1    Liu, W.2    Tian, Y.3    Xiao, M.4    Wu, Y.5    Li, C.6
  • 32
    • 14844313747 scopus 로고    scopus 로고
    • 5-Aza-2′-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia
    • Schmelz K, Wagner M, Dörken B, Tamm I. 5-Aza-2′-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia. Int J Cancer. 2005;114:683-695.
    • (2005) Int J Cancer , vol.114 , pp. 683-695
    • Schmelz, K.1    Wagner, M.2    Dörken, B.3    Tamm, I.4
  • 33
    • 32144431895 scopus 로고    scopus 로고
    • Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: A basis for clinical decision making
    • Malcovati L, Della Porta MG, Pascutto C, Invernizzi R, Boni M, Travaglino E, et al Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: a basis for clinical decision making. J Clin Oncol. 2005; 23:7594-603.
    • (2005) J Clin Oncol , vol.23 , pp. 7594-7603
    • Malcovati, L.1    della Porta, M.G.2    Pascutto, C.3    Invernizzi, R.4    Boni, M.5    Travaglino, E.6
  • 34
    • 0033757263 scopus 로고    scopus 로고
    • Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: A retrospective analysis of 1600 patients
    • Germing U, Gattermann N, Strupp C, Alvado M, Aul C. Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients. Leuk Res. 2000;24:983-992.
    • (2000) Leuk Res , vol.24 , pp. 983-992
    • Germing, U.1    Gattermann, N.2    Strupp, C.3    Alvado, M.4    Aul, C.5
  • 35
    • 47249150213 scopus 로고    scopus 로고
    • Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs
    • Rollison DE, Howlader N, Smith MT, Strom SS, Merritt WD, Ries LA, et al Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs. Blood 2008;112:45-52.
    • (2008) Blood , vol.112 , pp. 45-52
    • Rollison, D.E.1    Howlader, N.2    Smith, M.T.3    Strom, S.S.4    Merritt, W.D.5    Ries, L.A.6
  • 36
    • 34247172535 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Ma X, Does M, Raza A, Mayne ST. Myelodysplastic syndromes. Cancer 2007;109:1536-15342.
    • (2007) Cancer , vol.109 , pp. 1536-15342
    • Ma, X.1    Does, M.2    Raza, A.3    Mayne, S.T.4
  • 38
    • 33846011361 scopus 로고    scopus 로고
    • Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • Kantarjian H, Oki Y, Garcia-Manero G, Huang X, O'Brien S, Cortes J, et al Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 2007; 109:52-57.
    • (2007) Blood , vol.109 , pp. 52-57
    • Kantarjian, H.1    Oki, Y.2    Garcia-Manero, G.3    Huang, X.4    O'Brien, S.5    Cortes, J.6    et al7
  • 39
    • 44749094151 scopus 로고    scopus 로고
    • Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome
    • Lin J, Yao D, Qian J, Wang YL, Han LX, Jiang YW, et al Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome. Leuk Res. 2008;32:1541-1545.
    • (2008) Leuk Res , vol.32 , pp. 1541-1545
    • Lin, J.1    Yao, D.2    Qian, J.3    Wang, Y.L.4    Han, L.X.5    Jiang, Y.W.6
  • 40
    • 33749244450 scopus 로고    scopus 로고
    • Clinical implications of SOCS1 methylation in myelodysplastic syndrome
    • Wu SJ, Yao M, Chou WC, Tang JL, Chen CY, Ko BS, et al Clinical implications of SOCS1 methylation in myelodysplastic syndrome. Br J Haematol. 2006;135:317-323.
    • (2006) Br J Haematol , vol.135 , pp. 317-323
    • Wu, S.J.1    Yao, M.2    Chou, W.C.3    Tang, J.L.4    Chen, C.Y.5    Ko, B.S.6
  • 41
    • 77449149371 scopus 로고    scopus 로고
    • DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes
    • Shen L, Kantarjian H, Guo Y, Lin E, Shan J, Huang X, et al DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol. 2010; 28:605-613.
    • (2010) J Clin Oncol , vol.28 , pp. 605-613
    • Shen, L.1    Kantarjian, H.2    Guo, Y.3    Lin, E.4    Shan, J.5    Huang, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.