Understanding epigenetic changes in aging stem cells - a computational model approach

Aging Cell

Volumn 13, Issue 2, 2014, Pages 320-328

  Przybilla, Jens ^a   Rohlf, Thimo ^a,b   Loeffler, Markus ^a   Galle, Joerg ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b MAX PLANCK INSTITUTE FOR MATHEMATICS IN THE SCIENCES   (Germany)

Author keywords

Aging of stem cells; Clonal competition; DNA methylation; Histone modification; Mathematical model; Population dynamics

Indexed keywords

DNA; HISTONE H3; HISTONE METHYLTRANSFERASE; LYSINE;

ARTICLE; CELL AGING; CELL CLONE; CELL HOMING; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; HISTONE METHYLATION; MOLECULAR MECHANICS; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; STEM CELL NICHE;

AGING OF STEM CELLS; CLONAL COMPETITION; DNA METHYLATION; HISTONE MODIFICATION; MATHEMATICAL MODEL; POPULATION DYNAMICS;

CELL AGING; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DNA METHYLATION; EPIGENESIS, GENETIC; FEEDBACK, PHYSIOLOGICAL; HEMATOPOIETIC STEM CELLS; HUMANS; MODELS, BIOLOGICAL; PHENOTYPE; SYSTEMS BIOLOGY;

EID: 84895786009     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12177     Document Type: Article

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