A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity

Experimental Hematology

Volumn 30, Issue 8, 2002, Pages 853-861

  Roeder, Ingo ^a   Loeffler, Markus ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CLONE; CELL DAMAGE; CELL FUNCTION; CELL GROWTH; CELL KINETICS; CELL POPULATION; CELL REGENERATION; COLONY FORMING UNIT S; DYNAMICS; HEMATOPOIETIC STEM CELL; MICROENVIRONMENT; MODEL; NONHUMAN; ORGANIZATION; PLASTICITY; PRIORITY JOURNAL; REVIEW; SIMULATION; STEM CELL; STOCHASTIC MODEL; TISSUE;

EID: 0036322106     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(02)00832-9     Document Type: Article

References (52)

1. Stem cells; attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
2. Stem cells and cellular pedigrees; A conceptual introduction
3. Biology of the haemopoietic stem cell
4. Tissue stem cells; definition, plasticity, heterogeneity, self organization and models-a conceptual approach
5. 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation
6. Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population
7. Heterogeneity of hematopoietic stem cells
8. Searching for hematopoietic stem cells. II. The heterogeneity of Thy-loLin(-/lo)Sca-1+ mouse hematopoietic stem cells separated by counterflow centrifugal elutriation
9. Microenvironmental regulation of hematopoietic stem cells
10. Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation
11. The murine stromal cell line AFT024 acts specifically on human CD34+CD38- progenitors to maintain primitive function and immunophenotype in vitro
12. 'Stem cell candidates' purified by liquid culture in the presence of Steel factor, IL-3, and 5FU are strictly stroma-dependent and have myeloid, lymphoid, and megakaryocytic potential
13. Functional heterogeneity of the hematopoietic microenvironment; rare stromal elements maintain long-term repopulating stem cells
14. Direct contact between CD34+lin- cells and stroma induces a soluble activity that specifically increases primitive hematopoietic cell production
15. Adhesion receptors as regulators of the hematopoietic process
16. Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts
17. The fleet feet of haematopoietic stem cells; rapid motility, interaction and proteopodia
18. Reversible expression of CD34 by murine hematopoietic stem cells
19. Turning brain into blood; a hematopoietic fate adopted by adult neural stem cells in vivo
20. Stem cell plasticity in muscle and bone marrow
21. Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors
22. Stem cell quiescence/activation is reversible by serial transplantation and is independent of stromal cell genotype in mouse aggregation chimeras
23. Evidence that hematopoiesis may be a stochastic process in vivo
24. New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia
25. Chronic myelogenous leukemia
26. Clonal and systemic analysis of long-term hematopoiesis in the mouse
27. Local clonal analysis of the hematopoietic system shows that multiple small short-living clones maintain life-long hematopoiesis in reconstituted mice
28. Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates
29. Neuropilin-1 is expressed on bone marrow stromal cells; a novel interaction with hematopoietic cells?
30. Fibronectin attachment is permissive for IL-1 mediated gene regulation
31. Downregulation of c-kit (stem cell factor receptor) in transformed hematopoietic precursor cells by stroma cells
32. Connexin-43 gap junctions are involved in multiconnexin-expressing stromal support of hemopoietic progenitors and stem cells
33. R; A language for data analysis and graphics
34. Cyclical neutropenia and other periodic hematological disorders; a review of mechanisms and mathematical models
35. Periodic chronic myelogenous leukaemia; spectral analysis of blood cell counts and aetiological implications
36. Autonomous behavior of hematopoietic stem cells
37. Defective regulation of leukemic hematopoiesis in chronic myeloid leukemia
38. Genetic analysis of hemopoietic cell cycling in mice suggests its involvement in organismal lifespan
39. Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice
40. Murine stromal cell line HESS-5 maintains reconstituting ability of ex vivo-generated hematopoietic stem cells from human bone marrow and cytokine-mobilized peripheral blood
41. A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells
42. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
43. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
44. An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse
45. A comprehensive mathematical model of stem cell proliferation which reproduces most of the published experimental results
46. In vivo effects of interleukin-11 and stem cell factor in combination with erythropoietin in the regulation of erythropoiesis
47. Interactions of erythropoietin, granulocyte colony-stimulating factor, stem cell factor, and interleukin-11 on murine hematopoiesis during simultaneous administration
48. The genetic program of hematopoietic stem cells
49. The self renewal probability of hemopoietic stem cells
50. The relationship between the spleen colony-forming cell and the haemopoietic stem cell
51. The stromal cells' guide to the stem cell universe