Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry

Biochemistry

Volumn 52, Issue 51, 2013, Pages 9097-9103

  Mysling, Simon ^a   Betzer, Cristine ^b   Jensen, Poul H ^b   Jorgensen, Thomas J D ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; HYDROGEN BONDS; ISOTOPES; MAGNETIC RESONANCE; MASS SPECTROMETRY; MONOMERS; STRUCTURAL DYNAMICS;

BACKBONE DYNAMICS; C-TERMINAL REGIONS; DYNAMIC REGION; HYDROGEN/DEUTERIUM EXCHANGE; ISOTOPIC EXCHANGE; MEMBRANE BINDING; OLIGOMERIC STATE; PARKINSON'S DISEASE;

OLIGOMERS;

ALPHA SYNUCLEIN; MONOMER; OLIGOMER; SOLVENT; RECOMBINANT PROTEIN; SNCA PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DEUTERIUM HYDROGEN EXCHANGE; DISSOCIATION; ELECTRON SPIN RESONANCE; GEL FILTRATION CHROMATOGRAPHY; HYDROGEN BOND; LIQUID CHROMATOGRAPHY; MEMBRANE BINDING; MOLECULAR STABILITY; NUCLEAR MAGNETIC RESONANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; CHEMICAL PHENOMENA; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR WEIGHT; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; SOLUBILITY;

ALPHA-SYNUCLEIN; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MOLECULAR WEIGHT; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SOLUBILITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84895775448     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4009193     Document Type: Article

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