Berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway

European Journal of Pharmacology

Volumn 730, Issue 1, 2014, Pages 1-7

  Li, Guo Xun ^a   Wang, Xi Mo ^a   Jiang, Tao ^a   Gong, Jian Feng ^b   Niu, Ling Ying ^b   Li, Ning ^b  

^a NANKAI UNIVERSITY AFFILIATED HOSPITAL   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Berberine; Cecal ligation and puncture (CLP); Intestinal mucosal barrier; Intra abdominal infections; Tight junction proteins

Indexed keywords

BERBERINE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CLAUDIN 4; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CELL RECEPTOR; NOD-LIKE RECEPTOR 3, RAT; NOD2 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED STUDY; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; ANIMAL; BLOOD; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PERMEABILITY;

ANIMALS; BERBERINE; CELL DEATH; CLAUDIN-4; GENE EXPRESSION REGULATION; INTERLEUKIN-6; INTESTINAL MUCOSA; MALE; NOD2 SIGNALING ADAPTOR PROTEIN; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEPSIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84895774996     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.02.006     Document Type: Article

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