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Volumn 203, Issue 11, 2011, Pages 1602-1612

Berberine ameliorates intestinal epithelial tight-junction damage and down-regulates myosin light chain kinase pathways in a mouse model of endotoxinemia

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BERBERINE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; MYOSIN LIGHT CHAIN KINASE;

EID: 79956223990     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir147     Document Type: Article
Times cited : (151)

References (40)
  • 1
    • 0028588561 scopus 로고
    • Effect of critical illness on microbial translocation and gastrointestinal mucosa permeability
    • Fink MP. Effect of critical illness on microbial translocation and gastrointestinal mucosa permeability. Semin Respir Infect 1994; 9:256-60.
    • (1994) Semin Respir Infect , vol.9 , pp. 256-260
    • Fink, M.P.1
  • 2
    • 0033868518 scopus 로고    scopus 로고
    • Increased gut permeability and bacterial translocation in Pseudomonas pneumonia-induced sepsis
    • Yu P, Martin CM. Increased gut permeability and bacterial translocation in Pseudomonas pneumonia-induced sepsis. Crit Care Med 2000; 28:2573-7. (Pubitemid 30604472)
    • (2000) Critical Care Medicine , vol.28 , Issue.7 , pp. 2573-2577
    • Yu, P.1    Martin, C.M.2
  • 4
    • 0025579702 scopus 로고
    • Pathobiology of the intestinal epithelial barrier
    • Madara JL. Pathobiology of the intestinal epithelial barrier. Am J Pathol 1990; 137:1273-81.
    • (1990) Am J Pathol , vol.137 , pp. 1273-1281
    • Madara, J.L.1
  • 6
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (Zonula Occludens) in a variety of epithelia
    • DOI 10.1083/jcb.103.3.755
    • Stevenson BR, Siliciano JD, Mooseker MS, Goodenough DA. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol 1986; 103:755-66. (Pubitemid 17177325)
    • (1986) Journal of Cell Biology , vol.103 , Issue.3 , pp. 755-766
    • Stevenson, B.R.1    Siliciano, J.D.2    Mooseker, M.S.3
  • 7
    • 0033571047 scopus 로고    scopus 로고
    • Manner of interaction of heterogeneous claudin species within and between tight junction strands
    • Furuse M, Sasaki H, Tsukita S. Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol 1999; 147:891-903.
    • (1999) J Cell Biol , vol.147 , pp. 891-903
    • Furuse, M.1    Sasaki, H.2    Tsukita, S.3
  • 8
    • 66849089711 scopus 로고    scopus 로고
    • Disruption of tight junctions during polymicrobial sepsis in vivo
    • Li Q, Zhang Q, Wang C, Liu X, Li N, Li J. Disruption of tight junctions during polymicrobial sepsis in vivo. J Pathol 2009; 218:210-21.
    • (2009) J Pathol , vol.218 , pp. 210-221
    • Li, Q.1    Zhang, Q.2    Wang, C.3    Liu, X.4    Li, N.5    Li, J.6
  • 9
    • 34447281675 scopus 로고    scopus 로고
    • Molecular basis of epithelial barrier regulation: From basic mechanisms to clinical application
    • DOI 10.2353/ajpath.2006.060681
    • Turner JR. Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application. Am J Pathol 2006; 169:1901-9. (Pubitemid 351181952)
    • (2006) American Journal of Pathology , vol.169 , Issue.6 , pp. 1901-1909
    • Turner, J.R.1
  • 10
    • 26244450671 scopus 로고    scopus 로고
    • Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats
    • Moriez R, Salvador-Cartier C, Theodorou V, Fioramonti J, Eutamene H, Bueno L. Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats. Am J Pathol 2005; 167:1071-9. (Pubitemid 41416259)
    • (2005) American Journal of Pathology , vol.167 , Issue.4 , pp. 1071-1079
    • Moriez, R.1    Salvador-Cartier, C.2    Theodorou, V.3    Fioramonti, J.4    Eutamene, H.5    Bueno, L.6
  • 11
    • 33644981348 scopus 로고    scopus 로고
    • Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier
    • Ye D, Ma I, Ma TY. Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier. Am J Physiol Gastrointest Liver Physiol 2006; 290:G496-504.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Ye, D.1    Ma, I.2    Ma, T.Y.3
  • 12
    • 47649092211 scopus 로고    scopus 로고
    • How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs
    • Kong DX, Li XJ, Tang GY, Zhang HY. How many traditional Chinese medicine components have been recognized by modern Western medicine? A chemoinformatic analysis and implications for finding multicomponent drugs. ChemMedChem 2008; 3:233-6.
    • (2008) ChemMedChem , vol.3 , pp. 233-236
    • Kong, D.X.1    Li, X.J.2    Tang, G.Y.3    Zhang, H.Y.4
  • 13
    • 0037969021 scopus 로고    scopus 로고
    • Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Zeng XH, Zeng XJ, Li YY. Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 2003; 92:173-6.
    • (2003) Am J Cardiol , vol.92 , pp. 173-176
    • Zeng, X.H.1    Zeng, X.J.2    Li, Y.Y.3
  • 14
    • 0346724714 scopus 로고    scopus 로고
    • The anti-inflammatory potential of berberine in vitro and in vivo
    • Kuo CL, Chi CW, Liu TY. The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett 2004; 203:127-37.
    • (2004) Cancer Lett , vol.203 , pp. 127-137
    • Kuo, C.L.1    Chi, C.W.2    Liu, T.Y.3
  • 15
    • 33748362019 scopus 로고    scopus 로고
    • In vitro antioxidant studies on the benzyl tetra isoquinoline alkaloid berberine
    • Shirwaikar A, Shirwaikar A, Rajendran K, Punitha IS. In vitro antioxidant studies on the benzyl tetra isoquinoline alkaloid berberine. Biol Pharm Bull 2006; 29:1906-10.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1906-1910
    • Shirwaikar, A.1    Shirwaikar, A.2    Rajendran, K.3    Punitha, I.S.4
  • 16
    • 33748924524 scopus 로고    scopus 로고
    • 1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP
    • DOI 10.1093/carcin/bgl043
    • Mantena SK, Sharma SD, Katiyar SK. Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP. Carcinogenesis 2006; 27:2018-27. (Pubitemid 44530576)
    • (2006) Carcinogenesis , vol.27 , Issue.10 , pp. 2018-2027
    • Mantena, S.K.1    Sharma, S.D.2    Katiyar, S.K.3
  • 18
    • 48549105216 scopus 로고    scopus 로고
    • Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis
    • Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis. Cancer Res 2008; 68:5370-9.
    • (2008) Cancer Res , vol.68 , pp. 5370-5379
    • Pandey, M.K.1    Sung, B.2    Kunnumakkara, A.B.3    Sethi, G.4    Chaturvedi, M.M.5    Aggarwal, B.B.6
  • 19
    • 42149084521 scopus 로고    scopus 로고
    • Berberine inhibits cytosolic phospholipase A2 and protects against LPS-induced lung injury and lethality independent of the alpha2-adrenergic receptor in mice
    • Zhang HQ, Wang HD, Lu DX, et al. Berberine inhibits cytosolic phospholipase A2 and protects against LPS-induced lung injury and lethality independent of the alpha2-adrenergic receptor in mice. Shock 2008; 29:617-22.
    • (2008) Shock , vol.29 , pp. 617-622
    • Zhang, H.Q.1    Wang, H.D.2    Lu, D.X.3
  • 20
    • 70350518829 scopus 로고    scopus 로고
    • Berberine differentially modulates the activities of Erk, p38 MAPK and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice
    • Cui G, Qin X, Zhang Y, Gong Z, Ge B, Zang YQ. Berberine differentially modulates the activities of Erk, p38 MAPK and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. J Biol Chem 2009; 284:28420-9.
    • (2009) J Biol Chem , vol.284 , pp. 28420-28429
    • Cui, G.1    Qin, X.2    Zhang, Y.3    Gong, Z.4    Ge, B.5    Zang, Y.Q.6
  • 21
    • 37349108810 scopus 로고    scopus 로고
    • Single bolus injection of bilirubin improves the clinical outcome in a mouse model of endotoxemia
    • DOI 10.1097/shk.0b013e31804d41dd
    • Kadl A, Pontiller J, Exner M, Leitinger N. Single bolus injection of bilirubin improves the clinical outcome in a mouse model of endotoxemia. Shock 2007; 28:582-8. (Pubitemid 350287444)
    • (2007) Shock , vol.28 , Issue.5 , pp. 582-588
    • Kadl, A.1    Pontiller, J.2    Exner, M.3    Leitinger, N.4
  • 22
    • 0014864255 scopus 로고
    • Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal
    • Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN. Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 1970; 101:478-83.
    • (1970) Arch Surg , vol.101 , pp. 478-483
    • Chiu, C.J.1    McArdle, A.H.2    Brown, R.3    Scott, H.J.4    Gurd, F.N.5
  • 23
    • 0242443357 scopus 로고    scopus 로고
    • Reversal of the Effect of Albumin on Gut Barrier Function in Burn by the Inhibition of Inducible Isoform of Nitric Oxide Synthase
    • DOI 10.1001/archsurg.138.11.1219
    • Chen LW, Wang JS, Hwang B, Chen JS, Hsu CM. Reversal of the effect of albumin on gut barrier function in burn by the inhibition of inducible isoform of nitric oxide synthase. Arch Surg 2003; 138:1219-25. (Pubitemid 37392396)
    • (2003) Archives of Surgery , vol.138 , Issue.11 , pp. 1219-1225
    • Chen, L.-W.1    Wang, J.-S.2    Hwang, B.3    Chen, J.-S.4    Hsu, C.-M.5
  • 24
    • 33644850203 scopus 로고    scopus 로고
    • Attaching and effacing pathogen-induced tight junction disruption in vivo
    • DOI 10.1111/j.1462-5822.2005.00656.x
    • Guttman JA, Li Y, Wickham ME, Deng W, Vogl AW, Finlay BB. Attaching and effacing pathogen-induced tight junction disruption in vivo. Cell Microbiol 2006; 8:634-45. (Pubitemid 43372742)
    • (2006) Cellular Microbiology , vol.8 , Issue.4 , pp. 634-645
    • Guttman, J.A.1    Li, Y.2    Wickham, M.E.3    Deng, W.4    Vogl, A.W.5    Finlay, B.B.6
  • 25
    • 77951208947 scopus 로고    scopus 로고
    • Berberine attenuates pro-inflammatory cytokine-induced tight junction disruption in an in vitro model of intestinal epithelial cells
    • Li N, Gu L, Qu L, et al. Berberine attenuates pro-inflammatory cytokine-induced tight junction disruption in an in vitro model of intestinal epithelial cells. Eur J Pharm Sci 2010; 40:1-8.
    • (2010) Eur J Pharm Sci , vol.40 , pp. 1-8
    • Li, N.1    Gu, L.2    Qu, L.3
  • 26
    • 0033979832 scopus 로고    scopus 로고
    • Lipopolysaccharide activates nuclear factor kB in rat intestine: Role of endogenous platelet-activating factor and tumour necrosis factor
    • De Plaen IG, Tan XD, Chang H, Wang L, Remick DG, Hsueh W. Lipopolysaccharide activates nuclear factor kappaB in rat intestine: role of endogenous platelet-activating factor and tumour necrosis factor. Br J Pharmacol 2000; 129:307-14. (Pubitemid 30072651)
    • (2000) British Journal of Pharmacology , vol.129 , Issue.2 , pp. 307-314
    • De Plaen, I.G.1    Tan, X.-D.2    Chang, H.3    Wang, L.4    Remick, D.G.5    Hsueh, W.6
  • 27
    • 67349272274 scopus 로고    scopus 로고
    • The effect of berberine in vitro on tight junctions in human Caco-2 intestinal epithelial cells
    • Gu L, Li N, Li Q, et al. The effect of berberine in vitro on tight junctions in human Caco-2 intestinal epithelial cells. Fitoterapia 2009; 80:241-8.
    • (2009) Fitoterapia , vol.80 , pp. 241-248
    • Gu, L.1    Li, N.2    Li, Q.3
  • 29
    • 0032217262 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is activated in intestinal mucosa during endotoxemia
    • DOI 10.1001/archsurg.133.12.1311
    • Pritts TA, Moon R, Fischer JE, Salzman AL, Hasselgren PO. Nuclear factor-kappaB is activated in intestinal mucosa during endotoxemia. Arch Surg 1998; 133:1311-5. (Pubitemid 29001293)
    • (1998) Archives of Surgery , vol.133 , Issue.12 , pp. 1311-1315
    • Pritts, T.A.1    Moon, M.R.2    Fischer, J.E.3    Salzman, A.L.4    Hasselgren, P.-O.5
  • 30
    • 13844308129 scopus 로고    scopus 로고
    • Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: Role of myosin light-chain kinase protein expression
    • Ma TY, Boivin MA, Ye D, Pedram A, Said HM. Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression. Am J Physiol Gastrointest Liver Physiol 2005; 288:G422-30.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Ma, T.Y.1    Boivin, M.A.2    Ye, D.3    Pedram, A.4    Said, H.M.5
  • 31
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K, Ma TY. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol 2008; 180:5653-61.
    • (2008) J Immunol , vol.180 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 34
    • 67349159840 scopus 로고    scopus 로고
    • Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine
    • Watanabe-Fukuda Y, Yamamoto M, Miura N, et al. Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine. J Gastroenterol 2009; 44:380-9.
    • (2009) J Gastroenterol , vol.44 , pp. 380-389
    • Watanabe-Fukuda, Y.1    Yamamoto, M.2    Miura, N.3
  • 35
    • 77956938319 scopus 로고    scopus 로고
    • Berberine inhibits acute radiation intestinal syndrome in human with abdomen radiotherapy
    • Li GH, Wang DL, Hu YD, et al. Berberine inhibits acute radiation intestinal syndrome in human with abdomen radiotherapy. Med Oncol 2010; 37:919-25.
    • (2010) Med Oncol , vol.37 , pp. 919-925
    • Li, G.H.1    Wang, D.L.2    Hu, Y.D.3
  • 37
    • 0036305854 scopus 로고    scopus 로고
    • A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
    • DOI 10.1053/gast.2002.34235
    • Zolotarevsky Y, Hecht G, Koutsouris A, et al. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 2002; 123:163-72. (Pubitemid 34747537)
    • (2002) Gastroenterology , vol.123 , Issue.1 , pp. 163-172
    • Zolotarevsky, Y.1    Hecht, G.2    Koutsouris, A.3    Gonzalez, D.E.4    Quan, C.5    Tom, J.6    Mrsny, R.J.7    Turner, J.R.8
  • 38
    • 2642576322 scopus 로고    scopus 로고
    • Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice
    • Han X, Fink MP, Yang R, Delude RL. Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice. Shock 2004; 21:261-70.
    • (2004) Shock , vol.21 , pp. 261-270
    • Han, X.1    Fink, M.P.2    Yang, R.3    Delude, R.L.4
  • 39
    • 68049094195 scopus 로고    scopus 로고
    • Bile high-mobility group box 1 contributes to gut barrier dysfunction in experimental endotoxemia
    • Yang R, Miki K, Oksala N, et al. Bile high-mobility group box 1 contributes to gut barrier dysfunction in experimental endotoxemia. Am J Physiol Regul Integr Comp Physiol 2009; 297:R362-9.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297
    • Yang, R.1    Miki, K.2    Oksala, N.3
  • 40
    • 33751511999 scopus 로고    scopus 로고
    • Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry
    • DOI 10.1124/dmd.106.011361
    • Zuo F, Nakamura N, Akao T, Hattori M. Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metab Dispos 2006; 34:2064-72. (Pubitemid 44837767)
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.12 , pp. 2064-2072
    • Zuo, F.1    Nakamura, N.2    Akao, T.3    Hattori, M.4


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