-
1
-
-
34250838558
-
A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation
-
Aldinucci A, Gerlini G, Fossati S, Cipriani G, Ballerini C, Biagioli T, et al. (2007). A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. J Immunol 179: 305-312. (Pubitemid 46986546)
-
(2007)
Journal of Immunology
, vol.179
, Issue.1
, pp. 305-312
-
-
Aldinucci, A.1
Gerlini, G.2
Fossati, S.3
Cipriani, G.4
Ballerini, C.5
Biagioli, T.6
Pimpinelli, N.7
Borgognoni, L.8
Massacesi, L.9
Moroni, F.10
Chiarugi, A.11
-
2
-
-
33846472053
-
H-17 cells in relapsing EAE
-
DOI 10.1038/ni1430, PII NI1430
-
Bailey SL, Schreiner B, McMahon EJ, Miller SD, (2007). CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE. Nat Immunol 8: 172-180. (Pubitemid 46152648)
-
(2007)
Nature Immunology
, vol.8
, Issue.2
, pp. 172-180
-
-
Bailey, S.L.1
Schreiner, B.2
McMahon, E.J.3
Miller, S.D.4
-
3
-
-
0026601666
-
Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase
-
Banasik M, Komura H, Shimoyama M, Ueda K, (1992). Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase. J Biol Chem 267: 1569-1575.
-
(1992)
J Biol Chem
, vol.267
, pp. 1569-1575
-
-
Banasik, M.1
Komura, H.2
Shimoyama, M.3
Ueda, K.4
-
4
-
-
84871856775
-
Therapeutic opportunities for manipulating T(Reg) cells in autoimmunity and cancer
-
von Boehmer H, Daniel C, (2013). Therapeutic opportunities for manipulating T(Reg) cells in autoimmunity and cancer. Nat Rev Drug Discov 12: 51-63.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 51-63
-
-
Von Boehmer, H.1
Daniel, C.2
-
5
-
-
84856651114
-
Targeting poly(ADP-ribose) polymerase-1 as a promising approach for immunomodulation in multiple sclerosis?
-
Cavone L, Chiarugi A, (2012). Targeting poly(ADP-ribose) polymerase-1 as a promising approach for immunomodulation in multiple sclerosis? Trends Mol Med 18: 92-100.
-
(2012)
Trends Mol Med
, vol.18
, pp. 92-100
-
-
Cavone, L.1
Chiarugi, A.2
-
6
-
-
79959493209
-
PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity
-
Cavone L, Aldinucci A, Ballerini C, Biagioli T, Moroni F, Chiarugi A, (2011). PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity. Mult Scler 17: 794-807.
-
(2011)
Mult Scler
, vol.17
, pp. 794-807
-
-
Cavone, L.1
Aldinucci, A.2
Ballerini, C.3
Biagioli, T.4
Moroni, F.5
Chiarugi, A.6
-
7
-
-
0036855413
-
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats
-
DOI 10.1038/sj.bjp.0704934
-
Chiarugi A, (2002a). Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats. Br J Pharmacol 137: 761-770. (Pubitemid 35404175)
-
(2002)
British Journal of Pharmacology
, vol.137
, Issue.6
, pp. 761-770
-
-
Chiarugi, A.1
-
8
-
-
0036499892
-
PARP-1: Killer or conspirator? the suicide hypothesis revisited
-
Chiarugi A, (2002b). PARP-1: killer or conspirator? The suicide hypothesis revisited. Trends Pharmacol Sci 23: 122-129.
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 122-129
-
-
Chiarugi, A.1
-
9
-
-
77949264184
-
Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation
-
Esposito M, Ruffini F, Bellone M, Gagliani N, Battaglia M, Martino G, et al. (2010). Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation. J Neuroimmunol 220: 52-63.
-
(2010)
J Neuroimmunol
, vol.220
, pp. 52-63
-
-
Esposito, M.1
Ruffini, F.2
Bellone, M.3
Gagliani, N.4
Battaglia, M.5
Martino, G.6
-
10
-
-
69049084375
-
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
-
Farez MF, Quintana FJ, Gandhi R, Izquierdo G, Lucas M, Weiner HL, (2009). Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immunol 10: 958-964.
-
(2009)
Nat Immunol
, vol.10
, pp. 958-964
-
-
Farez, M.F.1
Quintana, F.J.2
Gandhi, R.3
Izquierdo, G.4
Lucas, M.5
Weiner, H.L.6
-
11
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
DOI 10.1056/NEJMoa073493
-
Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, et al. (2007). Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357: 851-862. (Pubitemid 47347319)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.W.7
Gabriel, S.B.8
Mirel, D.B.9
Ivinson, A.J.10
Pericak-Vance, M.A.11
Gregory, S.G.12
Rioux, J.D.13
McCauley, J.L.14
Haines, J.L.15
Barcellos, L.F.16
Cree, B.17
Oksenberg, J.R.18
Hauser, S.L.19
-
12
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
DOI 10.1038/nrd1718
-
Jagtap P, Szabo C, (2005). Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4: 421-440. (Pubitemid 40704125)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.5
, pp. 421-440
-
-
Jagtap, P.1
Szabo, C.2
-
13
-
-
23844531504
-
Poly(ADP-ribose) polymerase-1 activation in a primate model of multiple sclerosis
-
DOI 10.1002/jnr.20525
-
Kauppinen TM, Suh SW, Genain CP, Swanson RA, (2005). Poly(ADP-ribose) polymerase-1 activation in a primate model of multiple sclerosis. J Neurosci Res 81: 190-198. (Pubitemid 41153332)
-
(2005)
Journal of Neuroscience Research
, vol.81
, Issue.2
, pp. 190-198
-
-
Kauppinen, T.M.1
Suh, S.W.2
Genain, C.P.3
Swanson, R.A.4
-
14
-
-
77954326944
-
Animal research: Reporting in vivo experiments: The ARRIVE guidelines
-
Kilkenny C, Browne W, Cuthill IC, Emerson M, Altman DG, (2010). Animal research: reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol 160: 1577-1579.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1577-1579
-
-
Kilkenny, C.1
Browne, W.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
15
-
-
0024361208
-
Differential role for ADP-ribosylation in gene expression during the activation of T lymphocytes by various stimuli
-
King SL, McNerney R, Withely GS, Johnstone AP, (1989). Differential role for ADP-ribosylation in gene expression during the activation of T lymphocytes by various stimuli. Immunology 67: 258-262. (Pubitemid 19151481)
-
(1989)
Immunology
, vol.67
, Issue.2
, pp. 258-262
-
-
King, S.L.1
McNerney, R.2
Whitley, G.S.3
Johnstone, A.P.4
-
16
-
-
44649130038
-
Transcriptional control by PARP-1: Chromatin modulation, enhancer-binding, coregulation, and insulation
-
Kraus WL, (2008). Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation. Curr Opin Cell Biol 20: 294-302.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 294-302
-
-
Kraus, W.L.1
-
17
-
-
0038682011
-
PARP goes transcription
-
DOI 10.1016/S0092-8674(03)00433-1
-
Kraus WL, Lis JT, (2003). PARP goes transcription. Cell 113: 677-683. (Pubitemid 36724932)
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 677-683
-
-
Kraus, W.L.1
Lis, J.T.2
-
18
-
-
77954274504
-
The PARP side of the nucleus: Molecular actions, physiological outcomes, and clinical targets
-
Krishnakumar R, Kraus WL, (2010). The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell 39: 8-24.
-
(2010)
Mol Cell
, vol.39
, pp. 8-24
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
19
-
-
0036715411
-
Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
-
DOI 10.1016/S1471-4906(02)02281-0, PII S1471490602022810
-
Lutz MB, Schuler G, (2002). Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23: 445-449. (Pubitemid 35015188)
-
(2002)
Trends in Immunology
, vol.23
, Issue.9
, pp. 445-449
-
-
Lutz, M.B.1
Schuler, G.2
-
20
-
-
77954331629
-
Guidelines for reporting experiments involving animals: The ARRIVE guidelines
-
McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1573-1576
-
-
McGrath, J.1
Drummond, G.2
McLachlan, E.3
Kilkenny, C.4
Wainwright, C.5
-
21
-
-
16244417773
-
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
-
DOI 10.1038/nm1202
-
McMahon EJ, Bailey SL, Castenada CV, Waldner H, Miller SD, (2005). Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 11: 335-339. (Pubitemid 40460563)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 335-339
-
-
McMahon, E.J.1
Bailey, S.L.2
Castenada, C.V.3
Waldner, H.4
Miller, S.D.5
-
22
-
-
0024465467
-
Changes of mRNA levels of poly(ADP-ribose) polymerase during activation of human lymphocytes
-
McNerney R, Tavasolli M, Shall S, Brazinski A, Johnstone AP, (2001). Changes of mRNA levels of poly(ADP-ribose) polymerase during activation of human lymphocytes. Biochim Biophys Acta 1009: 185-187.
-
(2001)
Biochim Biophys Acta
, vol.1009
, pp. 185-187
-
-
McNerney, R.1
Tavasolli, M.2
Shall, S.3
Brazinski, A.4
Johnstone, A.P.5
-
23
-
-
79954506102
-
Dendritic cell control of tolerogenic responses
-
Manicassamy S, Pulendran B, (2011). Dendritic cell control of tolerogenic responses. Immunol Rev 241: 206-227.
-
(2011)
Immunol Rev
, vol.241
, pp. 206-227
-
-
Manicassamy, S.1
Pulendran, B.2
-
24
-
-
77951634464
-
Increased Foxp3+ regulatory T cells in poly(ADP-ribose) polymerase-1 deficiency
-
Nasta F, Laudisi F, Sambucci M, Rosado MM, Pioli C, (2010). Increased Foxp3+ regulatory T cells in poly(ADP-ribose) polymerase-1 deficiency. J Immunol 184: 3470-3477.
-
(2010)
J Immunol
, vol.184
, pp. 3470-3477
-
-
Nasta, F.1
Laudisi, F.2
Sambucci, M.3
Rosado, M.M.4
Pioli, C.5
-
25
-
-
55949092708
-
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
-
Rottenberg S, Jaspers JE, Kersbergen A, van der Burg E, Nygren AO, Zander SA, et al.(2008). High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci U.S.A 105: 17079-17084.
-
(2008)
Proc Natl Acad Sci U.S.A
, vol.105
, pp. 17079-17084
-
-
Rottenberg, S.1
Jaspers, J.E.2
Kersbergen, A.3
Van Der Burg, E.4
Nygren, A.O.5
Zander, S.A.6
-
26
-
-
3242677783
-
Regulatory T cells and tolerogenic dendritic cells: From basic biology to clinical applications
-
DOI 10.1016/j.imlet.2004.04.015, PII S0165247804001166
-
Rutella S, Lemoli RM, (2004). Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications. Immunol Lett 94: 11-26. (Pubitemid 38953707)
-
(2004)
Immunology Letters
, vol.94
, Issue.1-2
, pp. 11-26
-
-
Rutella, S.1
Lemoli, R.M.2
-
27
-
-
0035796895
-
Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis
-
DOI 10.1016/S0165-5728(01)00329-0, PII S0165572801003290
-
Scott GS, Hake P, Kean RB, Virag L, Szabo C, Hooper DC, (2001). Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis. J Neuroimmunol 117: 78-86. (Pubitemid 32595495)
-
(2001)
Journal of Neuroimmunology
, vol.117
, Issue.1-2
, pp. 78-86
-
-
Scott, G.S.1
Hake, P.2
Kean, R.B.3
Virag, L.4
Szabo, C.5
Hooper, D.C.6
-
28
-
-
4243068535
-
The therapeutic effects of PJ34. [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl) - N,N-dimethylacetamide, HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation
-
DOI 10.1124/jpet.103.063214
-
Scott GS, Kean RB, Mikheeva T, Fabis MJ, Mabley JG, Szabo C, et al. (2004). The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl) -N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation. J Pharmacol Exp Ther 310: 1053-1061. (Pubitemid 39108927)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.310
, Issue.3
, pp. 1053-1061
-
-
Scott, G.S.1
Kean, R.B.2
Mikheeva, T.3
Fabis, M.J.4
Mabley, J.G.5
Szabo, C.6
Hooper, D.C.7
-
29
-
-
77952521698
-
Immunogenic versus tolerogenic dendritic cells: A matter of maturation
-
Tisch R, (2010). Immunogenic versus tolerogenic dendritic cells: a matter of maturation. Int Rev Immunol 29: 111-118.
-
(2010)
Int Rev Immunol
, vol.29
, pp. 111-118
-
-
Tisch, R.1
-
30
-
-
0034576057
-
Epitope spreading: A mechanism for progression of autoimmune disease
-
Tuohy VK, Kinkel RP, (2000). Epitope spreading: a mechanism for progression of autoimmune disease. Arch Immunol Ther Exp (Warsz) 48: 347-351.
-
(2000)
Arch Immunol Ther Exp (Warsz)
, vol.48
, pp. 347-351
-
-
Tuohy, V.K.1
Kinkel, R.P.2
-
31
-
-
0036481263
-
Epitope spreading in immune-mediated diseases: Implications for immunotherapy
-
Vanderlugt CL, Miller SD, (2002). Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat Rev Immunol 2: 85-95. (Pubitemid 37323232)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.2
, pp. 85-95
-
-
Vanderlugt, C.L.1
Miller, S.D.2
-
32
-
-
17344363488
-
The functional significance of epitope spreading and its regulation by co-stimulatory molecules
-
DOI 10.1111/j.1600-065X.1998.tb01208.x
-
Vanderlugt CL, Begolka WS, Neville KL, Katz-Levy Y, Howard LM, Eagar TN, et al. (1998). The functional significance of epitope spreading and its regulation by co-stimulatory molecules. Immunol Rev 164: 63-72. (Pubitemid 28438396)
-
(1998)
Immunological Reviews
, vol.164
, pp. 63-72
-
-
Vanderlugt, C.L.1
Begolka, W.S.2
Neville, K.L.3
Katz-Levy, Y.4
Howard, L.M.5
Eagar, T.N.6
Bluestone, J.A.7
Miller, S.D.8
-
33
-
-
0029073251
-
Immunosuppressive activities of 6(5)-phenanthridinone, a new poly(ADP-ribose) polymerase inhibitor
-
Weltin D, Picard K, Aupeix K, Varin M, Oth D, Marchal J, et al. (1995). Immunosuppressive activities of 6(5)-phenanthridinone, a new poly(ADP-ribose) polymerase inhibitor. Int J Immunopharmacol 17: 265-271.
-
(1995)
Int J Immunopharmacol
, vol.17
, pp. 265-271
-
-
Weltin, D.1
Picard, K.2
Aupeix, K.3
Varin, M.4
Oth, D.5
Marchal, J.6
-
34
-
-
79951821948
-
Poly(ADP-ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic
-
Yap TA, Sandhu SK, Carden CP, de Bono JS, (2011). Poly(ADP-ribose) polymerase (PARP) inhibitors: exploiting a synthetic lethal strategy in the clinic. CA Cancer J Clin 61: 31-49.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 31-49
-
-
Yap, T.A.1
Sandhu, S.K.2
Carden, C.P.3
De Bono, J.S.4
-
35
-
-
84895751735
-
PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3
-
Zhang P, Maruyama T, Konkel JE, Abbatiello B, Zamarron B, Wang ZQ, et al. (2013). PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3. PLoS ONE 8: e71590.
-
(2013)
PLoS ONE
, vol.8
-
-
Zhang, P.1
Maruyama, T.2
Konkel, J.E.3
Abbatiello, B.4
Zamarron, B.5
Wang, Z.Q.6
|