A Virtual Infection Model Quantifies Innate Effector Mechanisms and Candida albicans Immune Escape in Human Blood

PLoS Computational Biology

Volumn 10, Issue 2, 2014, Pages

  Hünniger, Kerstin ^a   Lehnert, Teresa ^a,b   Bieber, Kristin ^a   Martin, Ronny ^a   Figge, Marc Thilo ^a,b   Kurzai, Oliver ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Applied Systems Biology Leibniz Institute for Natural Product Research and Infection Biology Hans Knöll Inst HKI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; BLOOD; CANDIDA; CYTOLOGY; ENZYME ACTIVITY; IMMUNE SYSTEM; ITERATIVE METHODS; MONTE CARLO METHODS; PATHOGENS; SIMULATED ANNEALING; SIMULATORS; VIRTUAL REALITY; YEAST;

ALBICANS; ANTIFUNGALS; CANDIDA ALBICANS; FUNGAL CELLS; HOST-PATHOGEN INTERACTIONS; HUMAN BLOODS; INFECTION MODELS; PHAGOCYTOSE; QUANTITATIVE PREDICTION; WHOLE BLOOD;

CELLS;

ARTICLE; BLOOD SAMPLING; BLOODSTREAM INFECTION; CANDIDA ALBICANS; CELL COUNT; CELL KILLING; CELL VIABILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DYNAMICS; FUNGAL CELL; FUNGICIDAL ACTIVITY; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INNATE IMMUNITY; INOCULATION; LEUKOCYTE; MATHEMATICAL MODEL; MICROFILAMENT; MONOCYTE; MONTE CARLO METHOD; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PHASE TRANSITION; PREDICTION; QUANTITATIVE ANALYSIS; BIOLOGICAL MODEL; BIOLOGY; BLOOD; CANDIDEMIA; COMPUTER INTERFACE; COMPUTER SIMULATION; CROSS INFECTION; IMMUNOLOGY; MATHEMATICAL PHENOMENA; MICROBIOLOGY; PATHOGENICITY;

CANDIDA ALBICANS; CANDIDEMIA; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CROSS INFECTION; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; MATHEMATICAL CONCEPTS; MODELS, IMMUNOLOGICAL; MONOCYTES; MONTE CARLO METHOD; NEUTROPHILS; PHAGOCYTOSIS; USER-COMPUTER INTERFACE;

EID: 84895747383     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003479     Document Type: Article

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