메뉴 건너뛰기




Volumn 33, Issue 2, 2014, Pages 333-343

High glucose concentration stimulates NHE-1 activity in distal nephron cells: The role of the Mek/Erk1/2/p90 and p38MAPK signaling pathways

Author keywords

Erk1 2; Glucose; MDCK cells; NHE 1; p38MAPK

Indexed keywords

(3 METHYLSULFONYL 4 PIPERIDINOBENZOYL)GUANIDINE METHANESULFONATE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; FLUORESCENT DYE; GLUCOSE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P90RSK; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; PROTEIN P90;

EID: 84895616277     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356673     Document Type: Article
Times cited : (26)

References (40)
  • 3
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • Wright EM, Loo DD, Hirayama BA: Biology of human sodium glucose transporters; Physiol Rev 2011;91:733-794.
    • (2011) Physiol Rev , vol.91 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.2    Hirayama, B.A.3
  • 4
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J: Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes; Diabetes 2005;54:3427-3434.
    • (2005) Diabetes , vol.54 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 6
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M: Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing sp1 glycosylation. Proc Natl Acad Sci USA 2000;97:12222-12226.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6    Wu, J.7    Brownlee, M.8
  • 7
    • 84886424419 scopus 로고    scopus 로고
    • Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress
    • Friederich-Persson M, Thörn E, Hansell P, Nangaku M, Levin M, Palm F: Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress. Hypertension 2013;62:914-919.
    • (2013) Hypertension , vol.62 , pp. 914-919
    • Friederich-Persson, M.1    Thörn, E.2    Hansell, P.3    Nangaku, M.4    Levin, M.5    Palm, F.6
  • 8
    • 0018711442 scopus 로고
    • The effect of streptozotocin-induced diabetes on glycogen metabolism in rat kidney and its relationship to the liver system
    • Khandelwal RL, Zinman SM, Knull HR: The effect of streptozotocin-induced diabetes on glycogen metabolism in rat kidney and its relationship to the liver system. Arch Biochem Biophys 1979;197:310-316.
    • (1979) Arch Biochem Biophys , vol.197 , pp. 310-316
    • Khandelwal, R.L.1    Zinman, S.M.2    Knull, H.R.3
  • 9
    • 0023258423 scopus 로고
    • Angiotensin receptor subtypes of the kidney cortex
    • Douglas JG: Angiotensin receptor subtypes of the kidney cortex. Am J Physiol 1987;253:F1-7.
    • (1987) Am J Physiol , vol.253
    • Douglas, J.G.1
  • 10
    • 0030719439 scopus 로고    scopus 로고
    • Differential activities of H+ extrusion systems in mdck cells due to extracellular osmolality and ph
    • Feifel E, Krall M, Geibel JP, Pfaller W: Differential activities of H+ extrusion systems in mdck cells due to extracellular osmolality and ph. Am J Physiol 1997;273:F499-506.
    • (1997) Am J Physiol , vol.273
    • Feifel, E.1    Krall, M.2    Geibel, J.P.3    Pfaller, W.4
  • 11
    • 4644313971 scopus 로고    scopus 로고
    • The Na+/H+ exchanger isoform 1
    • Fliegel L: The Na+/H+ exchanger isoform 1; Int J Biochem Cell Biol 2005;37:33-37.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 33-37
    • Fliegel, L.1
  • 12
    • 34248190912 scopus 로고    scopus 로고
    • Cell confluence-induced activation of signal transducer and activator of transcription-3 (stat3) triggers epithelial dome formation via augmentation of sodium hydrogen exchanger-3 (nhe3) expression
    • Su HW, Yeh HH, Wang SW, Shen MR, Chen TL, Kiela PR, Ghishan FK, Tang MJ: Cell confluence-induced activation of signal transducer and activator of transcription-3 (stat3) triggers epithelial dome formation via augmentation of sodium hydrogen exchanger-3 (nhe3) expression. J Biol Chem 2007;282:9883-9894.
    • (2007) J Biol Chem , vol.282 , pp. 9883-9894
    • Su, H.W.1    Yeh, H.H.2    Wang, S.W.3    Shen, M.R.4    Chen, T.L.5    Kiela, P.R.6    Ghishan, F.K.7    Tang, M.J.8
  • 13
    • 1242272754 scopus 로고    scopus 로고
    • Diversity of the mammalian sodium/proton exchanger slc9 gene family
    • Orlowski J, Grinstein S: Diversity of the mammalian sodium/proton exchanger slc9 gene family. Pflugers Arch 2004;447:549-565.
    • (2004) Pflugers Arch , vol.447 , pp. 549-565
    • Orlowski, J.1    Grinstein, S.2
  • 14
    • 40949103035 scopus 로고    scopus 로고
    • Nhe10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected]
    • Lee SH, Kim T, Park ES, Yang S, Jeong D, Choi Y, Rho J: Nhe10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected]. Biochem Biophys Res Commun 2008;369:320-326.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 320-326
    • Lee, S.H.1    Kim, T.2    Park, E.S.3    Yang, S.4    Jeong, D.5    Choi, Y.6    Rho, J.7
  • 15
    • 0026495612 scopus 로고
    • Immunocytochemical characterization of Na+/H+ exchanger isoform nhe-1 in rabbit kidney
    • Biemesderfer D, Reilly RF, Exner M, Igarashi P, Aronson PS: Immunocytochemical characterization of Na+/H+ exchanger isoform nhe-1 in rabbit kidney. Am J Physiol 1992;263:F833-840.
    • (1992) Am J Physiol , vol.263
    • Biemesderfer, D.1    Reilly, R.F.2    Exner, M.3    Igarashi, P.4    Aronson, P.S.5
  • 17
    • 50949126564 scopus 로고    scopus 로고
    • Involvement of Na+/H+ exchanger 1 in advanced glycation end products-induced proliferation of vascular smooth muscle cell
    • Wu S, Song T, Zhou S, Liu Y, Chen G, Huang N, Liu L: Involvement of Na+/H+ exchanger 1 in advanced glycation end products-induced proliferation of vascular smooth muscle cell. Biochem Biophys Res Commun 2008;375:384-389.
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 384-389
    • Wu, S.1    Song, T.2    Zhou, S.3    Liu, Y.4    Chen, G.5    Huang, N.6    Liu, L.7
  • 20
    • 0034677758 scopus 로고    scopus 로고
    • A novel topology model of the human Na+/H+ exchanger isoform 1
    • Wakabayashi S, Pang T, Su X, Shigekawa M: A novel topology model of the human Na+/H+ exchanger isoform 1. J Biol Chem 2000;275:7942-7949.
    • (2000) J Biol Chem , vol.275 , pp. 7942-7949
    • Wakabayashi, S.1    Pang, T.2    Su, X.3    Shigekawa, M.4
  • 21
    • 0032695140 scopus 로고    scopus 로고
    • E Regulation of sarcolemmal Na+/H+ exchanger activity by angiotensin ii in adult rat ventricular myocytes: Opposing actions via at (1) versus at(2) receptors
    • Gunasegaram S, Haworth RS, Hearse DJ, Avkiran M: Regulation of sarcolemmal Na+/H+ exchanger activity by angiotensin ii in adult rat ventricular myocytes: Opposing actions via at(1) versus at(2) receptors. Circ Res 1999;85:919-930.
    • (1999) Circ Res , vol.85 , pp. 919-930
    • Gunasegaram, S.1    Haworth, R.S.2    Hearse, D.J.3    Avkiran, M.4
  • 22
    • 0029737292 scopus 로고    scopus 로고
    • Differential targeting of facilitative glucose transporters in polarized epithelial cells
    • Pascoe WS, Inukai K, Oka Y, Slot JW, James DE: Differential targeting of facilitative glucose transporters in polarized epithelial cells. Am J Physiol 1996;271:C547-554.
    • (1996) Am J Physiol , vol.271
    • Pascoe, W.S.1    Inukai, K.2    Oka, Y.3    Slot, J.W.4    James, D.E.5
  • 23
    • 0034780077 scopus 로고    scopus 로고
    • Trophic factor withdrawal: P38 mitogen-Activated protein kinase activates nhe1, which induces intracellular alkalinization
    • Khaled AR, Moor AN, Li A, Kim K, Ferris DK, Muegge K, Fisher RJ, Fliegel L, Durum SK: Trophic factor withdrawal: P38 mitogen-Activated protein kinase activates nhe1, which induces intracellular alkalinization. Mol Cell Biol 2001;21:7545-7557.
    • (2001) Mol Cell Biol , vol.21 , pp. 7545-7557
    • Khaled, A.R.1    Moor, A.N.2    Li, A.3    Kim, K.4    Ferris, D.K.5    Muegge, K.6    Fisher, R.J.7    Fliegel, L.8    Durum, S.K.9
  • 24
    • 34948831682 scopus 로고    scopus 로고
    • Erk1/2-p90rsk-mediated phosphorylation of Na+/H+ exchanger isoform 1. A role in ischemic neuronal death
    • Luo J, Kintner DB, Shull GE, Sun D: Erk1/2-p90rsk-mediated phosphorylation of Na+/H+ exchanger isoform 1. A role in ischemic neuronal death; J Biol Chem 2007;282:28274-28284.
    • (2007) J Biol Chem , vol.282 , pp. 28274-28284
    • Luo, J.1    Kintner, D.B.2    Shull, G.E.3    Sun, D.4
  • 25
    • 0029934130 scopus 로고    scopus 로고
    • Differential localization of Na+/H+ exchanger isoforms (nhe1 and nhe3) in polarized epithelial cell lines
    • Noel J, Roux D, Pouysségur J: Differential localization of Na+/H+ exchanger isoforms (nhe1 and nhe3) in polarized epithelial cell lines. J Cell Sci 1996;109:929-939.
    • (1996) J Cell Sci , vol.109 , pp. 929-939
    • Noel, J.1    Roux, D.2    Pouysségur, J.3
  • 26
    • 84880996014 scopus 로고    scopus 로고
    • Acidosis-mediated regulation of the nhe1 isoform of the Na+/H+ exchanger in renal cells
    • Odunewu A, Fliegel L: Acidosis-mediated regulation of the nhe1 isoform of the Na+/H+ exchanger in renal cells. Am J Physiol Renal Physiol 2013;305:F370-381.
    • (2013) Am J Physiol Renal Physiol , vol.305
    • Odunewu, A.1    Fliegel, L.2
  • 27
    • 84890124294 scopus 로고    scopus 로고
    • The regulation of nhe1 and nhe3 activity by angiotensin ii is mediated by the activation of the angiotensin ii type i receptor/phospholipase c/calcium/calmodulin pathway in distal nephron cells
    • Costa-Pessoa JM, Figueiredo CF, Thieme K, Oliveira-Souza M: The regulation of nhe1 and nhe3 activity by angiotensin ii is mediated by the activation of the angiotensin ii type i receptor/phospholipase c/calcium/calmodulin pathway in distal nephron cells. Eur J Pharmacol 2013;721:322-331.
    • (2013) Eur J Pharmacol , vol.721 , pp. 322-331
    • Costa-Pessoa, J.M.1    Figueiredo, C.F.2    Thieme, K.3    Oliveira-Souza, M.4
  • 28
    • 52749087919 scopus 로고    scopus 로고
    • The effect of angiotensin ii on intracellular ph is mediated by at (1) receptor translocation
    • Thieme K, Eguti DM, Mello-Aires M, Oliveira-Souza M: The effect of angiotensin ii on intracellular ph is mediated by at(1) receptor translocation; Am J Physiol Cell Physiol 2008;295:C138-145.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Thieme, K.1    Eguti, D.M.2    Mello-Aires, M.3    Oliveira-Souza, M.4
  • 29
    • 78149425568 scopus 로고    scopus 로고
    • Regulation of Na+/H+ exchanger isoform 1 (nhe1) by calmodulin-binding sites: Role of angiotensin ii
    • Eguti DMN, Thieme K, Leung GP, Mello-Aires M, Oliveira-Souza M: Regulation of Na+/H+ exchanger isoform 1 (nhe1) by calmodulin-binding sites: Role of angiotensin ii. Cell Physiol Biochem 2010;26:541-552.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 541-552
    • Eguti, D.M.N.1    Thieme, K.2    Leung, G.P.3    Mello-Aires, M.4    Oliveira-Souza, M.5
  • 30
    • 0036174658 scopus 로고    scopus 로고
    • The changing face of the Na+/H+ exchanger, nhe1: Structure, regulation, and cellular actions
    • Putney LK, Denker SP, Barber DL: The changing face of the Na+/H+ exchanger, nhe1: Structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol 2002;42:527-552.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 527-552
    • Putney, L.K.1    Denker, S.P.2    Barber, D.L.3
  • 31
    • 0017278905 scopus 로고
    • Intracellular ph transients in squid giant axons caused by co2, nh3, and metabolic inhibitors
    • Boron WF, De Weer P: Intracellular ph transients in squid giant axons caused by co2, nh3, and metabolic inhibitors. J Gen Physiol 1976;67:91-112.
    • (1976) J Gen Physiol , vol.67 , pp. 91-112
    • Boron, W.F.1    De Weer, P.2
  • 32
    • 0033696969 scopus 로고    scopus 로고
    • Interaction of angiotensin ii and atrial natriuretic peptide on ph (i) regulation in mdck cells
    • Oliveira-Souza M, De Mello-Aires M: Interaction of angiotensin ii and atrial natriuretic peptide on ph(i) regulation in mdck cells. Am J Physiol Renal Physiol 2000;279:F944-953.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Oliveira-Souza, M.1    De Mello-Aires, M.2
  • 33
    • 0033575236 scopus 로고    scopus 로고
    • P90(rsk) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1
    • Takahashi E, Abe J, Gallis B, Aebersold R, Spring DJ, Krebs EG, Berk BC: P90(rsk) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1. J Biol Chem 1999;274:20206-20214.
    • (1999) J Biol Chem , vol.274 , pp. 20206-20214
    • Takahashi, E.1    Abe, J.2    Gallis, B.3    Aebersold, R.4    Spring, D.J.5    Krebs, E.G.6    Berk, B.C.7
  • 34
    • 0035844144 scopus 로고    scopus 로고
    • 14-3-3 binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange
    • Lehoux S, Abe J, Florian JA, Berk BC: 14-3-3 binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange; J Biol Chem 2001;276:15794-15800.
    • (2001) J Biol Chem , vol.276 , pp. 15794-15800
    • Lehoux, S.1    Abe, J.2    Florian, J.A.3    Berk, B.C.4
  • 35
    • 0035844256 scopus 로고    scopus 로고
    • Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium
    • Moor AN, Gan XT, Karmazyn M, Fliegel L: Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium; J Biol Chem 2001;276:16113-16122.
    • (2001) J Biol Chem , vol.276 , pp. 16113-16122
    • Moor, A.N.1    Gan, X.T.2    Karmazyn, M.3    Fliegel, L.4
  • 36
    • 33747705507 scopus 로고    scopus 로고
    • Mapkapk-2 is a critical signaling intermediate in nhe3 activation following Na+-glucose cotransport
    • Hu Z, Wang Y, Graham WV, Su L, Musch MW, Turner JR: Mapkapk-2 is a critical signaling intermediate in nhe3 activation following Na+-glucose cotransport. J Biol Chem 2006;281:24247-24253.
    • (2006) J Biol Chem , vol.281 , pp. 24247-24253
    • Hu, Z.1    Wang, Y.2    Graham, W.V.3    Su, L.4    Musch, M.W.5    Turner, J.R.6
  • 37
    • 84869223394 scopus 로고    scopus 로고
    • 2-deoxy-d-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: Involvement of igf-1r-regulated akt/mtor, mek/erk and lkb-1/ampk signaling pathways
    • Estañ MC, Calviño E, de Blas E, Boyano-Adánez MeC, Mena ML, Gómez-Gómez M, Rial E, Aller P: 2-deoxy-d-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: Involvement of igf-1r-regulated akt/mtor, mek/erk and lkb-1/ampk signaling pathways. Biochem Pharmacol 2012;84:1604-1616.
    • (2012) Biochem Pharmacol , vol.84 , pp. 1604-1616
    • Estañ, M.C.1    Calviño, E.2    De Blas, E.3    Boyano Adánez, M.E.C.4    Mena, M.L.5    Gómez-Gómez, M.6    Rial, E.7    Aller, P.8
  • 40
    • 0033963490 scopus 로고    scopus 로고
    • High glucose induces the activity and expression of Na+/H+ exchange in glomerular mesangial cells
    • Ganz MB, Hawkins K, Reilly RF: High glucose induces the activity and expression of Na+/H+ exchange in glomerular mesangial cells. Am J Physiol Renal Physiol 2000;278:F91-96.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Ganz, M.B.1    Hawkins, K.2    Reilly, R.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.