Differential localization of Na+/H+ exchanger isoforms (NHE1 and NHE3) in polarized epithelial cell lines

Journal of Cell Science

Volumn 109, Issue 5, 1996, Pages 929-939

  Noel, Josette ^a   Roux, Danièle ^a   Pouysségur, Jacques ^a  

^a CNRS   (France)

Author keywords

H+ exchanger; Na+; NHE isoform

Indexed keywords

BIOTIN; CARRIER PROTEIN; CELL SURFACE PROTEIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL CULTURE; CELL MEMBRANE; CELL POLARITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DNA TRANSFECTION; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTON SODIUM EXCHANGE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; CELL POLARITY; CRICETINAE; CRICETULUS; DOGS; EPITHELIAL CELLS; MOLECULAR SEQUENCE DATA; OPOSSUMS; SODIUM-HYDROGEN ANTIPORTER; TRANSFECTION;

ANIMALIA; EUKARYOTA;

EID: 0029934130     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Auffray, C. and Rougeon, F. (1980). Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur. J. Biochem. 107, 303-314.
2. + exchanger isoform NHE-1 in rabbit kidney. Am. J. Physiol. 263, F833-F840.
3. + exchanger isoform of the renal brush border. Am. J. Physiol. 265, F736-F742.
4. + antiport to osmotic stress. Am. J. Physiol. 269, C998-C1007.
5. + exchangers, NHE1 and NHE3 of rat intestine. Expression and localization. J. Clin. Invest. 93, 106-113.
6. + exchanger subtypes, a predictive review. Am. J. Physiol. 261, C945-C953.
7. + antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties. Mol. Pharmacol. 44, 1041-1045.
8. + exchanger gene (NHE1) and amplification of the mutated allele confer amiloride-resistance upon chronic acidosis. Proc. Nat. Acad. Sci. USA 90, 4508-4512.
9. + exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain. Biochemistry 33, 10463-10469.
10. Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A. and Rutter, W. J. (1986). Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell 45, 721-732.
11. + exchanger isoforms NHE1 and NHE3 exist as stable dimers in membranes with a high degree of specificity for homodimers. J. Biol. Chem. 269, 2589-2596.
12. Ghosh, S., Freitag, A., Martin-Vassalo, P. and Coca-Prados, M. (1990). Cellular distribution and differential gene expression of the three α-subunit isoforms of the Na,K-ATPase in the ocular ciliary epithelium. J. Biol. Chem. 265, 2935-2940.
13. Gottardi, C. and Caplan, M. (1993). An ion-transporting ATPase encodes multiple apical localization signals. J. Cell Biol. 121, 283-293.
14. + exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochim. Biophys. Acta 988, 73-97.
15. Gunderson, D., Orlowski, J. and Rodriguez-Boulan, E. (1991). Apical polarity of Na,K-ATPase in retinal pigment epithelium is linked to a reversal of the ankyrin-fodrin submembrane cytoskeleton. J. Cell Biol. 112, 863-872.
16. +-ATPase in polarized epithelial cells. Science 254, 847-850.
17. + exchange in opossum kidney cells, polarity and mechanisms. Pflügers Arch. 416, 615-623.
18. + exchange activities in NHE1-transfected OK-cells, cell polarity and regulation. Pflügers Arch. 425, 34-40.
19. 2A-adrenergic receptor is targeted directly to the basolateral membrane domain of MDCK cells independent of coupling to pertussis toxin-sensitive GTP-binding proteins. J. Biol. Chem. 268, 11340-11347.
20. + exchanger (NHE5/SLC9A5) to chromosome 16q22.1. Genomics 25, 615-622.
21. Kreis, T. E. (1986). Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface. EMBO J. 5, 931-941.
22. + exchangers, NHE-1 in the maternal-facing (brush-border) membrane and NHE-2 in the fetal-facing (basal) membrane. Biochem. J. 284, 33-38.
23. Le Bivic, A., Real, F. X. and Rodriguez-Boulan, E. (1989). Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc. Nat. Acad. Sci. USA 86, 9313-9317.
24. Le Bivic, A., Sambuy, Y., Patzak, A., Patil, N., Chao, M. and Rodriguez-Boulan, E. (1991). An internal deletion in the cytoplamic tail reverses the apical localization of human NGF receptor in transfected MDCK cells. J. Cell Biol. 115, 607-618.
25. Marrs, J. A., Andersson-Fisone, C., Jeong, M. C., Cohen-Gould, L., Zurzolo, C., Nabi, I. R., Rodriguez-Boulan, E. and Nelson, W. J. (1995). Plasticity in epithelial cell phenotype, modulation by expression of different cadherin cell adhesion molecules. J. Cell Biol. 129, 507-519.
26. Matter, K., Hunziker, W. and Mellman, I. (1992). Basolateral sorting of LDL receptor in MDCK cells, the cytoplasmic domain contains two tyrosine-dependent targeting determinants. Cell 71, 741-753.
27. Matter, K. and Mellman, I. (1994). Mechanisms of cell polarity, sorting and transport in epithelial cells. Curr. Opin. Cell Biol. 6, 545-554.
28. + exchange in cultured opposum kidney (OK) cells. Am. J. Physiol. 259, C-121-C133.
29. + exchanger isoforms. Am. J. Physiol. 37, C283-C296.
30. + exchanger gene family. J. Biol. Chem. 267, 9331-9339.
31. Pathak, R., Yokode, M., Hammer, R., Hofmann, S., Brown, M., Goldstein, J. and Anderson, R. (1990). Tissue-specific sorting of the human LDL receptor in polarized epithelia in transgenic mice. J. Cell Biol. 111, 347-359.
32. + antiport activity in hamster fibroblats precludes growth at neutral and acidic pH. Proc. Nat. Acad. Sci. USA 81, 4833-4837.
33. + antiporter. Cell 56, 271-280.
34. + antiporter, a glycoprotein of 110 kD. Science 247, 723-726.
35. Sargiacomo, M., Lisanti, M., Graeve, L., LeBivic, A. and Rodriguez-Boulan, E. (1989). Integral and peripheral protein compositions of the apical and basolateral membrane domains in MDCK cells. J. Membr. Biol. 107, 277-286.
36. Stevenson, B. R., Siliciano, J. D., Mooseker, M. S. and Goodenough, D. A. (1986). Identification of ZO-1, a high molecular weight polypeptide associated with the tight junction (Zonula Occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
37. Stevenson, B. R. and Begg, D. A. (1994). Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J. Cell Sci. 107, 367-375.
38. + exchanger isoform (NHE-3). J. biol. Chem. 267, 9340-9346.
39. + exchanger gene family. J. Membr. Biol. 134, 93-108.
40. + exchanger isoform (NHE2). J. Biol. Chem. 268, 11917-11924.
41. +-sensing'. Proc. Nat. Acad. Sci. USA 89, 2424-2428.
42. + exchanger isoform 1 (NHE1). J. Biol. Chem. 269, 5583-5588.
43. + exchanger from Caco-2 cells, a human intestinal cell line. Am. J. Physiol. 261, G229-G238.
44. +-ATPase: mislocation to apical plasma membranes in polycystic kidney disease epithelia. Am. J. Physiol. 260, F420-430.