A diaCEST MRI approach for monitoring liposomal accumulation in tumors

Journal of Controlled Release

Volumn 180, Issue 1, 2014, Pages 51-59

  Chan, Kannie W Y ^a,b   Yu, Tao ^a   Qiao, Yuan ^d   Liu, Qiang ^d   Yang, Ming ^a   Patel, Himatkumar ^a   Liu, Guanshu ^a,b   Kinzler, Kenneth W ^d   Vogelstein, Bert ^d   Bulte, Jeff W M ^a,b   Van Zijl, Peter C M ^a,b   Hanes, Justin ^a,c   Zhou, Shibin ^d   McMahon, Michael T ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Barbituric acid; CEST; Doxorubicin; Liposomes; MRI; Tumor necrosis factor

Indexed keywords

BIOCOMPATIBILITY; CELL DEATH; CHEMOTHERAPY; GLYCOPROTEINS; LIPOSOMES; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MAMMALS; MEDICAL NANOTECHNOLOGY;

BARBITURIC ACID; CEST; CHEMICAL EXCHANGE SATURATION TRANSFER; DOXORUBICIN; PERSONALIZED NANOMEDICINE; SYSTEMIC ADMINISTRATION; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTORS;

TUMORS;

BARBITURIC ACID; CD31 ANTIGEN; DOXORUBICIN; LIPOSOME; NANOCARRIER; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC ANTIBIOTIC; BARBITURIC ACID DERIVATIVE; CONTRAST MEDIUM; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER SIZE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CYTOTOXICITY; DIAMAGNETIC CHEMICAL EXCHANGE SATURATION TRANSFER NUCLEAR MAGNETIC RESONANCE IMAGING; DRUG ACCUMULATION; DRUG FORMULATION; DRUG RETENTION; DRUG UPTAKE; FEMALE; FLUORESCENCE IMAGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID BILAYER; LIPOSOMAL DELIVERY; MOUSE; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; TUMOR VASCULARIZATION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; HEK293 CELL LINE; HEPG2 CELL LINE; NEOPLASMS; PROCEDURES;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BARBITURATES; CONTRAST MEDIA; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HEK293 CELLS; HEP G2 CELLS; HUMANS; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MICE; NEOPLASMS; OPTICAL IMAGING; POLYETHYLENE GLYCOLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84895550020     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.02.005     Document Type: Article

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