Exchange rates of creatine kinase metabolites: Feasibility of imaging creatine by chemical exchange saturation transfer MRI

NMR in Biomedicine

Volumn 25, Issue 11, 2012, Pages 1305-1309

  Haris, Mohammad ^a   Nanga, Ravi Prakash Reddy ^a   Singh, Anup ^a   Cai, Kejia ^a   Kogan, Feliks ^a   Hariharan, Hari ^a   Reddy, Ravinder ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Acid dissociation constant; Adenosine 5 triphosphate; Chemical exchange saturation transfer; Chemical shift; Creatine; Exchange rate; Magnetic resonance imaging; Phosphocreatine

Indexed keywords

ACID DISSOCIATION CONSTANTS; ADENOSINE-5-TRIPHOSPHATE; CHEMICAL EXCHANGE SATURATION TRANSFER; CREATINE; EXCHANGE RATES; PHOSPHOCREATINE;

BIOMOLECULES; CHEMICAL SHIFT; DISSOCIATION; ENZYMES; FINANCE; MAGNETIC RESONANCE IMAGING; METABOLITES; ORGANIC COMPOUNDS; PHOSPHATES; PHYSIOLOGY; PROTONS;

CHROMIUM;

ADENOSINE TRIPHOSPHATE; CREATINE; CREATINE KINASE; CREATINE PHOSPHATE; PROTON;

ARTICLE; CHEMICAL EXCHANGE SATURATION TRANSFER; CHEMICAL PARAMETERS; DISSOCIATION CONSTANT; ION EXCHANGE; METABOLITE; NUCLEAR MAGNETIC RESONANCE SCANNER; PHANTOM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT;

AMINES; CREATINE; CREATINE KINASE; FEASIBILITY STUDIES; MAGNETIC RESONANCE IMAGING;

EID: 84868150699     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.2792     Document Type: Article

References (25)

1. Goldblatt H. The effect of high salt intake on the blood pressure of rabbits. Lab. Invest. 1969; 21(2): 126-128.
2. Gill SS, Thomas DG, Van Bruggen N, Gadian DG, Peden CJ, Bell JD, Cox IJ, Menon DK, Iles RA, Bryant DJ, Coutts GA. Proton MR spectroscopy of intracranial tumours: in vivo and in vitro studies. J. Comput. Assist. Tomogr. 1990; 14(4): 497-504.
3. Fenstermacher MJ, Narayana PA. Serial proton magnetic resonance spectroscopy of ischemic brain injury in humans. Invest. Radiol. 1990; 25(9): 1034-1039.
4. Narayana PA, Johnston D, Flamig DP. In vivo proton magnetic resonance spectroscopy studies of human brain. Magn. Reson. Imaging 1991; 9(3): 303-308.
5. Schmidt HC, Gooding CA, James TL, Gonzalez-Mendez R, James JL. Comparison of in vivo 31P-MR spectra of the brain, liver, and kidney of adult and infant animals. Pediatr. Radiol. 1986; 16(2): 144-149.
6. Stubbs M, Rodrigues LM, Gusterson BA, Griffiths JR. Monitoring tumor growth and regression by 31P magnetic resonance spectroscopy. Adv. Enzyme Regul. 1990; 30: 217-230.
7. Kemp GJ, Taylor DJ, Radda GK. Control of phosphocreatine resynthesis during recovery from exercise in human skeletal muscle. NMR Biomed. 1993; 6(1): 66-72.
8. Cadoux-Hudson TA, Blackledge MJ, Radda GK. Imaging of human brain creatine kinase activity in vivo. FASEB J. 1989; 3(14): 2660-2666.
9. Koretsky AP, Brosnan MJ, Chen LH, Chen JD, Van Dyke T. NMR detection of creatine kinase expressed in liver of transgenic mice: determination of free ADP levels. Proc. Natl. Acad. Sci. U. S. A. 1990; 87(8): 3112-3116.
10. Gruetter R, Weisdorf SA, Rajanayagan V, Terpstra M, Merkle H, Truwit CL, Garwood M, Nyberg SL, Ugurbil K. Resolution improvements in in vivo 1H NMR spectra with increased magnetic field strength. J. Magn. Reson. 1998; 135(1): 260-264.
11. Pfeuffer J, Tkac I, Provencher SW, Gruetter R. Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain. J. Magn. Reson. 1999; 141(1): 104-120.
12. Wolff SD, Balaban RS. NMR imaging of labile proton exchange. J. Magn. Reson. 1990; 86: 164-169.
13. Ward KM, Aletras AH, Balaban RS. A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST). J. Magn. Reson. 2000; 143(1): 79-87.
14. Sherry AD, Woods M. Chemical exchange saturation transfer contrast agents for magnetic resonance imaging. Annu. Rev. Biomed. Eng. 2008; 10: 391-411.
15. Zhou J, Payen JF, Wilson DA, Traystman RJ, van Zijl PC. Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat. Med. 2003; 9(8): 1085-1090.
16. van Zijl PC, Jones CK, Ren J, Malloy CR, Sherry AD. MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST). Proc. Natl. Acad. Sci. U. S. A. 2007; 04(11): 4359-4364.
17. Singh A, Haris M, Cai K, Kassey VB, Kogan F, Reddy D, Hariharan H, Reddy R. Chemical exchange saturation transfer magnetic resonance imaging of human knee cartilage at 3T and 7T. Magn. Reson. Med. 2011. DOI: 10.1002/mrm.23250.
18. Haris M, Cai K, Singh A, Hariharan H, Reddy R. In vivo mapping of brain myo-inositol. Neuroimage 2011; 54(3): 2079-2085.
19. Cai K, Haris M, Singh A, Kogan F, Greenberg JH, Hariharan H, Detre JA, Reddy R. Magnetic Resonance Imaging of Glutamate. Nat. Med. 2012; 18(2): 302-306.
20. Ward KM, Balaban RS. Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST). Magn. Reson. Med. 2000; 44(5): 799-802.
21. Woessner DE, Zhang S, Merritt ME, Sherry AD. Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI. Magn. Reson. Med. 2005; 53(4): 790-799.
22. McMahon MT, Gilad AA, Zhou J, Sun PZ, Bulte JW, van Zijl PC. Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly-L-lysine and a starburst dendrimer. Magn. Reson. Med. 2006; 55(4): 836-847.
23. Zhou J, Wilson DA, Sun PZ, Klaus JA, Van Zijl PC. Quantitative description of proton exchange processes between water and endogenous and exogenous agents for WEX, CEST, and APT experiments. Magn. Reson. Med. 2004; 51(5): 945-952.
24. Gutowsky HS, Saika A. Dissociation, chemical exchange, and the proton magnetic resonance in some aqueous electrolytes. J. Chem. Phys. 1953; 21: 1688-1694.
25. Liu G, Gilad AA, Bulte JW, van Zijl PC, McMahon MT. High-throughput screening of chemical exchange saturation transfer MR contrast agents. Contrast Media Mol. Imaging 2010; 5(3): 162-170.